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Table 2 Univariate survival analysis of overall survival and disease-free survival in 120 patients with ESCC

From: Overexpression of HSPA2 is correlated with poor prognosis in esophageal squamous cell carcinoma

Features Overall survival Disease-free survival
  Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
Age (≤60/>60 years) 0.713 (0.456 to 1.116) 0.139 0.745 (0.493 to 1.125) 0.162
Gender (female/male) 0.915 (0.553 to 1.513) 0.728 0.975 (0.624 to 1.525) 0.913
Drinking (yes/no) 1.043 (0.670 to 1.622) 0.853 1.017 (0.681 to 1.518) 0.935
Tumor site (upper + lower/middle) 1.347 (0.797 to 2.277) 0.266 1.216 (0.768 to 1.926) 0.405
Grade (G2 + G3 + G4/G1) 1.137 (0.739 to 1.749) 0.559 1.070 (0.723 to 1.584) 0.735
Primary tumor (T3 + T4/T1 + T2) 2.157 (1.380 to 3.372) 0.001a 1.872 (1.256 to 2.791) 0.002a
TNM stage (III/I + II) 21.177 (11.057 to 40.561) <0.001a 15.085 (8.320 to 27.350) <0.001a
Lymph node metastases (−/+) 0.572 (0.369 to 0.887) 0.012a 0.625 (0.418 to 0.935) 0.022a
HSPA2 expression (positive/negative) 3.557 (1.827 to 6.922) <0.001a 2.901 (1.721 to 4.888) <0.001a
  1. aP values considered statistically significant at <0.05. CI, confidence interval; ESCC, esophageal squamous cell carcinoma; G, grade; N, lymph node metastases; T, primary tumor. Drinking alcohol is defined as: average amount of drinking alcohol is 50 grams or more per day, and period of drinking continues to 1 year or more. Drinking alcohol parameter: amount of drinking/ day × years of drinking.