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Table 3 Univariate and multivariate overall survival analysis for 227 patients with gastric cancer

From: Prognosis significance of HER-2/neu overexpression/amplification in Chinese patients with curatively resected gastric cancer after the ToGA clinical trial

Variables

Univariate

Multivariate

5-year survival rate

P

Hazard ratio

P

Age

 

0.773

  

  ≥65 years

39.3

   

  <65 years

41.9

   

Sex

 

0.230

  

  male

43.3

   

  female

34.3

   

Lauren

 

<0.001

 

0.006

  intestinal

48.6

 

1

 

  diffuse

18.4

 

1.467

 

  mixed

38.2

 

1.201

 

WHO classification

 

0.001

 

0.003

  W/D

63.6

   

  M/D

45.1

   

  P/D

24.7

   

Tumor size

 

0.001

  

  ≥5 cm

21.1

 

1.395

0.005

  <5 cm

53.9

 

1

 

Tumor location

 

0.368

 

0.647

  cardia

40.3

   

  corpus

35.9

   

  antrum

50.0

   

Invasion depth

 

<0.001

 

0.604

  T1

85.0

   

  T2

66.7

   

  T3

29.8

   

Lymph node

 

<0.001

 

<0.001

  present

25.4

   

  absent

64.0

   

TNM stage

 

0.007

 

<0.001

  I

76.1

 

1

 

  II

51.7

 

1.364

 

  III

22.0

 

1.571

 

Vessel invasion

 

0.001

 

0.016

  present

15.0

 

1.916

 

  absent

43.0

 

1

 

Borrmann

 

0.471

 

0.221

  I

73.3

   

  II

39.5

   

  III

32.9

   

  IV

0

   

HER-2 overexpression

   

0.351

  positive

27.3

0.031

  

  negative

42.8

   
  1. M/D: moderately differentiated; P/D: poorly differentiated; W/D: well differentiated.
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World Journal of Surgical Oncology

ISSN: 1477-7819

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