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Table 1 Reported cases of implantation metastasis from colorectal adenocarcinoma into a fistula in ano

From: Rectosigmoid adenocarcinoma revealed by metastatic anal fistula. The visible part of the iceberg: a report of two cases with literature review

Author

Year

Age

Gender

Location of the primary tumor

Duration of anal fistula

Stage

Histology ADK Different

Operation

Follow up without recurrrence

Guiss A[4]

1954

47

M

S

2 m

Dukes A

Mod

APR

1 y 2 m

Killingback et al.[5]

1965

63

M

S

8 y

Dukes A

Well

APR

NA

Parnes[6]

1976

47

M

S

3 m

Dukes B

Well

APR

18 m

Rollinson and Dundas[7]

1984

65

M

Rs

20 y

NA

Well

APR

10 m

Ueta et al.[8]

1991

66

F

S

44

Dukes B

Well

APR

6 m

Thomas and Thompson[9]

1992

68

M

S

1 y

Dukes B

Mod

APR

NA

Tohira et al. (Japenese)[10]

1998

75

M

UR

40 y

Dukes B

Well

APR

1 y

Isbister[18]

2000

47

M

Rs

2 y M

Dukes C

Mod

1- LR

NA

2- LOR

Isbister[18]

2000

39

M

S

N 1 y M

NA

NA

Refused APR

NA

Tokuhara et al.[11]

2001

69

M

S

5 y

Dukes B

Mod

APR

1 y

Yoshimura et al.[12]

2001

59

M

Rs

29 y

Dukes C

Mod

APR

3 y 7 m

Shinohara et al.[19]

2001

36

M

MR

16 y

Dukes C

Mod

AR + LR

6 m

Kouraklis et al.[13]

2002

75

M

S

1 y

Dukes B

Mod

APR

NA

Yagihashi et al.[14]

2002

50

M

S

NA

Dukes C

Well

TPE

3 y 8 m

Shimoyama et al.[15]

2003

61

M

Rs

5 y

Dukes C

Mod

APR

5 y

Hyman and Kida[16]

2003

66

M

S

15 y

Dukes B

Mod CK7-/CK20+

APR

1 y

Zbar and Shenoy[20]

2004

72

M

S

4 y

NA

NA

S + LR + adj CH RTH

1 y 2 m

Gupta et al.[21]

2005

44

M

Left colon

1 m

Dukes C

Mod

LH = LR

3 y

Hamada et al.[23]

2005

53

M

S

7 y

Dukes B

Well CK7-/CK20+

AR + LR

1 y

Ishiyama et al.[24]

2006

53

M

UR

20 y

Dukes C

Mod

AR + LR

10 m died from carcinomatosis

Sandiford et al.[25]

2006

72

M

Rs

2 y

Dukes B

Mod

S + LR + adj Ch R

14 m

Gravante et al.[17]

2008

64

M

Left colon

NA

Dukes A

Mod CK7-/CK20+

1-LH

1 y

2-APR + adj CH RTH

Wakatsuki et al.[26]

2008

57

M

Rs

7 y

Dukes B

Mod CK7-/CK20+

1-AR

3y7m

After 2 years 2- LR

Our report

2012

68

M

Rs

2 m

Dukes B

Well CK7-/CK20+

Neoadju chemoradia AR + LR

3 y

Our report

2012

55

M

Rs

10 y

Dukes B

Well CK7-/CK20+

Neoadju chemoradia AR + LR

3 y

  1. S, sigmoid; Rs, rectosigmoid; R, rectum; Mod, moderately differentiated; Well, well-differentiated; APR, abdominoperineal resection; TPE, total pelvic exenteration; LAR, low anterior resection; LOR, local resection; adj, adjuvant; Neoadju chemoradia, neoadjuvant chemoradiation therpay; y, year(s); m, months; M, male; F, female; A, alive; L, left colon; LH, left hemicolectomy; UR, Upper rectum; MR, middle rectum; ADK, adenocarcinoma.CH: chemotherapy; RTH; radiotherapy; NA: not available.