Table 2 Univariate and multivariate Cox proportional hazard regression analyses of the relationship between miRNA let-7i levels, clinicopathological characteristics, and prognosis in LAGC patients

Univariate analysis ( n = 86)

Age

≥59 versus <59

0.665

0.205

Sex

Male versus female

0.715

0.313

Let-7i level

Fold change

2.436

0.016

TNM stage

II versus III

3.478

0.003

Depth of infiltration

T₂ versus T_3-4

5.691

<0.001

Differentiation degree

Well-moderate versus poor

2.128

0.029

Site

Distal, middle, or upper third

0.779

0.347

Lymph node metastasis

N₁ versus N₂

2.936

0.008

Multivariate analysis ( n = 86)

Age

≥59 versus <59

0.622

0.356

Sex

Male versus female

0.576

0.463

Let-7i level

Fold change

2.316

0.024

TNM stage

II versus III

3.226

0.013

Depth of infiltration

T₂ versus T_3-4

4.167

<0.001

Differentiation degree

Well to moderate versus poor

0.798

0.166

Site

Distal, middle, or upper third

0.535

0.572

Lymph node metastasis

N₁ versus N₂

2.245

0.037