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Table 1 Characteristics of patients with or without loco-regional recurrence and distant metastasis after resection for clinical stage I NSCLC

From: Risk factors of postoperative recurrences in patients with clinical stage I NSCLC

  Locoregional recurrence Distant metastasis
  No (n = 244) (100%) Yes (n = 17) (100%) p-valuea No (n = 241) (100%) Yes (n = 20) (100%) p-valuea
Sex:       
Male 110 (45.08) 7 (41.18) 0.806 108 (44.81) 9 (45) 0.989
Female 134 (54.92) 10 (58.82)   133 (55.19) 11 (55)  
Histopathology:       
Adenocarcinoma 209 (85.66) 17 (100) 0.140 210 (87.14) 16 (80) 0.322
Other 35 (14.34) 0 (0)   31 (12.86) 4 (20)  
Differentiation:       
Well 98 (40.16) 4 (23.53)   99 (41.08) 3 (15)  
Moderate 97 (39.75) 5 (29.41) 0.032 93 (38.59) 9 (45) 0.035
Poor 49 (20.08) 8 (47.06)   49 (20.33) 8 (40)  
Location:       
Central 125 (51.23) 11 (64.71) 0.324 124 (51.45) 12 (60) 0.494
Peripheral 119 (48.77) 6 (35.29)   117 (48.55) 8 (40)  
Adjuvant chemotherapy:       
Yes 89 (36.48) 8 (47.06) 0.440 80 (33.2) 3 (15) < 0.001
No 155 (63.52) 9 (52.94)   161 (66.8) 17 (85)  
LVSI:       
Absent 222 (90.98) 14 (82.35) 0.214 221 (91.7) 15 (75) 0.031
Present 22 (9.02) 3 (17.65)   20 (8.3) 5 (25)  
Operation:       
Lobectomy 228 (93.44) 17 (100) 0.609 225 (93.36) 20 (100) 0.620
Wedge 16 (6.56) 0 (0)   16 (6.64) 0 (0)  
p-stage:       
I 169 (69.26) 10 (58.82) 0.002 168 (69.71) 11 (55) 0.232
II 44 (18.03) 3 (17.65)   40 (16.60) 7 (35)  
III 31 (12.71) 3 (17.65)   32 (13.28) 2 (10)  
IV 0 (0) 1 (5.88)   1 (0.41) 0 (0)  
  1. aSignificance was assessed using χ2 tests. Key: SCC, squamous cell carcinoma; LVSI, lymphovascular space invasion; p-stage, pathology stage.
  2. Statistically significant p values are depicted in underline.