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Table 3 Pooled risk estimates for the associations between carotenoids intake or blood carotenoids levels and bladder cancer risk

From: Vitamin A and risk of bladder cancer: a meta-analysis of epidemiological studies

Specific carotenoids

Number of studies

Pooled relative risk (95% CI)

Q-test for heterogeneity P value (I2score)

Carotenoids intake

Total carotenoids

4

0.67 (0.55, 0.79)

0.524 (0)

α-carotene

8

0.87 (0.76, 0.99)

0.221 (27.2%)

β-carotene

12

0.89 (0.82, 0.97)

0.084 (38.6%)

β-cryptoxanthin

6

0.86 (0.73, 1.00)

0.427(0)

Lutein/zeaxanthin

6

0.93 (0.70, 1.17)

0.035 (58.2%)

Lycopene

6

0.95 (0.82, 1.07)

0.54 (0)

Blood carotenoids level

Total carotenoids

2

0.43 (0.20, 0.93)

0.241 (27.3%)

α-carotene

4

0.56 (0.37, 0.75)

0.106 (51.0%)

β-carotene

4

0.41 (0.05, 0.78)

0.013 (72.4%)

β-cryptoxanthin

4

0.62 (0.06, 1.19)

0.027 (67.4%)

Lutein/zeaxanthin

4

0.50 (0.12, 0.87)

0.056 (50.2%)

Lycopene

4

0.60 (0.17, 1.03)

0.053 (61.0%)