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Table 5 Colorectal involvement in advanced ovarian cancer: literature review

From: Depth of colorectal-wall invasion and lymph-node involvement as major outcome factors influencing surgical strategy in patients with advanced and recurrent ovarian cancer with diffuse peritoneal metastases

Author/year

Patients (number)

Depth of bowel wall involvement (%)

Mesenteric nodal involvement (%)

Prognostic significance of pathological variables

Survival of optimally debulked patients

O’Hanlan[27](1995)

66

Serosa 41

72.7

Trend for patients with mesenteric nodal involvement to fail sooner

26 months

Muscolaris 42

Submucosa 14

Mucosa 3

Lax[28](1998)

31

Serosa 45

64.5

Trend for patients with mesenteric nodal involvement to fail sooner

21 months

Muscolaris 36

Mucosa 19

Scarabelli[29](2000)

66

Muscolaris 100

37.9

Prognostic significance of depth of bowel wall involvement at multivariate analysis for patients with mesenteric node metastases

5 years

42.2 %

Hertel[30](2001)

73

Serosa 38.5

Not reported

Not reported

Not reported

Muscolaris 42.4

Mucosa 19.1

Park[31](2006)

46

Serosa 71.7

15.2

Prognostic significance of depth of bowel wall involvement only for disease-free survival

32 months

Muscolaris + mucosa 28.3

Tebes[32](2006)

99

Serosa 33.3

Not reported

Not reported

Not reported

Muscolaris 39.4

Submucosa 13.1

Mucosa 14.2

Salani[33](2007)

31

Serosa 48

93.5

Not reported

Not reported

Muscolaris 29

Submucosa 7

Mucosa 16

Gallota[20](2011)

71

Serosa 45

51

NO

38 months overall

Muscolaris 25.4

Submucosa 12.7

30 months disease-free

Mucosa 16.9

Baiocchi[34](2011)

41

Serosa 34.1

70.7

Not reported

Not reported

Muscolaris 31.7

Submucosa 14.6

Mucosa 19.5

Gouy[35](2012)

47

Serosa 61.7

40.4

NO

4 years 60 %

Muscolaris 19.1

Submucosa 6.3

Mucosa 12.7

Present series

52

Serosa 25

42.3

Prognostic significance of depth of bowel wall involvement at multivariate analysis

35.5 months overall

Muscolaris 67.3

  

Mucosa 7.7

  

32.5 months disease-free