Figure 1

Immunohistochemistry staining patterns of GRP78 and HPA expressions in normal tissues and OSCC. (A) GRP78 expression in OSCC and normal tissues by immunostaining (×400). A-1: GRP78 in normal tissues: no expression; A-2: GRP78 in OSCC tissues: negative expression; A-3: GRP78 in OSCC tissues: positive expression. (B) HPA expression in OSCC and normal tissues by immunostaining (c × 400). B-1: HPA in normal tissues: no expression; B-2: HPA in OSCC tissues: negative expression; B-3: HPA in OSCC tissues: positive expression. GRP78, glucose-related protein 78; HPA, heparanase; OSCC, oral squamous cell carcinoma.