Figure 2

Immunohistochemical analysis of HSPA2 in ESCC samples, adjacent non-cancerous tissues and normal esophageal tissues (original magnification × 100). (A) Representative negative staining of HSPA2 in normal esophageal tissues. (B) Weak staining of HSPA2 in adjacent non-cancerous tissues. (C) Representative moderate staining and (D) strong staining of HSPA2 in ESCC tissues. The expression of HSPA2 was detected in cells of the basal layers of the esophagus (B), and HSPA2-positive staining was predominantly observed in the nucleus and some occurred in the cytoplasm in ESCC tissues (C,D). ESCC, esophageal squamous cell carcinoma.