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Table 3 Subgroup analysis of fluid accumulation on the basis of ultrasonography performed at 24 hours in the drain and no-drain groups with respect to type of surgery, size of gland and histological diagnosis

From: The impact of routine open nonsuction drainage on fluid accumulation after thyroid surgery: a prospective randomised clinical trial

  Mean fluid accumulation at 24 hours (ml)
Measurement parameter Drain group P -value No-drain group P -value
Type of surgery     
Lobectomy and isthmusectomy 16.3 0.969 22.4 0.309
Total 18.7 0.450 42.7 0.021
Completion 12.2 0.271 8.9 0.026
Histological size     
Below overall median size (36.5 cm3) 16.2   19.5  
Above overall median size (36.5 cm3) 20.0 0.166 36.7 0.012
Histological diagnosis     
Cancer 17.9 0.560 20.2 0.483
Hypervascular disorders 14.7 0.450 15.1 0.310
Other (benign) diagnoses 15.9 0.751 18.0 0.900
  1. P-values (two-paired Student’s t-test) were derived by comparing the ultrasound-based volume at the corresponding end point to the ultrasound-based volume of the remaining patients within the same group (that is, drain group versus no-drain group)