Table 2 Grading the severity of each parameter using Kleiner’s score[1]
Score | |||
|---|---|---|---|
Steatosis | Grade | <5% | 0 |
5–33% | 1 | ||
33–66% | 2 | ||
>66% | 3 | ||
Location | Zone 3 | 0 | |
Zone 1 | 1 | ||
Azonal | 2 | ||
Panacinar | 3 | ||
Microvesicular steatosis | Not present | 0 | |
Presented | 1 | ||
Fibrosis stage | None | 0 | |
Perisinusoidal or periportal | 1 | ||
Perisinusoidal and periportal/periportal | 2 | ||
Bridging fibrosis | 3 | ||
Cirrhosis | 4 | ||
Inflammation | Lobular inflammation | No foci | 0 |
<2 foci per 200× field | 1 | ||
2–4 foci per 200× field | 2 | ||
>4 foci per 200× field | 3 | ||
Liver cell injury | Ballooning | None | 0 |
Few balloon cells | 1 | ||
Many cells/ prominent ballooning | 2 | ||
Acidophil bodies | None to rare | 0 | |
Many | 1 | ||
Pigmented macrophages | None to rare | 0 | |
Many | 1 | ||
Other findings | Mallory's hyaline | None to rare | 0 |
Many | 1 | ||
Glycogenated nuclei | None to rare | 0 | |
Many | 1 |