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Table 1 Treatments for recurrent tumors of the present case before the AFTV injection

From: Autologous formalin-fixed tumor vaccine suppressed re-recurrence of HCV-related hepatocellular carcinoma following 29 unsuccessful treatments with extensive conventional therapy: a case report

Treatment number

Year. Month

Treatments

1

2001.09

TAE to the 5 cm primary tumor in S8

2

2002.02-03

TAE to recurrent tumor

3, 4, 5

2002.11-12

Acetic acid injection, three times; no effect

6, 7

2003.09

TAE + RFA; tumor shrinkage

8

2004.08

TAE, no effect

9

2004.11

First surgical resection; incomplete resection

10

2004.12

TAI with epirubicin

11

2005.02

TAE for portal vein tumor thrombosis (Vp4)

12, 13, 14, 15

2005.03-07

Chemotherapy with 5FU and IFNa, preliminary course + three courses; no change

16

2005.09

Second surgical resection of portal vein tumor (Vp4)

17, 18, 19

2006.01-05

Chemotherapy with 5FU and IFNa, three courses

20

2006.06

TAE in S7

21

2006.10-11

Chemotherapy with 5FU and IFNa, an additional course

22, 23, 24

2007.02

MTC, PEIT, lipiodol embolization to the recurrent HCC in S7

25, 26

2007.03

RFA + PEIT; no effect

27

2007.05

Chemotherapy with 5FU and IFNa, an additional course

28

2007.08

TAE for 1.2 cm tumor in S7; no effect

29

2007.11

Third surgical resection after thoracotomy and partial thoracic diaphragm removal

  1. 5FU, 5-fluorouracil; IFNa, interferon-alpha; HCC, hepatocellular carcinoma; MTC, microwave tumor coagulation; PEIT, percutaneous ethanol injection therapy; RFA, radiofrequency ablation; TAE, transarterial embolization; TAI, transcatheter hepatic artery infusion chemotherapy.
  2. The above treatments were carried out at three different institutions prior to presentation at our clinic and were recorded by the patient himself without precise descriptions. After the 29th treatment, a single course of AFTV injection [5] was initiated in July 2008 with no further treatment.