Figure 2

HCT-8 cell transplanted tumor (HE × 400). (A) Strong positive expression of PCNA protein on different phases after I-125 seed implantation; (B1) HCT-8 cell transplanted tumor before day 5 in the 0 mCi group (SP × 200); (B2) Day 5 in the 0.8 mCi group (SP × 400); (C1) Day 15 in the 0 mCi group (SP × 400); (C2) Day 15 in the 0.8 mCi group (SP × 400); (D1) 0 mCi group, a few apoptosis cells were seen, nuclei were stained blue and small nucleoli were seen; (D2) 0.8 mCi group, characteristic findings of cell apoptosis, germination was observed on day 10; (D3) 0.8 mCi group, vacuolization in the cytoplasm occurred in the apoptotic cell on day 15.