The effects of sonic hedgehog signaling pathway components on non-small-cell lung cancer progression and clinical outcome

Table 6 Univariate and multivariate analyses of prognostic factors in non-small-cell lung cancer ^a

	P-value
Clinicopathological parameter	Univariate analysis^b	Multivariate analysis^c
Tumor size, <3 cm/>3 cm	0.885	0.108
Visceral pleural invasion, negative/positive	0.357	0.528
Lymph node metastasis, negative/positive	0.495	0.542
Lymphatic thromboembolism, negative/positive	0.976	0.997
Tumor recurrence, negative/positive	0.34	0.959
Distant metastasis, negative/positive	0.591	0.949
Shh expression, negative/positive	0.02^d	0.959
Gli1 expression, negative/positive	0.055	0.953
LYVE-1 expression, negative/positive	0.323	0.965
VEGFD expression, negative/positive	0.857	0.703

^aGli1, Glioma-associated oncogene homolog zinc finger protein 1; LYVE-1, Lymphatic vessel endothelial hyaluronan receptor 1; Shh, Sonic hedgehog; VEGF-D, Vascular endothelial growth factor D. ^bLogrank test; ^cCox regression model; ^dP < 0.05.

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