Microsurgical management of giant malignant peripheral nerve sheath tumor of the scalp: two case reports and a literature review

Table 1 Literature review of studies of malignant peripheral nerve sheath tumor (MPNST) on the scalp

Study	Sex/age	Tumor location	Neurofibromatosis type 1	Bone infiltration	Immunohistochemistry S-100	Treatment	Follow-up
George [6]	F/56	Occipital	No	NA	+	Exc + RT	4 m, AWD
George [6]	M/50	Temporal	Yes	NA	+	Exc + RT	11 y, NED
Dabski [7]	NA/NA	Scalp	No	NA	NA	Exc	NA
Kikuchi [8]	M/59	Frontal	No	NA	+	Exc	5 y, NED
Demir [9]	M/80	Parietal	No	No	+	Exc + RT	6 m, NED
Garg [10]	M/50	Occipital	NA	Yes	+	Exc + RT	NA
Williams [11]	F/75	Scalp	No	NA	+	CT+Exc	2 y, NED
Fukushima [12]	M/38	Occipital	No	No	+	Exc	4 m, DOD
Kumar [13]	M/36	Occipital	No	Yes	+	Exc + RT	28 m, NED
Ge [14]	M/52	Parietal	Yes	Yes	+	Exc	6 m, NED
Hasturk [15]	M/44	Occipital	NA	No	+	Exc	NA
Shintaku [16]	F/59	Scalp	Yes	NA	_	Exc	18 m, DOD
Voth [17]	M/89	Parietal	No	No	+	Exc + RT	14 m, AWD
Jhawar [18]	F/43	Parietal	NA	Yes	NA	Exc	1 y, NED
Present cases	M/35	Occipital	No	Yes	_	Exc + RT	20 m, NED
	F/72	Occipital	No	Yes	+	Exc + RT	9 m (Re);
							15 m, AWD

AWD, alive with disease; CT, chemotherapy; DOD, dead of disease; Exc, excision; NA, not available; NED, no evidence of disease; Re, recurrence; RT, adjuvant radiotherapy.

ISSN: 1477-7819