Table 1 Patient and tumor characteristics associated with the number of excised parathyroid glands
Number of parathyroid glands in resected specimen | P-value | |||||
|---|---|---|---|---|---|---|
Variable | 0 (A) N = 364 | 1 (B) N = 80 | 2 or more (C) N = 10 | Total n = 454 | A versus B | B versus C |
Age | 50.0 ± 12.5 | 52.2 ± 12.8 | 47.7 ± 6.08 | 50.3 ± 12.5 | 0.207 | 0.183 |
Gender | 0.551 | 0.603 | ||||
Male | 81 (22.3%) | 15 (18.7%) | 2 (20%) | 98 (21.6%) | ||
Female | 283 (77.7%) | 65 (81.3%) | 8 (80%) | 356 (78.4%) | ||
Tumor size | 11.5 ± 9.3 | 12.5 ± 7.6 | 13.6 ± 10.8 | 11.7 ± 9.1 | 0.034 | 0.820 |
Tumor multiplicity | 99/364 (27.2%) | 32/80 (40%) | 2/10 (20%) | 133/454 (29.3%) | 0.030 | 0.308 |
Tumor bilaterality | 80/364 (22.0%) | 23/80 (28.8%) | 0 | 103/454 (22.7%) | 0.192 | 0.059 |
Tumor location | 0.212 | 0.150 | ||||
Right | 145 (39.8%) | 23 (28.8%) | 3 (30%) | 171 (37.7%) | ||
Left | 128 (35.2%) | 32 (40%) | 7 (70%) | 167 (36.8%) | ||
Bilateral | 77 (21.2%) | 23 (28.8%) | 0 | 100 (22.0%) | ||
Confined to isthmus | 14 (3.8%) | 2 (2.5%) | 0 | 16 (3.5%) | ||
T classification | 0.045 | 0.109 | ||||
T1 | 203 (55.8%) | 34 (42.5%) | 4 (40.0%) | 241 (53.1%) | ||
T2 | 24 (6.6%) | 3 (3.8%) | 1 (10.0%) | 28 (6.2%) | ||
T3 | 134 (36.8%) | 43 (53.8%) | 4 (40.0%) | 181 (39.9%) | ||
T4 | 3 (0.6%) | 0 | 1 (10.0%) | 4 (0.9%) | ||
N classification | < 0.001 | 0.046 | ||||
N0 | 239 (65.7%) | 35 (43.8%) | 1 (10.0%) | 275 (60.6%) | ||
N1 | 125 (34.3%) | 45 (56.3%) | 9 (90.0%) | 179 (39.4%) | ||
TNM stage | 0.090 | 0.769 | ||||
I | 226 (62.1%) | 39 (48.8%) | 4 (40.0%) | 269 (59.3%) | ||
II | 9 (2.5%) | 1 (1.3%) | 0 | 10 (2.2%) | ||
III | 93 (25.5%) | 27 (33.8%) | 4 (40.0%) | 124 (27.3%) | ||
IV | 36 (9.9%) | 13 (16.3%) | 2 (20.0%) | 51 (11.2%) | ||
Extrathyroidal extension (minimal) | 157/364 (43.1%) | 47/80 (58.8%) | 5/10 (50%) | 209/454 (46.0%) | 0.013 | 0.737 |