Figure 1

Microscopic examination of the breast tumor. (A) Atypical lymphoid cells have infiltrated diffusely into the mammary glands (hematoxylin and eosin stain, original magnification × 4). (B) Cytokeratin stain enhances mammary ducts (arrowheads) (cytokeratin AE1/AE3 immunostain, original magnification × 4). (C) The neoplastic cells have a large nucleus containing prominent nucleoli and vesicular chromatin (hematoxylin and eosin stain, original magnification × 40). (D) The cells are positive for CD20 (CD20 immunostain, original magnification × 20).