Pancreatic mucinous cystic neoplasm with sarcomatous stroma metastasizing to liver: a case report and review of literature

Table 1 Summary of reported cases of mucinous cystic neoplasm of pancreas with sarcomatous component

Reference	Demographic features		Epithelial component	Sarcomatous component
	Age	Sex	Histology	Histology	Immunohistochemistry findings
[8]	48	M	MCN, carcinosarcoma	Pleomorphism, high-grade atypia, atypical mitosis, necrosis	Vimentin (+)
				Pleomorphism, high-grade atypia, atypical mitosis, necrosis	ER, PR (−)
				Liver and lymph node metastasis of carcinoma	S100 (−)
					CD34 (−)
					SMA (−)
[9]	70	F	MCN, invasive adenocarcinoma	Spindle cell sarcoma	Vimentin (+)
[9]	70	F	MCN, invasive adenocarcinoma	Spindle cell sarcoma	Mucin 1 (+)
[10]	67	F	MCN, invasive adenocarcinoma	Pleomorphic sarcoma	Vimentin (+)
				Moderate to high-grade atypia	S100 (−)
				Atypical mitosis	c-Kit (−)
				Metastasis to liver
[3]	30	F	MCN	MCN with mesenchymal overgrowth	ER, PR (+)
				Mild atypia, low number of mitoses
				No metastasis
[11]	48	F	MCN with atypia	MCN with sarcomatous stroma	Vimentin, MSA, SMA
	48	F	MCN with atypia	MCN with sarcomatous stroma	ER and PR (+)
	66	F	MCN with atypia	MCN with sarcomatous stroma	Vimentin,
				Moderate to high-grade atypia	MSA, SMA,
				Numerous mitoses	S100 (variable),
				Distant metastasis	ER and PR (+)
	67	M	MCN, invasive adenocarcinoma	MCN with sarcomatous stroma	Vimentin,
				MCN with sarcomatous stroma	MSA, SMA,
				Moderate to high-grade atypia	S100 (+)
				Moderate to high-grade atypia	ER and PR (−)
				Numerous mitoses
				Omental metastasis
[5]	43	F	MCN	MFH	Vimentin, lysozyme, α1 antitrypsin
[4]	45	F	MCN	Pseudosarcomatous, mural nodules	CK, EMA, Vimentin

ER, estrogen receptor; MCN, mucinous cystic neoplasm; MFH, malignant fibrous histiocytoma; MSA, muscle-specific actin; PR, progesterone receptor; SMA, smooth muscle actin.

ISSN: 1477-7819