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Table 1 Characteristics of patients with or without loco-regional recurrence and distant metastasis after resection for clinical stage I NSCLC

From: Risk factors of postoperative recurrences in patients with clinical stage I NSCLC

 

Locoregional recurrence

Distant metastasis

 

No (n = 244) (100%)

Yes (n = 17) (100%)

p-valuea

No (n = 241) (100%)

Yes (n = 20) (100%)

p-valuea

Sex:

      

Male

110 (45.08)

7 (41.18)

0.806

108 (44.81)

9 (45)

0.989

Female

134 (54.92)

10 (58.82)

 

133 (55.19)

11 (55)

 

Histopathology:

      

Adenocarcinoma

209 (85.66)

17 (100)

0.140

210 (87.14)

16 (80)

0.322

Other

35 (14.34)

0 (0)

 

31 (12.86)

4 (20)

 

Differentiation:

      

Well

98 (40.16)

4 (23.53)

 

99 (41.08)

3 (15)

 

Moderate

97 (39.75)

5 (29.41)

0.032

93 (38.59)

9 (45)

0.035

Poor

49 (20.08)

8 (47.06)

 

49 (20.33)

8 (40)

 

Location:

      

Central

125 (51.23)

11 (64.71)

0.324

124 (51.45)

12 (60)

0.494

Peripheral

119 (48.77)

6 (35.29)

 

117 (48.55)

8 (40)

 

Adjuvant chemotherapy:

      

Yes

89 (36.48)

8 (47.06)

0.440

80 (33.2)

3 (15)

< 0.001

No

155 (63.52)

9 (52.94)

 

161 (66.8)

17 (85)

 

LVSI:

      

Absent

222 (90.98)

14 (82.35)

0.214

221 (91.7)

15 (75)

0.031

Present

22 (9.02)

3 (17.65)

 

20 (8.3)

5 (25)

 

Operation:

      

Lobectomy

228 (93.44)

17 (100)

0.609

225 (93.36)

20 (100)

0.620

Wedge

16 (6.56)

0 (0)

 

16 (6.64)

0 (0)

 

p-stage:

      

I

169 (69.26)

10 (58.82)

0.002

168 (69.71)

11 (55)

0.232

II

44 (18.03)

3 (17.65)

 

40 (16.60)

7 (35)

 

III

31 (12.71)

3 (17.65)

 

32 (13.28)

2 (10)

 

IV

0 (0)

1 (5.88)

 

1 (0.41)

0 (0)

 
  1. aSignificance was assessed using χ2 tests. Key: SCC, squamous cell carcinoma; LVSI, lymphovascular space invasion; p-stage, pathology stage.
  2. Statistically significant p values are depicted in underline.