Table 3 Relationship of KAP1 , TIMP1 and STC2 expression with pathological parameters of tumor
Clinical parameters | KAP1 | TIMP1 | STC2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Low | High | χ2 | P | Low | High | χ2 | P | Low | High | χ2 | P | |
N | 13 | 99 | 12 | 100 | 11 | 101 | ||||||
Gender | 1.52 | 0.22 | 0.68 | 0.41 | 3.08 | 0.079 | ||||||
Male | 7 | 70 | 7 | 70 | 5 | 72 | ||||||
Female | 6 | 29 | 5 | 30 | 6 | 29 | ||||||
Location | 0.184 | 0.91 | 1.82 | 0.40 | 1.99 | 0.369 | ||||||
Proximal | 1 | 11 | 0 | 12 | 0 | 12 | ||||||
Middle | 4 | 32 | 5 | 31 | 5 | 31 | ||||||
Distal | 8 | 56 | 7 | 57 | 6 | 58 | ||||||
Size | 0.227 | 0.633 | 0.156 | 0.693 | 0.484 | 0.487 | ||||||
<5 cm | 5 | 45 | 6 | 44 | 6 | 44 | ||||||
≥5 cm | 8 | 54 | 6 | 56 | 5 | 57 | ||||||
Lauren classification | 0.56 | 0.45 | 0.55 | 0.46 | 0.037 | 0.85 | ||||||
Intestinal | 8 | 50 | 5 | 53 | 6 | 52 | ||||||
Diffuse | 5 | 49 | 7 | 47 | 5 | 49 | ||||||
Histology | 1.53 | 0.675 | 5.376 | 0.146 | 2.62 | 0.454 | ||||||
Papillary adenocarcinoma | 0 | 5 | 0 | 5 | 0 | 5 | ||||||
Tubular adenocarcinoma | 11 | 69 | 12 | 68 | 10 | 70 | ||||||
Mucinous adenocarcinoma | 1 | 15 | 0 | 16 | 1 | 15 | ||||||
Signet-ring cell carcinoma | 1 | 10 | 0 | 11 | 0 | 11 | ||||||
Histologic differentiation | 0.013 | 0.91 | 1.97 | 0.16 | 0.10 | 0.75 | ||||||
Well-moderately | 4 | 32 | 6 | 30 | 4 | 32 | ||||||
Poorly-undifferentiated | 9 | 67 | 6 | 70 | 7 | 69 | ||||||
TNM Stages | 24.31 | 0.001 | 36.46 | 0.001 | 20.26 | 0.001 | ||||||
I | 7 | 7 | 8 | 6 | 6 | 8 | ||||||
II | 4 | 36 | 2 | 38 | 3 | 37 | ||||||
III | 2 | 37 | 2 | 37 | 1 | 38 | ||||||
IV | 0 | 19 | 0 | 19 | 1 | 18 | ||||||
Lymph node metastasis | 48.37 | 0.001 | 24.15 | 0.001 | 41.32 | 0.001 | ||||||
No | 7 | 1 | 5 | 3 | 6 | 2 | ||||||
Yes | 6 | 98 | 7 | 97 | 5 | 99 | ||||||
Distant metastasis | 0.898 | 0.343 | 2.746 | 0.098 | 0.537 | 0.464 | ||||||
No | 12 | 81 | 12 | 81 | 10 | 83 | ||||||
Yes | 1 | 18 | 0 | 19 | 1 | 18 | ||||||