Meta-analysis of surgical resection and radiofrequency ablation for early hepatocellular carcinoma

Table 2 Main results of the pooled data in the meta-analysis

Variables	Number of references with data	OR (95% CI)	Q test (P value)	I²(%)	Z test (P value)	Begg’s test (P value)	Egger’s test (P value)
Overall survival rates
1 year	12 [16, 19–21, 24–27, 29–32]	0.60(0.42, 0.86)	0.301	14.6	0.005	0.54	0.40
3 years	13 [16, 19–21, 24–32]	0.49(0.36, 0.65)	0.036	45.8	0.000	0.2	0.15
5 years	10 [16, 24–32]	0.60(0.43, 0.84)	0.003	63.7	0.003	0.37	0.57
Recurrence rates
1 year	13 [16, 19–21, 24–32]	1.48(1.05, 2.08)	0.001	63.4	0.025	1.00	0.61
3 years	13 [16, 19–21, 24–32]	1.76(1.49, 2.08)	0.000	69.9	0.000	0.20	0.15
5 years	10 [16, 24–32]	1.68(1.21, 2.34)	0.02	54.4	0.002	0.86	0.92
Local recurrence	4 [16, 20, 24, 30]	0.34(0.09, 1.28)	0.02	68.9	0.112	NA	NA
Complications	7 [16, 19, 24, 25, 27, 30, 32]	6.25(3.12, 12.52)	0.042	54	0.000	1	0.982

NA,not available.Q test and I² were used to evaluate the heterogeneity of the studies; Z test was used to value the combined effect; Begg’s and Egger’s tests were used to assess the publication bias.

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