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Table 1 Clinical characteristics of 22 patients with metastatic melanoma who underwent laparoscopic liver resection for tumor-infiltrating lymphocyte harvest

From: Minimally invasive liver resection to obtain tumor-infiltrating lymphocytes for adoptive cell therapy in patients with metastatic melanoma

Variable

n

%

Number of patients

22

 

Age at time of resection (years)

48 (33–64)

 

Sex

  

 Male

14

64

 Female

8

36

Prior systemic treatment

  

 None

4

18

 IL-2

11

50

 IFN alpha 2b

10

45

 Adoptive cell transfer

1

4.5

 Chemotherapy

3

14

 Biochemotherapy*

1

4.5

 Vaccine

3

14

 Anti-CTLA-4 antibody

2

9

 Tyrosine kinase inhibitor

1

4.5

 BRAF inhibitor

1

4.5

Indication for metastasectomy

  

 TIL

20

91

 TIL/NED

2

9

 Diagnosis

0

0

  1. *Biochemotherapy = chemotherapy combined with IL-2 or IFN alpha 2b. TIL, tumor-infiltrating lymphocyte; NED, no evidence of disease.