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Table 3 The relationship between CCT2 and PDIA3 expression and clinicopathological features of gallbladder AC

From: Clinicopathological features and CCT2 and PDIA2 expression in gallbladder squamous/adenosquamous carcinoma and gallbladder adenocarcinoma

Clinical and pathological features Case number CCT2 PDIA3
Positive number (%) χ2 P Positive number (%) χ2 P
Gender        
male 26 14(53.8) 0.000 0.990 14(53.8) 0.090 0.764
female 54 29(53.7) 31(57.4)
≤ 45        
> 45 16 5(31.3) 4.073 0.044 7(43.8) 1.270 0.260
Degree of differentiationa 64 38(59.4) 38(59.4)
well-differentiated        
moderately-Differentiated 27 10(37.0) 5.326 0.070 12 (44.4) 11.840 0.000
poorly-differentiated 25 14(56.0) 10(40.0)
Tumor maximum diameter (cm) 28 19(67.9) 23(82.1)
≤ 3 cm        
> 3 cm 50 22(44.0) 5.099 0.024 23(46.0) 5.692 0.017
Gallbladder stones 30 21(70.0) 22(73.3)
no        
yes 42 19(45.2) 2.577 0.108 25(59.5) 0.343 0.558
TNM stage 38 24(63.2)    20(52.6)   
I + II        
III 21 6(28.6)    7(33.3)   
IV 38 20(52.6) 11.625 0.003 20(52.6) 12.092 0.002
Lymph node metastasis 21 17(81.0)    18(85.7)   
no        
yes 30 10(33.3) 8.049 0.004 12(40.0) 5.150 0.020
Invasion 50 33(66.0) 33(66.0)
no        
yes 31 11(35.5) 6.793 0.009 14(45.2) 2.529 0.112
Surgical 49 32(65.3) 31(63.3)
radical        
palliative 26 8(30.8) 11.140 0.004 10(38.5) 7.940 0.019
biopsy 28 15(53.6) 15(53.6)
≤ 45 26 20(76.9)    20(76.9)   
  1. aComparison between well-differentiated and poorly-differentiated adenocarcinoma: χ2CCT2 = 5.24, P = 0.022; χ2PDIA3 = 8.44, P = 0.004; Comparison between moderately-differentiated and poorly-differentiated adenocarcinoma: χ2CCT2 = 0.79, P = 0.374; χ2PDIA3 = 9.98, P = 0.002.