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Table 4 Clinical response rate and pCR rate with different regimens

From: A retrospective study: platinum-based induction chemotherapy combined with gemcitabine or paclitaxel for stage IIB-IIIA central non-small-cell lung cancer

Variables

Radiographic response

CR/PR

SD/PD

RRa

P-value

pCR

All patients(n=82b)

45

37

55%

 

5(6%)

 gemcitabine

24

21

53%

 

2(4%)

 paclitaxel

18

11

62%

0.309

3(10%)

squamous (n=51)

29

22

57%

 

4(8%)

 gemcitabine

18

14

56%

  

 paclitaxel

11

8

58%

0.572

 

adenocarcinoma (n=29)

15

14

52%

 

1(3%)

 gemcitabine

6

6

50%

  

 paclitaxel

6

3

67%

  

 pemetrexed

3

5

38%

0.517

 
  1. aRR: response rate.
  2. bNote: Eight of the 82 patients who received pemetrexed were excluded in the comparison between gemcitabine and paclitaxel because pemetrexed was used only in patients with adenocarcinoma.