Surgical decompression improves recovery from neurological deficit and may provide a survival benefit in patients with diffuse large B-cell lymphoma-associated spinal cord compression: a case-series study

Table 2 Comparison of patients’ clinical characteristics in the surgical and nonsurgical groups

Characteristic	Surgical group (n = 6)	Nonsurgical group (n = 5)	P value
Age (years)	45.3 ± 7.7	59.2 ± 3.9	0.247^a
Gender			0.545^b
Male	1 (16.7%)	2 (40.0%)
Female	5 (83.3%)	3 (60.0%)
Time from symptoms and signs to treatment (days)	3.5 ± 1.1	10.8 ± 5.5	0.329^a
Performance status (ECOG)			0.455^b
< 2	2 (33.3%)	0 (0.0%)
≥ 2	4 (66.7%)	5 (100.0%)
Lactate dehydrogenase (IU/l)	300.8 ± 38.4	433.2 ± 149.6	0.792^a
Extra-nodal involvement >1 site			0.242^b
Yes	2 (33.3%)	4 (80.0%)
No	4 (66.7%)	1 (20.0%)
Stage			0.545^b
1	3 (50.0%)	1 (20.0%)
4	3 (50.0%)	4 (80.0%)
International Prognostic Index score			0.545^b
Low/low-intermediate	3 (50.0%)	1 (20.0%)
High/high-intermediate	3 (50.0%)	4 (80.0%)
Neurological deficit recovery			0.015^b
Complete	6 (100.0%)	1 (20.0%)
Partial	0 (0.0%)	4 (80.0%)
Overall survival (months)	48.6 ± 13.7	17.8 ± 3.4	0.177^a

Data presented as mean ± standard error of the mean or number (percentage). ECOG, Eastern Cooperative Oncology Group. ^aMann–Whitney U test. ^bFisher’s exact test.

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