Histopathological and clinical characteristics of duodenal gastrointestinal stromal tumors as predictors of malignancy

Table 1 Characteristics of patients with duodenal GISTs

Variable	Total	SkF group	non-SkF group	P value
Number	20	12	8
Age – yr (mean ± SD)	59.9 ± 11.6	63.6 ± 9.8	54.3 ± 12.3	0.048
Male/Female sex – no. (% male)	9/11 (45)	2/10 (16.7)	7/1 (87.5)	0.003
Presentation reason – no. (%)
Medical check-up	10 (50%)	6 (50%)	4 (50%)	0.675
Bleeding	3 (15%)	2 (17%)	1 (13%)	0.656
Anemia	5 (25%)	2 (17%)	3 (38%)	0.296
Others*	2 (10%)	2 (17%)	0 (0%)	0.347
Diagnostic method – no. (%)
Fiber-optic gastroscopy	14 (70%)	7 (58%)	7 (88%)	0.187
Abdominal ultrasonography	2 (10%)	1 (8%)	1 (13%)	0.653
Upper gastrography	2 (10%)	2 (17%)	0 (0%)	0.347
Abdominal computed tomography	1 (5%)	1 (8%)	0 (0%)	0.600
Operation for another gastrointestinal disease	1 (5%)	1 (8%)	0 (0%)	0.600
Therapeutic surgical procedure – no. (%)
Partial resection	17 (85%)	12 (100%)	5 (63%)	0.049
Distal gastrectomy	2 (10%)	0 (0%)	2 (25%)	0.147
Pancreaticoduodenectomy	1 (5%)	0 (0%)	1 (13%)	0.400
Site of tumor in duodenum – no. (%)
1st portion of the duodenum	5 (25%)	4 (33%)	1 (13%)	0.307
2nd portion of the duodenum	9 (45%)	5 (42%)	4 (50%)	0.535
3rd portion of the duodenum	4 (20%)	2 (17%)	2 (25%)	0.535
4th portion of the duodenum	2 (10%)	1 (8%)	1 (13%)	0.653
Risk of aggressive tumor behavior (modified AFIP consensus criteria)¹² – no. (%)
Very low risk	3	3	0	0.193
Low risk	9	9	0	0.001
High risk	8	0	8	<0.001

Data expressed as mean ± SD, where appropriate. AFIP = Armed Forces Institute of Pathology.
* One patient’s duodenal GIST was detected when she had a gastric smooth muscle tumor resected, and another patient’s duodenal GIST was detected as an incidental finding on a computed tomographic scan of the abdomen performed to screen for metastasis of malignant melanoma.

ISSN: 1477-7819