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  1. The prognosis of colon cancer (CC) is challenging to predict due to its highly heterogeneous nature. Ferroptosis, an iron-dependent form of cell death, has roles in various cancers; however, the correlation be...

    Authors: Ye Wang, Heng-bo Xia, Zhang-ming Chen, Lei Meng and A-man Xu

    Citation: World Journal of Surgical Oncology 2021 19:135

    Content type: Research

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  2. Medulloblastoma (MB) is the most common pediatric embryonal tumor. Accurate identification of cerebral spinal fluid (CSF) dissemination is important in prognosis prediction. Both MRI of the central nervous sys...

    Authors: Hui Zheng, Jinning Li, Huanhuan Liu, Chenqing Wu, Ting Gui, Ming Liu, Yuzhen Zhang, Shaofeng Duan, Yuhua Li and Dengbin Wang

    Citation: World Journal of Surgical Oncology 2021 19:134

    Content type: Research

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  3. BLCA is a common cancer worldwide, and it is both aggressive and fatal. Immunotherapy (ICT) has achieved an excellent curative effect in BLCA; however, only some BLCA patients can benefit from ICT. MT1L is a p...

    Authors: Yanpeng Ding, Nuomin Liu, Mengge Chen, Yulian Xu, Sha Fang, Wenbin Xiang, Xinying Hua, Gaili Chen, Yahua Zhong and Haijun Yu

    Citation: World Journal of Surgical Oncology 2021 19:133

    Content type: Research

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  4. To compare the postoperative recurrence and fertility in patients with borderline ovarian tumors (BOTs) who underwent different surgical procedures: salpingo-oophorectomy versus cystectomy.

    Authors: Peng Wang and Lei Fang

    Citation: World Journal of Surgical Oncology 2021 19:132

    Content type: Research

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  5. Radiotherapy is a main therapeutic method for cancers, including colon cancer. In the current study, we aim to explore the effects of circular RNA (circRNA) circ_0055625 in the progression and radiosensitivity...

    Authors: Chao Gao, Yi Zhang, Yanming Tian, Chun Han, Lan Wang, Boyue Ding, Hua Tian, Chaoxi Zhou, Yingchao Ju, Ale Peng and Qiyao Yu

    Citation: World Journal of Surgical Oncology 2021 19:131

    Content type: Research

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  6. The application of side-to-end anastomosis (SEA) in sphincter-preserving resection (SPR) is controversial. We performed a meta-analysis to compare the safety and efficacy of SEA with colonic J-pouch (CJP) anas...

    Authors: Sen Hou, Quan Wang, Shidong Zhao, Fan Liu, Peng Guo and Yingjiang Ye

    Citation: World Journal of Surgical Oncology 2021 19:130

    Content type: Review

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  7. During the past two decades, laparoscopic radical nephroureterectomy (LRNU) has been proposed as an alternative technique to open radical nephroureterectomy (ORNU) and has become increasingly accepted for the ...

    Authors: Radosław Piszczek, Łukasz Nowak, Wojciech Krajewski, Joanna Chorbińska, Sławomir Poletajew, Marco Moschini, Krzysztof Kaliszewski and Romuald Zdrojowy

    Citation: World Journal of Surgical Oncology 2021 19:129

    Content type: Review

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  8. Although the ACOSOG Z0011 study showed that axillary lymph node dissection (ALND) could be avoided in a specific population of sentinel lymph node-positive patients, it is not widely accepted by Chinese surgeo...

    Authors: Yuan Peng, Miao Liu, Xianan Li, Fuzhong Tong, Yingming Cao, Peng Liu, Bo Zhou, Hongjun Liu, Lin Cheng, Jiajia Guo, Fei Xie, Houpu Yang, Siyuan Wang, Chaobin Wang, Yalin Chen and Shu Wang

    Citation: World Journal of Surgical Oncology 2021 19:128

    Content type: Research

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  9. Most previous studies compared survival between left-sided and right-sided colon cancer without adjustment for clinicopathological parameters. We investigated the effect of sidedness on survival among patients...

    Authors: Zhuang-Sheng Huang, Jun-Wei Wu, Ying Li, Yu-Hai Lin and Xu-Yuan Li

    Citation: World Journal of Surgical Oncology 2021 19:127

    Content type: Research

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  10. Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with poor prognosis. Radical surgery is the best option for cure and, nowadays, it is performed by many surgeons also in cases of vascular in...

    Authors: Claudio F. Feo, Giulia Deiana, Chiara Ninniri, Giuseppe Cherchi, Paola Crivelli, Alessandro Fancellu, Giorgio C. Ginesu and Alberto Porcu

    Citation: World Journal of Surgical Oncology 2021 19:126

    Content type: Research

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  11. Lymphovascular invasion (LVI) is defined as the presence of cancer cells in lymphatics or blood vessels. This study aimed to evaluate the prognostic value of LVI in stage II colorectal cancer (CRC) patients wi...

    Authors: Zhenyan Gao, Huihua Cao, Xiang Xu, Qing Wang, Yugang Wu and Qicheng Lu

    Citation: World Journal of Surgical Oncology 2021 19:125

    Content type: Research

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  12. Adjuvant tegafur-gimeracil-oteracil (S-1) is commonly used for gastric cancer in Asia, and tegafur-uracil (UFT) is another oral fluoropyrimidine when S-1 is unavailable. The real-world data of adjuvant UFT has...

    Authors: Hung-Hsuan Yen, Chiung-Nien Chen, Chi-Chuan Yeh and I-Rue Lai

    Citation: World Journal of Surgical Oncology 2021 19:124

    Content type: Research

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  13. Pancreatic cancer (PAC) is one of the most devastating cancer types with an extremely poor prognosis, characterized by a hypoxic microenvironment and resistance to most therapeutic drugs. Hypoxia has been foun...

    Authors: Jianfeng Ding, Xiaobo He, Xiao Cheng, Guodong Cao, Bo Chen, Sihan Chen and Maoming Xiong

    Citation: World Journal of Surgical Oncology 2021 19:123

    Content type: Research

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  14. Long non-coding RNA (lncRNA) prostate androgen-regulated transcript 1 (PART1) was previously shown to exert an oncogenic role in several human cancers. However, whether PART1 is associated with the malignant p...

    Authors: Xibao Hu, Lei Zhang, Jingjing Tian and Junhong Ma

    Citation: World Journal of Surgical Oncology 2021 19:122

    Content type: Research

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  15. It has been reported that long-chain non-coding RNA (lncRNA) zinc finger E-box binding homeobox 1 antisense 1 (ZEB1-AS1) is an oncogene in various cancers, including hepatocellular carcinoma (HCC). We investig...

    Authors: Shuai Xue, Fengqin Lu, Chunhui Sun, Jingjing Zhao, Honghua Zhen and Xin Li

    Citation: World Journal of Surgical Oncology 2021 19:121

    Content type: Research

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  16. The Chinese Society of Clinical Oncology guidelines 2018 and the recent update of that (version 2020) recommends accurate examination before major treatment for decision(s) in cases of colon cancer. Also, the ...

    Authors: Yadong Zhou, Zhiwei Han, Fafu Dou and Tao Yan

    Citation: World Journal of Surgical Oncology 2021 19:120

    Content type: Research

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  17. Endoscopic resection (ER) might affect subsequent laparoscopic gastrectomy (LG) because of the electrical coagulation, but the effect remains controversial. The purpose of this meta-analysis was to analyze the...

    Authors: Dong Peng, Yu-Xi Cheng and Gang Liao

    Citation: World Journal of Surgical Oncology 2021 19:119

    Content type: Research

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  18. The optimal type of operative drainage following pancreaticoduodenectomy (PD) remains unclear. Our objective is to investigate risk associated with closed drainage techniques (passive [gravity] vs. suction) af...

    Authors: Bradley R. Hall, Zachary H. Egr, Robert W. Krell, James C. Padussis, Valerie K. Shostrom, Chandrakanth Are and Bradley N. Reames

    Citation: World Journal of Surgical Oncology 2021 19:118

    Content type: Research

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  19. Radical resection is associated with good prognosis among patients with cT1/T2Nx rectal cancer. However, still some of the patients experienced cancer recurrence following radical resection. This study tried t...

    Authors: I-Li Lai, Jeng-Fu You, Yih-Jong Chern, Wen-Sy Tsai, Jy-Ming Chiang, Pao-Shiu Hsieh, Hsin-Yuan Hung and Yu-Jen Hsu

    Citation: World Journal of Surgical Oncology 2021 19:116

    Content type: Research

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  20. The reliability of the registered ligation level of the inferior mesenteric artery (IMA) in the Swedish Colorectal Cancer Registry has been questioned. The primary aim of this study was to evaluate this parame...

    Authors: Franciska Wikner, Peter Matthiessen, Karl Sörelius, Petter Legrell and Martin Rutegård

    Citation: World Journal of Surgical Oncology 2021 19:115

    Content type: Research

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  21. Due to the high variability of incidence and prevalence of intra-mammary lymph nodes (IMLNs), they might be overlooked during clinical and radiological examinations. Properly characterizing pathological IMLNs ...

    Authors: Tarek Hashem, Ahmed Abdelmoez, Ahmed Mohamed Rozeka and Hazem Abdelazeem

    Citation: World Journal of Surgical Oncology 2021 19:114

    Content type: Research

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  22. The number of young patients diagnosed with breast cancer is on the rise. We studied the rate trend of local recurrence (LR) and regional recurrence (RR) in young breast cancer (YBC) patients and outcomes amon...

    Authors: Yang Li, Su Lu, Yuhan Zhang, Shuaibing Wang and Hong Liu

    Citation: World Journal of Surgical Oncology 2021 19:113

    Content type: Research

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  23. Pancreatic adenocarcinoma (PAAD) is a nonimmunogenic tumor, and very little is known about the relationship between the host immune response and patient survival. We aimed to develop an immune prognostic model...

    Authors: Xiaoqiang Gu, Qiqi Zhang, Xueying Wu, Yue Fan and Jianxin Qian

    Citation: World Journal of Surgical Oncology 2021 19:112

    Content type: Research

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  24. Ezrin-radixin-moesin (ERM) have been explored in many cancer processes. Moesin, as its component, has also been found to play an important role in the prognosis of cancer patients, tumor metastasis, drug resis...

    Authors: Yan-Qi Li, Zhi Zheng, Quan-Xing Liu, Xiao Lu, Dong Zhou, Jiao Zhang, Hong Zheng and Ji-Gang Dai

    Citation: World Journal of Surgical Oncology 2021 19:109

    Content type: Research

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  25. Mastoscopic surgery is proven to have lower incidence of postoperative complications and better postoperative recovery than traditional breast cancer surgery. This study aimed to examine the feasibility of mas...

    Authors: Jiaqi Liu, Heshan Yu, Yuxiao He, Ting Yan, Yu Ding, Jun Chu, Ning Gao, Xiaona Lin, Yanbin Xu and Guijin He

    Citation: World Journal of Surgical Oncology 2021 19:108

    Content type: Research

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  26. Frailty has been shown to be a good predictor of post-operative complications and death in patients undergoing gastrointestinal surgery. The aim of this study was to analyze the differences between frail and n...

    Authors: Manuel Artiles-Armas, Cristina Roque-Castellano, Roberto Fariña-Castro, Alicia Conde-Martel, María Asunción Acosta-Mérida and Joaquín Marchena-Gómez

    Citation: World Journal of Surgical Oncology 2021 19:106

    Content type: Research

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  27. A pathological complete response (pCR) after neoadjuvant chemoradiotherapy (NACRT) ensures long-term survival in esophageal squamous cell carcinoma (ESCC) patients following esophagectomy, but pCR patients are...

    Authors: Yushi Nagaki, Satoru Motoyama, Yusuke Sato, Akiyuki Wakita, Hiromu Fujita, Yoshihiro Sasaki, Kazuhiro Imai and Yoshihiro Minamiya

    Citation: World Journal of Surgical Oncology 2021 19:105

    Content type: Research

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  28. Colon cancer is a commonly worldwide cancer with high morbidity and mortality. Long non-coding RNAs (lncRNAs) are involved in many biological processes and are closely related to the occurrence of colon cancer...

    Authors: Meihong Gao, Yang Guo, Yifu Xiao and Xuequn Shang

    Citation: World Journal of Surgical Oncology 2021 19:104

    Content type: Research

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  29. As LEEP (loop electrosurgical excision procedure) is being increasingly used for the diagnosis and treatment of uterine cervical intraepithelial neoplasia, surgical smoke during LEEP has become an inevitable h...

    Authors: Yi Liu, Menghuang Zhao, Yongqiang Shao, Linzhi Yan and Xueqiong Zhu

    Citation: World Journal of Surgical Oncology 2021 19:103

    Content type: Research

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  30. Laparoscopic surgery has been widely accepted to treat early-stage gastric cancer. However, it is still controversial to perform laparoscopic gastrectomy plus D2 lymphadenectomy for locally advanced gastric ca...

    Authors: Yawei Wang, Yan Wang, Wang Wu, Xiaofang Lu, Tailai An and Jiling Jiang

    Citation: World Journal of Surgical Oncology 2021 19:102

    Content type: Research

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  31. Laparoscopic gastrectomy is an acceptable procedure for early-stage gastric cancer; however, most patients are diagnosed at an advanced stage and older age in Taiwan. The feasibility and safety of applying lap...

    Authors: Si-Yuan Wu, Meng-Hsing Ho, Hao-Ming Chang, Kuo-Feng Hsu, Jyh-Cherng Yu and De-Chuan Chan

    Citation: World Journal of Surgical Oncology 2021 19:101

    Content type: Research

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  32. Down syndrome critical region 1 (DSCR1) is associated with carcinogenesis and tumor growth in several types of malignancy. However, little is known about the role of DSCR1 in CRC progression. The present study...

    Authors: Wen-Xiang Li, Jia-Jia Zheng, Gang Zhao, Chen-Tao LYU and Wei-Qi Lu

    Citation: World Journal of Surgical Oncology 2021 19:100

    Content type: Research

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  33. The American Society of Colon and Rectal Surgeons is suggesting laparoscopic surgeries for colorectal cancer. Conventional perioperative procedures like long preoperative fasting and bowel procedures are not u...

    Authors: Baoxin Wang, Zhenming Wu, Rui Zhang, Yue Chen, Jiuxing Dong and Xiuheng Qi

    Citation: World Journal of Surgical Oncology 2021 19:99

    Content type: Research

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  34. With the development of medical technology, credible options for defect reconstructions after the resection of benign bone tumors of the lower extremities have become a high priority. As the current reconstruc...

    Authors: Lei Wang, Dinghao Luo, Junxiang Wu, Kai Xie, Yu Guo, Yaokai Gan, Wen Wu and Yongqiang Hao

    Citation: World Journal of Surgical Oncology 2021 19:98

    Content type: Research

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  35. Hepatectomy for resectable colorectal liver metastasis (CRLM) is recommended. However, the efficacy of upfront hepatectomy without neoadjuvant chemotherapy (NAC) is unclear due to the uncertainty of perioperat...

    Authors: Kosuke Ono, Tomoyuki Abe, Akihiko Oshita, Yusuke Sumi, Takuya Yano, Hiroshi Okuda, Manabu Kurayoshi, Tsuyoshi Kobayashi, Hideki Ohdan, Toshio Noriyuki and Masahiro Nakahara

    Citation: World Journal of Surgical Oncology 2021 19:97

    Content type: Research

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  36. Colorectal cancer is the third most common type of cancer in the world. We characterize a cohort of patients who survived up to 5 years without recurrence and identify factors predicting the probability of cure.

    Authors: Inge van den Berg, Robert R. J. Coebergh van den Braak, Jeroen L. A. van Vugt, Jan N. M. Ijzermans and Stefan Buettner

    Citation: World Journal of Surgical Oncology 2021 19:96

    Content type: Research

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    The Correction to this article has been published in World Journal of Surgical Oncology 2021 19:159

  37. The feasibility of association liver partition and portal vein ligation for staged hepatectomy (ALPPS) for solitary huge hepatocellular carcinoma (HCC, maximal diameter ≥ 10 cm) remains uncertain. This study a...

    Authors: Zhenfeng Deng, Zongrui Jin, Yonghui Qin, Mingqi Wei, Jilong Wang, Tingting Lu, Ling Zhang, Jingjing Zeng, Li Bao, Ya Guo, Minhao Peng, Banghao Xu and Zhang Wen

    Citation: World Journal of Surgical Oncology 2021 19:95

    Content type: Research

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  38. Frailty is an important consideration for older patients undergoing surgery. We aimed to investigate whether frailty could be a prognostic factor in patients with pancreatic ductal adenocarcinoma who underwent...

    Authors: Shinichiro Yamada, Mitsuo Shimada, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Yu Saito, Katsuki Miyazaki, Takuya Tokunaga and Masaaki Nishi

    Citation: World Journal of Surgical Oncology 2021 19:94

    Content type: Research

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  39. In the last decade, two research groups, the French group by Clough et al. (Br J Surg. 97:1659–65, 2010) and the Chinese one by Li et al. (ISRN Oncol 2013:279013, 2013), proposed two types of classification of...

    Authors: Roberto Cirocchi, Maria Ida Amabile, Alessandro De Luca, Federico Frusone, Domenico Tripodi, Patrizia Gentile, Renata Tabola, Daniele Pironi, Flavio Forte, Massimo Monti, Vito D’Andrea and Salvatore Sorrenti

    Citation: World Journal of Surgical Oncology 2021 19:93

    Content type: Review

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  40. Solitary fibrous tumours (SFTs) in the female genital tract are uncommon. Resection of these tumours is controversial because it can cause life-threatening haemorrhage. We report a case of vulvar SFT that was ...

    Authors: Akimasa Takahashi, Hiroki Nishimura, Tsukuru Amano, Mari Deguchi, Fumi Yoshino, Ryo Kasei, Fuminori Kimura, Suzuko Moritani and Takashi Murakami

    Citation: World Journal of Surgical Oncology 2021 19:92

    Content type: Case report

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  41. Lymph node metastasis is a major prognostic sign of colorectal carcinoma and an important indicator for individualized treatment. M2 macrophages play a key role in carcinogenesis and tumor development by enhan...

    Authors: Yanping Wang, Jikun Wang, Chunyu Yang, Yue Wang, Jinhao Liu, Zuoxiu Shi, Yanlei Chen, Yang Feng, Xueqian Ma and Shifeng Qiao

    Citation: World Journal of Surgical Oncology 2021 19:91

    Content type: Research

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  42. Recent researches have suggested that long noncoding RNA (lncRNA) is involved in the tumorigenesis and development of stomach cancer (SC). This meta-analysis aimed to identify the diagnostic performance of cir...

    Authors: Fang Cao, Yongwei Hu, Zaichang Chen, Wei Han, Weijie Lu, Jianhao Xu, Houzhong Ding and Xiaojun Shen

    Citation: World Journal of Surgical Oncology 2021 19:89

    Content type: Research

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  43. Accumulated evidence has demonstrated that aerobic glycolysis serves as a regulator of tumor cell growth, invasion, and angiogenesis. Herein, we explored the role of protein disulfide isomerase family 6 (PDIA6...

    Authors: Ling Mao, Xiaoweng Wu, Zhengpeng Gong, Ming Yu and Zhi Huang

    Citation: World Journal of Surgical Oncology 2021 19:88

    Content type: Research

    Published on:

  44. The aim of this study was to compare the safety feasibility and safety feasibility of non-intubated (NIVATS) and intubated video-assisted thoracoscopic surgeries (IVATS) during major pulmonary resections.

    Authors: Wenfei Xue, Guochen Duan, Xiaopeng Zhang, Hua Zhang, Qingtao Zhao, Zhifei Xin and Jie He

    Citation: World Journal of Surgical Oncology 2021 19:87

    Content type: Research

    Published on:

  45. Triple-negative breast cancer (TNBC) is a major subtype of breast cancer. Due to the lack of effective therapeutic targets, the prognosis is poor. In order to find an effective target, despite many efforts, th...

    Authors: Qianqian Yuan, Lewei Zheng, Yiqin Liao and Gaosong Wu

    Citation: World Journal of Surgical Oncology 2021 19:86

    Content type: Research

    Published on:

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