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  1. The aim of our study was to observe and compare the curative effect of radiotherapy, chemotherapy, and combined radiotherapy and chemotherapy, as well as comprehensive treatment on superior vena cava syndrome ...

    Authors: Manzhen Sun, Xiaoli Chen, Hongfei Li, Xudong Zhang, Xiaofei Wang, Ruipan Zheng, Guowen Li, Lin Wang and Dianyuan Li

    Citation: World Journal of Surgical Oncology 2021 19:185

    Content type: Research

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  2. Circular RNA low-density lipoprotein receptor-related protein 6 (circLRP6) is considered as an oncogene in many types of cancers. However, the function and mechanisms of circLRP6 in prostate cancer (PCa) tumor...

    Authors: Linghui Qin, Xiaosong Sun, Fei Zhou and Cheng Liu

    Citation: World Journal of Surgical Oncology 2021 19:184

    Content type: Research

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  3. Sentinel lymph node biopsy (SLNB) is the standard approach for the axillary region in early breast cancer patients with clinically negative nodes. The present study investigated patients with false-negative se...

    Authors: Zhu-Jun Loh, Kuo-Ting Lee, Ya-Ping Chen, Yao-Lung Kuo, Wei-Pang Chung, Ya-Ting Hsu, Chien-Chang Huang and Hui-Ping Hsu

    Citation: World Journal of Surgical Oncology 2021 19:183

    Content type: Research

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  4. The prognosis of pancreatic cancer (PC) is extremely poor, and most patients with metastatic PC still receive palliative care. Here, we report the efficacy and safety of FOLFIRINOX (oxaliplatin, irinotecan, le...

    Authors: Beilei Zhang, Fengyan Zhou, Jiaze Hong, Derry Minyao Ng, Tong Yang, Xinyu Zhou, Jieyin Jin, Feifei Zhou, Ping Chen and Yunbao Xu

    Citation: World Journal of Surgical Oncology 2021 19:182

    Content type: Review

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  5. We aimed to develop and validate a radiomics model for differentiating hepatocellular carcinoma (HCC) from focal nodular hyperplasia (FNH) in non-cirrhotic livers using Gd-DTPA contrast-enhanced magnetic reson...

    Authors: Zongren Ding, Kongying Lin, Jun Fu, Qizhen Huang, Guoxu Fang, Yanyan Tang, Wuyi You, Zhaowang Lin, Zhan Lin, Xingxi Pan and Yongyi Zeng

    Citation: World Journal of Surgical Oncology 2021 19:181

    Content type: Research

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  6. There have been many studies on the clinical characteristics of neutrophilic, lymphocytic, and/or eosinophilic pleural effusion. While caring for patients with pleural effusion, we found that histiocytic pleur...

    Authors: Ganghee Chae, Jae-Bum Jun, Hwa Sik Jung, Chui Yong Park, Jin Hyoung Kim, Byung Ju Kang, Hyeon Hui Kang, Seung Won Ra, Kwang Won Seo, Yangjin Jegal, Jong Joon Ahn, Sang Hyuk Park and Taehoon Lee

    Citation: World Journal of Surgical Oncology 2021 19:180

    Content type: Research

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  7. Lymph node metastasis (LNM) is a risk factor for poor long-term outcomes and a prognostic factor for disease-free survival in colon cancer. Preoperative lymph node status evaluation remains a challenge. The pu...

    Authors: Anna Mou, Hang Li, Xiao-li Chen, Yang-hua Fan and Hong Pu

    Citation: World Journal of Surgical Oncology 2021 19:179

    Content type: Research

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  8. Mistletoe extract, used as a complementary chemotherapeutic agent for cancer patients, has anticancer effects against various malignancies. The aim of the present study was to evaluate the effect of mistletoe ...

    Authors: Jeong-Heum Baek, Youngbae Jeon, Kyoung-Won Han, Dong Hae Jung and Kyung-Ok Kim

    Citation: World Journal of Surgical Oncology 2021 19:178

    Content type: Research

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  9. Colon cancer (CC) is a very common gastrointestinal tumor that is prone to invasion and metastasis in the late stage. This study aims to observe the expression of Na+/Ca2+ exchangers (NCXs) and analyze the correl...

    Authors: Zhixiu Xia, Changliang Wang and Hong Zhang

    Citation: World Journal of Surgical Oncology 2021 19:177

    Content type: Research

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  10. Colorectal cancer (CRC) is a common aggressive tumor that poses a heavy burden to human health. An increasing number of studies have reported that circular RNA (circRNA) is involved in the progression of CRC. ...

    Authors: Guojiu Fang, Yibin Wu and Xueli Zhang

    Citation: World Journal of Surgical Oncology 2021 19:176

    Content type: Research

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  11. Repeat hepatectomy and radiofrequency ablation (RFA) are widely used to treat early recurrent hepatocellular carcinoma (RHCC) located in the subcapsular region, but the optimal treatment strategy remains to be...

    Authors: Fuqun Wei, Qizhen Huang, Yang Zhou, Liuping Luo and Yongyi Zeng

    Citation: World Journal of Surgical Oncology 2021 19:175

    Content type: Research

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  12. Despite chemotherapy being a common treatment, an increase in chemoresistance over time is unavoidable. We therefore investigated the role of miR-194-5p in regulating chordoma cell behavior and examined the do...

    Authors: Mengning Xia, Lili Sheng, Wei Qu, Xue Xue, Hucheng Chen, Guoyan Zheng and Weigang Chen

    Citation: World Journal of Surgical Oncology 2021 19:174

    Content type: Research

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  13. Since inflammation and the immune system contribute to the development and progression of malignancies, parameters that reflect a host’s immune-inflammatory status may be useful prognostic indicators of gastri...

    Authors: Hiroyuki Inoue, Toshiyuki Kosuga, Takeshi Kubota, Hirotaka Konishi, Atsushi Shiozaki, Kazuma Okamoto, Hitoshi Fujiwara and Eigo Otsuji

    Citation: World Journal of Surgical Oncology 2021 19:173

    Content type: Research

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  14. The purpose of this letter to the Editor is to report some shortcomings in the statistical analysis and variable grouping in the recent publication of the article “Clinical outcomes of chondroblastoma treated ...

    Authors: Bo-Wen Zheng, Bo-Yv Zheng, Hua-Qing Niu, Xiao-Bin Wang and Jing Li

    Citation: World Journal of Surgical Oncology 2021 19:171

    Content type: Correspondence

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    The original article was published in World Journal of Surgical Oncology 2020 18:47

    The Letter to this article has been published in World Journal of Surgical Oncology 2021 19:172

  15. We retrospectively examined the relationship among skeletal muscle mass index (SMI), prognosis, and chemotherapy side effects in patients with recurrent gastric cancer (RGC).

    Authors: Tomoyuki Matsunaga, Hiroaki Satio, Wataru Miyauchi, Yuji Shishido, Kozo Miyatani, Yuki Murakami, Takehiko Hanaki, Kyoichi Kihara, Manabu Yamamoto, Naruo Tokuyasu, Shuichi Takano, Teruhisa Sakamoto, Toshimichi Hasegawa and Yoshiyuki Fujiwara

    Citation: World Journal of Surgical Oncology 2021 19:170

    Content type: Research

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  16. Interstitial lung disease (ILD) is a rare adverse event in patients receiving adjuvant or neoadjuvant chemotherapy (NAC) for breast cancer. Few studies have reported the frequency of ILD in detail, and only sm...

    Authors: Kenji Tezuka, Kotaro Miura, Yusuke Nakano, Takahiro Ueda, Kyoko Yagyu, Shimako Matsuyama, Masami Shirai, Hiroshi Okuda, Miho Ujikawa and Takayo Ota

    Citation: World Journal of Surgical Oncology 2021 19:169

    Content type: Research

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  17. Sorafenib was reported as a useful adjuvant treatment in patients with hepatocellular carcinoma who underwent surgical resection. However, its therapeutic value remains controversial. This meta-analysis examin...

    Authors: Shenglan Huang, Dan Li, LingLing Zhuang, Liying Sun and Jianbing Wu

    Citation: World Journal of Surgical Oncology 2021 19:168

    Content type: Review

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  18. Elevated plasma D-dimer levels have been reported as an unfavorable prognostic indicator in many solid tumors. However, there are limited relevant studies in pancreatic cancer patients following radical surger...

    Authors: Haoda Chen, Fanlu Li, Siyi Zou, Junjie Xie, Jun Zhang, Xiaxing Deng, Hao Chen and Baiyong Shen

    Citation: World Journal of Surgical Oncology 2021 19:166

    Content type: Research

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  19. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has recently emerged as a viable management option for peritoneal surface malignancy (PSM). CRS and HIPEC is a complex, multidi...

    Authors: Suryanarayana Deo, Mukurdipi Ray, Babul Bansal, Sandeep Bhoriwal, Sushma Bhatnagar, Rakesh Garg, Nishkarsh Gupta, Atul Sharma, Lalit Kumar, Sanjay Thulkar, Ekta Dhamija, Sandeep Mathur and Prasenjit Das

    Citation: World Journal of Surgical Oncology 2021 19:164

    Content type: Research

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  20. Pituitary adenomas are one type of intracranial tumor, which can be divided into microadenoma (≤ 1 cm), macroadenoma (> 1 cm), and giant adenoma (≥ 4 cm) according to their diametral sizes. They are benign, ty...

    Authors: Ding Nie, Qiuyue Fang, Bin Li, Jianhua Cheng, Chuzhong Li, Songbai Gui, Yazhuo Zhang and Peng Zhao

    Citation: World Journal of Surgical Oncology 2021 19:162

    Content type: Review

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  21. Bronchopleural fistula (BPF) refers to an abnormal channel between the pleural space and the bronchial tree. It is a potentially fatal postoperative complication after pulmonary resection and a complex challen...

    Authors: Yongyong Wu, Zhongliang He, Weihua Xu, Guoxing Chen, Zhijun Liu and Ziying Lu

    Citation: World Journal of Surgical Oncology 2021 19:158

    Content type: Case report

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  22. Biologic bone reconstruction in limb salvage surgery for the treatment of malignant bone tumours has always been controversial. The various inactivation methods, their convenience and stability, the curative e...

    Authors: Meitao Xu, Ming Xu, Shuai Zhang, Hanqing Li, A. I. Qiuchi, Xiuchun Yu and Xu Quan Wang

    Citation: World Journal of Surgical Oncology 2021 19:157

    Content type: Research

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  23. Renal cell carcinoma (RCC) is a common malignant tumour of the genitourinary system. We aimed to analyse the potential value of metastasis-related biomarkers, circulating tumour cells (CTCs) and the proliferat...

    Authors: Jinbo Song, Zhe Yu, Bingqi Dong, Mingkai Zhu, Xiaofeng Guo, Yongkang Ma, Shiming Zhao and Tiejun Yang

    Citation: World Journal of Surgical Oncology 2021 19:156

    Content type: Research

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  24. Robot-assisted surgery is increasingly implemented for the resection of colorectal cancer, although the scientific evidence for adopting this technique is still limited. This study’s main objective was to comp...

    Authors: Pedja Cuk, Randi Maria Simonsen, Mirjana Komljen, Michael Festersen Nielsen, Per Helligsø, Andreas Kristian Pedersen, Christian Backer Mogensen and Mark Bremholm Ellebæk

    Citation: World Journal of Surgical Oncology 2021 19:155

    Content type: Research

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  25. The main negative prognostic factors in patients with rectal cancer after radical treatment include regional lymph node involvement, lymphovascular invasion, and perineural invasion. However, some patients sti...

    Authors: Marcin Zeman, Marek Czarnecki, Ewa Chmielik, Adam Idasiak, Władysław Skałba, Mirosław Strączyński, Piotr J. Paul and Agnieszka Czarniecka

    Citation: World Journal of Surgical Oncology 2021 19:154

    Content type: Research

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  26. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are effective routine treatments for colorectal peritoneal metastasis (PM). However, the safety and efficacy of neoadjuvant che...

    Authors: Sicheng Zhou, Yujuan Jiang, Jianwei Liang, Wei Pei and Zhixiang Zhou

    Citation: World Journal of Surgical Oncology 2021 19:151

    Content type: Research

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  27. Approximately 20% of patients with colorectal cancer are initially diagnosed with stage IV disease. This study aims to examine the role of regional lymph node (LN) status in metastatic colorectal cancer (mCRC)...

    Authors: Ya-Ting Kuo, Wen-Sy Tsai, Hsin-Yuan Hung, Pao-Shiu Hsieh, Sum-Fu Chiang, Cheng-Chou Lai, Yih-Jong Chern, Yu-Jen Hsu and Jeng-Fu You

    Citation: World Journal of Surgical Oncology 2021 19:150

    Content type: Research

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  28. The aim of this study was to compare conventional suture with prolonged timing of drainage with quilting suture on the formation of seroma at pectoral area after mastectomy (ME) with sentinel lymph node biopsy...

    Authors: Juan Huang, Shouman Wang, Yuhui Wu, Jian Hai, Jie Mao, Xue Dong and Zhi Xiao

    Citation: World Journal of Surgical Oncology 2021 19:148

    Content type: Research

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  29. Radiomics methods are used to analyze various medical images, including computed tomography (CT), magnetic resonance, and positron emission tomography to provide information regarding the diagnosis, patient ou...

    Authors: Ayten Kayi Cangir, Kaan Orhan, Yusuf Kahya, Hilal Özakıncı, Betül Bahar Kazak, Buse Mine Konuk Balcı, Duru Karasoy and Çağlar Uzun

    Citation: World Journal of Surgical Oncology 2021 19:147

    Content type: Research

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  30. To investigate the predictive value of programmed death-ligand 1 (PD-L1) expression in non-small cell lung cancer (NSCLC) patients treated with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR...

    Authors: Zhiyu Peng, Huahang Lin, Ke Zhou, Senyi Deng and Jiandong Mei

    Citation: World Journal of Surgical Oncology 2021 19:145

    Content type: Review

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  31. Lipoleiomyoma is a rare, benign variant of the commonplace uterine leiomyoma. Unlike leiomyoma, these tumors are composed of smooth muscle cells admixed with mature adipose tissue. While rare, they are most fr...

    Authors: Sara L. Schaefer, Amy L. Strong, Sheena Bahroloomi, Jichang Han, Michella K. Whisman, Jodi M. Wilkowski and Christina V. Angeles

    Citation: World Journal of Surgical Oncology 2021 19:144

    Content type: Case report

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  32. Thyroid neoplasms with follicular architecture can have overlapping morphologic features and pose diagnostic confusion among pathologists. Various immunohistochemical stains have been investigated as potential...

    Authors: Qandeel Sadiq, Radhika Sekhri, Daniel T. Dibaba, Qi Zhao and Shweta Agarwal

    Citation: World Journal of Surgical Oncology 2021 19:143

    Content type: Research

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  33. No universal classification method for intrahepatic cholangiocarcinoma (IHCC) has been reported based on the embryological origin of biliary epithelial cells. The aim of this study was to classify IHCC accordi...

    Authors: Shoko Yamashita, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Yu Saito, Chie Takasu, Shinichiro Yamada, Kazunori Tokuda, Shohei Okikawa, Katsuki Miyazaki, Takeshi Oya, Koichi Tsuneyama and Mitsuo Shimada

    Citation: World Journal of Surgical Oncology 2021 19:142

    Content type: Research

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  34. With the advent of more intensive chemotherapy regimens, neoadjuvant chemoradiotherapy (NACRT) for patients with locally advanced rectal cancer (LARC) has always been questioned due to its inevitable radiation...

    Authors: Huaqin Lin, Lei Wang, Xiaohong Zhong, Xueqing Zhang, Lingdong Shao and Junxin Wu

    Citation: World Journal of Surgical Oncology 2021 19:141

    Content type: Review

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  35. Treatments for metastatic fracture of the humeral shaft continue to evolve as advances are made in both oncological and operative management. The purposes of this study were to critically evaluate the effectiv...

    Authors: Zhiqing Zhao, Zhipeng Ye, Taiqiang Yan, Xiaodong Tang, Wei Guo and Rongli Yang

    Citation: World Journal of Surgical Oncology 2021 19:140

    Content type: Research

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  36. The inflammatory biomarker “C-reactive protein to albumin ratio (CAR)” has been reported to significantly correlate to a variety of human cancers. However, there are conflicting results regarding the prognosti...

    Authors: Chun-Kai Liao, Yen-Lin Yu, Yueh-Chen Lin, Yu-Jen Hsu, Yih-Jong Chern, Jy-Ming Chiang and Jeng-Fu You

    Citation: World Journal of Surgical Oncology 2021 19:139

    Content type: Review

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  37. Mesenchymal sarcomas are tumors that originate from mesenchymal tissue. Most mesenchymal sarcomas can be accurately classified, but some are unclassifiable in clinical practice. Molecular detection methods ena...

    Authors: Weijie Chen, Huimei Wang, Dongxian Jiang, Lijuan Luan, Yuhong Zhou and Yingyong Hou

    Citation: World Journal of Surgical Oncology 2021 19:136

    Content type: Case report

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