Table 1 Relationship of Annexin II expression with pathological parameters of tumor

Age(years)

56.69 ± 11.94

62.57 ± 11.57

−5.098

0.000

Gender

0.812

0.367

Male

182(69.7%)

129(73.7%)

Female

79(30.3%)

46(26.3%)

Location

8.559

0.014

Proximal

23(8.8%)

32(18.3%)

Middle

101(38.7%)

62(35.4%)

Distal

137(52.5%)

81(46.3%)

Size

32.555

0.000

<5cm

182(69.7%)

74(42.3%)

≥5cm

79(30.3%)

101(57.7%)

Lauren classification

10.277

0.001

Intestinal

142(54.4%)

122(69.7%)

Diffuse

119(45.6%)

53(30.3%)

Histology classification

7.658

0.054

Papillary adenocarcinoma

9(3.4%)

7(4.0%)

Tubular adenocarcinoma

189(72.4%)

137(78.3%)

Mucinous adenocarcinoma

13(5.0%)

16(9.1%)

Signet-ring cell carcinoma

50(19.2%)

15(8.6%)

Histologic differentiation

1.076

0.783

Well

12(4.6%)

1(0.6%)

Moderately

69(26.4%)

59(33.7%)

Poorly

179(68.6%)

114(65.1%)

Others

1(0.4%)

1(0.6%)

Invasion depth

61.527

0.000

T1

56(21.5%)

1(0.6%)

T2

75(28.7%)

34(19.4%)

T3

124(47.5%)

120(68.6%)

T4

6(2.3%)

20(11.4%)

TNM Stages

189.886

0.000

I

78(43.3%)

12(4.7%)

II

71(39.4%)

33(12.9%)

III

26(14.4%)

147(57.4%)

IV

5(2.8%)

64(25.0%)

Lymphatic metastasis

91.842

0.000

No

147(56.3%)

19(10.9%)

Yes

114(43.7%)

156(89.1%)

Regional lymph nodes

111.626

0.000

PN0

147(56.3%)

19(10.9%)

PN1

71(27.2%)

65(37.1%)

PN2

39(14.9%)

60(34.3%)

PN3

4(1.5%)

31(17.7%)

Distant metastasis^a

30.214

0.000

No

244(93.5%)

131(74.9%)

Yes

17(6.5%)

44(25.1%)

S100A6

120.198

0.000

High

163(90.6%)

17(9.4%)

Low

98(38.3%)

158(61.7%)