Table 2 Relationship of S100A6 expression with pathological parameters of tumor

Age(years)

57.17 ± 12.38

60.38 ± 11.78

−2.741

0.006

Gender

0.119

0.730

Male

130(41.8%)

181(58.2%)

Female

50(40.0%)

75(60.0%)

Location

6.130

0.047

Proximal

16(29.1%)

39(70.9%)

Middle

63(38.7%)

100(61.3%)

Distal

101(46.3%)

117(53.7%)

Size

21.212

0.000

<5cm

129(50.4%)

127(49.6%)

≥5cm

51(28.3%)

129(71.7%)

Lauren classification

0.157

0.692

Intestinal

107(40.5%)

157(59.5%)

Diffuse

73(42.4%)

99(57.6%)

Histology classification

7.658

0.054

Papillary adenocarcinoma

9(56.3%)

7(43.7%)

Tubular adenocarcinoma

134(41.1%)

192(58.9%)

Mucinous adenocarcinoma

6(20.7%)

23(79.3%)

Signet-ring cell carcinoma

31(47.7%)

34(52.3%)

Histologic differentiation

1.076

0.783

Well

7(53.8%)

6(46.2%)

Moderately

54(42.2%)

74(57.8%)

Poorly

118(40.3%)

175(59.7%)

Others

1(50.0%)

1(50.0%)

Invasion depth

78.106

0.000

T1

51(89.5%)

6(10.5%)

T2

62(56.9%)

47(43.1%)

T3

65(26.6%)

179(73.4%)

T4

2(7.7%)

24(92.3%)

TNM Stages

185.557

0.000

I

78(86.7%)

12(13.3%)

II

70(67.3%)

34(32.7%)

III

27(15.6%)

146(84.4%)

IV

5(7.2%)

64(92.8%)

Lymphatic metastasis

110.475

0.000

No

121(72.9%)

45(27.1%)

Yes

59(21.9%)

211(78.1%)

Regional lymph nodes

121.478

0.000

PN0

121(72.9%)

45(27.1%)

PN1

43(31.6%)

93(68.4%)

PN2

13(13.1%)

86(86.9%)

PN3

3(8.6%)

32(91.4%)

Distant metastasis

28.936

0.000

No

174(46.4%)

201(53.6%)

Yes

6(9.8%)

55(90.2%)