From: Expression and significance of the TLR4/MyD88 signaling pathway in ovarian epithelial cancers
TLR4 | MyD88 | NF-κB | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Positive | Negative | P | Positive | Negative | P | Positive | Negative | P | ||
Histologic type | Serous | 23 | 37 | 0.001 | 20 | 40 | 0.003 | 40 | 20 | 0.037 |
Mucinous | 6 | 19 | 5 | 20 | 15 | 10 | ||||
Endometrioid | 7 | 4 | 2 | 9 | 4 | 7 | ||||
Clear cell | 19 | 6 | 16 | 9 | 20 | 5 | ||||
Undifferentiated | 2 | 0 | 2 | 0 | 1 | 1 | ||||
Histologic grade | Grade 1 | 15 | 20 | 0.469 | 8 | 27 | 0.083 | 25 | 10 | 0.640 |
Grade 2 | 32 | 30 | 24 | 38 | 39 | 23 | ||||
Grade 3 | 10 | 16 | 13 | 13 | 16 | 10 | ||||
Tumor size | <10 cm | 26 | 35 | 0.471 | 24 | 37 | 0.577 | 39 | 22 | 0.851 |
≥10 cm | 31 | 31 | 21 | 41 | 41 | 21 | ||||
Mitotic count | <10/10HPFs | 25 | 25 | 0.569 | 16 | 34 | 0.660 | 35 | 15 | 0.541 |
10 ≤ but <20/10HPFs | 21 | 23 | 18 | 26 | 26 | 18 | ||||
≥20/10HPFs | 11 | 18 | 11 | 18 | 19 | 10 | ||||
FIGO stage | I/II | 26 | 36 | 0.368 | 16 | 46 | 0.015 | 38 | 24 | 0.451 |
III/IV | 31 | 30 | 29 | 32 | 42 | 19 | ||||
Disease recurrence | No | 27 | 35 | 0.589 | 16 | 46 | 0.015 | 40 | 22 | 0.526 |
Yes | 30 | 31 | 29 | 32 | 40 | 21 |