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Table 3 Results of the univariate and multivariate analyses of overall survival in 46 patients with stage III-IV gastric cancer treated with neoadjuvant chemotherapy

From: Blood neutrophil-lymphocyte ratio predicts survival for stages III-IV gastric cancer treated with neoadjuvant chemotherapy

Factors Number Univariate analysisa, P value Multivariate analysisb
HR (95% CI) P value
Radicality     
 R0 37   0.127 (0.050 to 0.320) <0.001
 R1     
 R2 9 <0.001 1  
Differentiation     
 Differentiatedc 15    
 Poorly differentiatedd 31 0.061   
Pre-operative blood parameters     
 Neutrophils, cells/mm3     
  ≤4000 34    
  >4000 12 0.037   
 NLR     
  ≤2.5 26    
  >2.5 20 0.082   
  1. HR, hazard ratio; NLR, Neutrophil to lymphocyte ratio.
  2. aPerformed using the Kaplan-Meier analysis model and log-rank test; values of P <0.10 in the univariate analysis were entered into a multivariate analysis.
  3. bPerformed using Cox proportional hazards models with the backward likelihood method.
  4. cWell and moderately differentiated adenocarcinoma.
  5. dPoorly adenocarcinoma, ring cell carcinoma.