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Table 1 Correlations of GRP78 and HPA expression in oral cancer with the clinicopathological parameters

From: Glucose-regulated protein 78 and heparanase expression in oral squamous cell carcinoma: correlations and prognostic significance

Variable n % GRP78 P HPA P
    Positive Negative   Positive Negative  
Tissue      0.003    0.033
Normal 10 17.9 0 10   0 10  
OSCC 46 82.1 27 19   19 27  
Gender      0.358    0.555
Male 37 80.4 20 17   14 23  
Female 9 19.6 7 2   5 4  
Age      0.606    0.055
≤60 27 58.7 15 12   8 19  
>60 19 41.3 12 7   11 8  
Tumor size      0.001    0.036
≤3.1 23 50.0 8 15   6 17  
>3.1 23 50.0 19 4   13 10  
Tumor stage      0.001    0.000
T1-T2 31 67.4 13 18   7 24  
T3-T4 15 32.6 14 1   12 3  
Lymphatic metastasis      0.000    0.012
N0 27 58.7 10 17   7 20  
N1-3 19 41.3 17 2   12 7  
Distant metastasis      0.033    0.000
M0 35 76.1 17 18   8 27  
M1 11 23.9 10 1   11 0  
TNM stage      0.000    0.000
I-II 23 50.0 6 17   3 20  
III-IV 23 50.0 21 2   16 7  
Histologic grade      0.018    0.016
G1-G2 12 26.1 11 1   9 3  
G3-G4 34 73.9 16 18   10 24  
Cigarette smoking      0.246    0.180
Yes 39 84.8 21 18   14 25  
No 7 15.2 6 1   5 2  
Alcohol drinking      0.787    1.000
Yes 36 78.3 22 14   15 21  
No 10 21.7 5 5   4 6  
  1. P <0.05 was considered to be statistically significant.