Blood neutrophil-lymphocyte ratio predicts survival for stages III-IV gastric cancer treated with neoadjuvant chemotherapy

Table 3 Results of the univariate and multivariate analyses of overall survival in 46 patients with stage III-IV gastric cancer treated with neoadjuvant chemotherapy

Factors	Number	Univariate analysis^a, P value	Multivariate analysis^b
Factors	Number	Univariate analysis^a, P value	HR (95% CI)	P value
Radicality
R0	37		0.127 (0.050 to 0.320)	<0.001
R1
R2	9	<0.001	1
Differentiation
Differentiated^c	15
Poorly differentiated^d	31	0.061
Pre-operative blood parameters
Neutrophils, cells/mm³
≤4000	34
>4000	12	0.037
NLR
≤2.5	26
>2.5	20	0.082

HR, hazard ratio; NLR, Neutrophil to lymphocyte ratio.
^aPerformed using the Kaplan-Meier analysis model and log-rank test; values of P <0.10 in the univariate analysis were entered into a multivariate analysis.
^bPerformed using Cox proportional hazards models with the backward likelihood method.
^cWell and moderately differentiated adenocarcinoma.
^dPoorly adenocarcinoma, ring cell carcinoma.

ISSN: 1477-7819