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Table 2 Main characteristics of the studies included in an analysis of the XRCC1 Arg399Gln polymorphism and bladder cancer risk

From: Quantitative assessment of the associations between XRCC1 polymorphisms and bladder cancer risk

Study Ethnicity Country Sample size (Frequency of A allele, %) HWE in control Quality score Genotyping method
Case no Control no
Stern [19] Caucasian US 235 (34.58) 213 (36.55) Yes 8 PCR-RFLP
Shen [33] Caucasian Italy 201 (32.09) 214 (34.11) Yes 9 PCR-RFLP
Sanyal [34] Caucasian Sweden 311 (35.21) 246 (31.71) Yes 9 PCR-RFLP
Broberg [35] Caucasian Sweden 61 (31.97) 155 (28.39) Yes 9 MALDI-TOF
Wu [20] Asian China 155 (27.74) 155 (46.45) Yes 8 PCR-RFLP
Matullo [21] Caucasian Mixed 131 (35.08) 1,094 (33.73) Yes 11 Taqman
Wu [22] Caucasian US 696 (34.01) 629 (33.72) Yes 10 Taqman
Karahalil [36] Caucasian Turkey 100 (32.00) 100 (38.00) Yes 7 PCR-RFLP
Sak [24] Caucasian UK 547 (35.71) 579 (36.52) Yes 11 Taqman
Figueroa [25] Caucasian Spain 1,150 (35.82) 1,149 (33.79) Yes 11 Taqman
Andrew [26] Caucasian US, Italy 1,029 (35.35) 1,281 (36.07) No 10 Taqman
Hsu [27] Asian Taiwan 221 (25.71) 223 (25.46) Yes 8 PCR-RFLP
Arizono [37] Asian Japan 251 (24.30) 251 (26.29) Yes 8 PCR-RFLP
Fontana [28] Caucasian France 51 (34.31) 45 (40.00) Yes 5 Taqman
Wang [30] Asian China 234 (32.26) 253 (29.45) Yes 7 PCR-RFLP
Bianchino [31] Caucasian Italy 32 (43.75) 242 (30.99) No 4 PCR-RFLP
Mittal [32] Asian India 212 (43.40) 250 (37.40) Yes 9 PCR-RFLP
Zhi [38] Asian China 302 (34.93) 311 (29.42) Yes 10 PCR-RFLP
  1. HWE, Hardy–Weinberg equilibrium.