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  1. Synovial sarcoma (SS) is a rare soft tissue tumor. Among different anatomical locations where it can be found, gastric localization is a very uncommon one. Based on soft tissue sarcoma guidelines, complete tum...

    Authors: Matteo Rivelli, Eduardo Fernandes, Cristian Conti, Laura Bernardoni, Sara Pecori, Sara Cingarlini and Corrado Pedrazzani

    Citation: World Journal of Surgical Oncology 2021 19:65

    Content type: Case report

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  2. This paper aims to compare the efficacy and safety of recombinant human endostatin combined with chemotherapy in patients with squamous cell lung cancer (SqCLC).

    Authors: Li Feng, Zhicong Wang, Li Jing, Zhiguo Zhou, Shuai Shi, Ruoying Deng, Yibing Liu and Qingju Meng

    Citation: World Journal of Surgical Oncology 2021 19:64

    Content type: Research

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  3. Laparoscopic resection of giant hepatoblastoma (HB) in children has long been a subject of controversy. Here, a new procedure of two-stage laparoscopic resection of giant HB in infants was firstly reported and...

    Authors: Yaohao Wu, Lexiang Zeng, Ronglin Qiu, Jie Zhang, Jianhang Su, Minyi Liao and Xiaogeng Deng

    Citation: World Journal of Surgical Oncology 2021 19:63

    Content type: Research

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  4. Skeletal-related events (SREs) due to bone metastases (BM) significantly impact the morbidity and mortality of cancer patients. The present study sought to investigate clinicopathological characteristics, meta...

    Authors: Georg Herget, Babak Saravi, Eugenia Schwarzkopf, Mara Wigand, Norbert Südkamp, Hagen Schmal, Markus Uhl and Gernot Lang

    Citation: World Journal of Surgical Oncology 2021 19:62

    Content type: Research

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  5. Complete cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is the only curative treatment for pseudomyxoma peritonei (PMP) arising from the appendix. High peritoneal c...

    Authors: Bertrand Trilling, Alexandre Brind’Amour, Raphael Hamad, Jean-Francois Tremblay, Pierre Dubé, Andrew Mitchell and Lucas Sidéris

    Citation: World Journal of Surgical Oncology 2021 19:60

    Content type: Research

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  6. Intrahepatic cholangiocarcinoma (ICC) is a malignant tumor originating from the secondary bile duct and its branch epithelium. Among primary liver tumors, the incidence of ICC is second only to hepatocellular ...

    Authors: Yongwei Zhang, Sihan Chen, Jun Li, Wei Dai and Yeben Qian

    Citation: World Journal of Surgical Oncology 2021 19:59

    Content type: Research

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  7. The associating liver partitioning and portal vein occlusion for staged hepatectomy (ALPPS) procedure is gaining interest because it brings hope to patients who cannot undergo radical surgical resection due to...

    Authors: Ming-Gen Hu, Jin Wang, Zhu-Zeng Yin and Rong Liu

    Citation: World Journal of Surgical Oncology 2021 19:58

    Content type: Case report

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  8. To compare perioperative and oncologic outcomes of open modified ureterosigmoidostomy urinary diversion (OMUUD) and intracorporeal modified ureterosigmoidostomy urinary diversion (IMUUD) following laparoscopic...

    Authors: Duo Zheng, Junyao Liu, Gongjin Wu, Shujun Yang, Chuang Luo, Tianci Du, Yao Luo, Junsheng Bao, Junqiang Tian, Zhiping Wang, Panfeng Shang and Zhongjin Yue

    Citation: World Journal of Surgical Oncology 2021 19:57

    Content type: Research

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  9. Growing evidence for the advantages of robotic pancreatoduodenectomy (RPD) has been demonstrated internationally. However, there has been no structured training program for RPD in Japan. Herein, we present the...

    Authors: Kosei Takagi, Yuzo Umeda, Ryuichi Yoshida, Takahito Yagi, Toshiyoshi Fujiwara, Amer H. Zureikat, Melissa E. Hogg and Bas Groot Koerkamp

    Citation: World Journal of Surgical Oncology 2021 19:55

    Content type: Technical innovations

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  10. This study aimed to investigate the short-term and oncological impact of the Endoscopic Surgical Skill Qualification System (ESSQS) by the Japan Society for Endoscopic Surgery on the operator performing laparo...

    Authors: Keisuke Kazama, Masakatsu Numata, Toru Aoyama, Yosuke Atsumi, Hiroshi Tamagawa, Teni Godai, Hiroyuki Saeki, Yusuke Saigusa, Manabu Shiozawa, Norio Yukawa, Munetaka Masuda and Yasushi Rino

    Citation: World Journal of Surgical Oncology 2021 19:53

    Content type: Research

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  11. Whether a sequential or concurrent regimen of anthracyclines and taxanes is superior for breast cancer is controversial. We compared the efficacy of two regimens in patients with operable breast cancer based o...

    Authors: Wanjing Chen, Qian Tu, Yanfei Shen, Kejun Tang, Mengying Hong and Yong Shen

    Citation: World Journal of Surgical Oncology 2021 19:52

    Content type: Research

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  12. Circular RNAs (circRNAs) are a class of endogenous single-strand RNA transcripts with crucial regulation in human cancers. The objective of this study is to investigate the role of circ_0082182 in CRC and its ...

    Authors: Ruijie Liu, Ping Deng, Yonglian Zhang, Yonglan Wang and Cuiping Peng

    Citation: World Journal of Surgical Oncology 2021 19:51

    Content type: Research

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  13. We invented a new antireflux anastomosis method for use in proximal gastrectomy for adenocarcinoma of the esophagogastric junction (AEG) and named it semi-embedded valve anastomosis (SEV). This study was condu...

    Authors: Yupeng Wu, Shihao Zhang, Liting Wang, Xuya Hu and Zhanxue Zhang

    Citation: World Journal of Surgical Oncology 2021 19:50

    Content type: Research

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  14. Histopathology is a crucial part of diagnosis and treatment guidance of colorectal cancer. In Denmark, it is not routine to biopsy during self-expandable metallic stent (SEMS) placement as a treatment option f...

    Authors: Sigrid Skov Bennedsgaard and Lene Hjerrild Iversen

    Citation: World Journal of Surgical Oncology 2021 19:48

    Content type: Review

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  15. Although completion lobectomy is the treatment of choice for local recurrence of non-small cell lung cancer after segmentectomy, few cases have been reported. We report four patients who underwent completion l...

    Authors: Shigeki Suzuki, Keisuke Asakura, Kyohei Masai, Kaoru Kaseda, Tomoyuki Hishida and Hisao Asamura

    Citation: World Journal of Surgical Oncology 2021 19:47

    Content type: Case report

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  16. Thrombocytopenia was reported both detrimental and advantageous to hepatocellular carcinoma (HCC). However, there is little evidence showing clearly the clinical value of preoperative thrombocytopenia on the s...

    Authors: Wei Peng, Chuan Li, Xiaoyun Zhang, Tianfu Wen and Zheyu Chen

    Citation: World Journal of Surgical Oncology 2021 19:46

    Content type: Research

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  17. Neoadjuvant chemotherapy is an important part of the comprehensive treatment of advanced gastric cancer (GC). The effect of neoadjuvant chemotherapy plays a key role in the prognosis of GC patients. Pathologic...

    Authors: Lin Jiang, Zhiqiang Ma, Xin Ye, Weiming Kang and Jianchun Yu

    Citation: World Journal of Surgical Oncology 2021 19:44

    Content type: Research

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  18. Accurate prediction of postoperative pulmonary function is important for ensuring the safety of patients undergoing radical resection for lung cancer. Dynamic perfusion digital radiography is an excellent and ...

    Authors: Jun Hanaoka, Makoto Yoden, Kazuki Hayashi, Takuya Shiratori, Keigo Okamoto, Ryosuke Kaku, Yo Kawaguchi, Yasuhiko Ohshio and Akinaga Sonoda

    Citation: World Journal of Surgical Oncology 2021 19:43

    Content type: Research

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  19. Xpert Bladder Cancer is a detection method developed in recent years, designed with the functions of integrating sample automatically, nucleic acid amplification, and target sequence detection. It is a urine a...

    Authors: Ye-Ling Liu, Xue-Lin Wang, Xiao-Hui Yang, Xiao-Huan Wu, Guo-Xin He, Li-Min Xie, Xun-Jie Cao and Xu-Guang Guo

    Citation: World Journal of Surgical Oncology 2021 19:42

    Content type: Research

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  20. A peritumoral hypointense rim (PTHR) is sometimes observed around hepatocellular carcinoma (HCC) on T2*-weighted images (T2*WIs). We aimed to investigate the association between the PTHR and histopathologic fi...

    Authors: Yoshinori Tsukahara, Yukinori Okajima, Akira Yamada, Masanobu Momose, Takeshi Uehara, Akira Shimizu, Yuji Soejima and Yasunari Fujinaga

    Citation: World Journal of Surgical Oncology 2021 19:41

    Content type: Research

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  21. Intraoperative urinary collecting system entry (CSE) in robot-assisted partial nephrectomy (RAPN) may cause postoperative urinary leakage and extend the hospitalization. Therefore, identifying and firmly closi...

    Authors: Kenichi Nishimura, Yuichiro Sawada, Naoya Sugihara, Keisuke Funaki, Kanae Koyama, Terutaka Noda, Tetsuya Fukumoto, Noriyoshi Miura, Yuki Miyauchi, Tadahiko Kikugawa and Takashi Saika

    Citation: World Journal of Surgical Oncology 2021 19:40

    Content type: Research

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  22. The involvement of circular RNAs (circRNAs) in tamoxifen (TAM) resistance has been identified. Herein, we aimed to identify the role and novel mechanisms of hsa_circ_0025202 in tamoxifen resistance in breast c...

    Authors: Hongjuan Li, Qing Li and Shan He

    Citation: World Journal of Surgical Oncology 2021 19:39

    Content type: Research

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  23. Robotic and laparoscopic surgery for rectal cancer has been applied in the clinic for decades; nevertheless, which surgical approach has a lower rate of postoperative complications is still inconclusive. There...

    Authors: Bo Tang, Xiong Lei, Junhua Ai, Zhixiang Huang, Jun Shi and Taiyuan Li

    Citation: World Journal of Surgical Oncology 2021 19:38

    Content type: Research

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  24. Denosumab (XgevaTM) is a fully human antibody to RANK-Ligand, an important signal mediator in the pathogenesis of giant cell tumour of bone (GCTB). The use of denosumab in the treatment of GCTB has changed the wa...

    Authors: Wolfram Weschenfelder, John M. Abrahams and Luke J. Johnson

    Citation: World Journal of Surgical Oncology 2021 19:37

    Content type: Case report

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  25. Disease sites of female genital tract cancers of BRCA1/2-associated hereditary breast and ovarian cancer (HBOC) are less understood than non-hereditary cancers. We aimed to elucidate the disease site distribution...

    Authors: Takashi Mitamura, Masayuki Sekine, Masami Arai, Yuka Shibata, Momoko Kato, Shiro Yokoyama, Hiroko Yamashita, Hidemichi Watari, Ichiro Yabe, Hiroyuki Nomura, Takayuki Enomoto and Seigo Nakamura

    Citation: World Journal of Surgical Oncology 2021 19:36

    Content type: Correspondence

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  26. Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) is the first rate-limiting enzyme of the hexosamine biosynthesis pathway (HBP), which plays a pivotal role in the progression of pancreatic ductal adenocar...

    Authors: Yitao Gong, Yunzhen Qian, Guopei Luo, Yu Liu, Ruijie Wang, Shengming Deng, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Weiding Wu and Chen Liu

    Citation: World Journal of Surgical Oncology 2021 19:35

    Content type: Research

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  27. The clinical significance of the geriatric nutritional risk index (GNRI) in locally advanced rectal cancer (LARC) patients undergoing preoperative chemoradiotherapy (CRT) followed by curative surgery has not b...

    Authors: Shozo Ide, Yoshinaga Okugawa, Yusuke Omura, Akira Yamamoto, Takashi Ichikawa, Takahito Kitajima, Tadanobu Shimura, Hiroki Imaoka, Hiroyuki Fujikawa, Hiromi Yasuda, Takeshi Yokoe, Yoshiki Okita, Masaki Ohi and Yuji Toiyama

    Citation: World Journal of Surgical Oncology 2021 19:34

    Content type: Research

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  28. The role of surgical intervention as a treatment for pulmonary metastasis (PM) from hepatocellular carcinoma (HCC) has not been established. In this study, we investigated the clinical outcomes of pulmonary me...

    Authors: Han Pil Lee, Jae Kwang Yun, Hee Suk Jung, Duk Hwan Moon, Geun Dong Lee, Sehoon Choi, Yong-Hee Kim, Dong Kwan Kim, Seung Il Park and Hyeong Ryul Kim

    Citation: World Journal of Surgical Oncology 2021 19:33

    Content type: Research

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  29. Traumatic lymphatic leakage is a rare but potentially life-threatening complication. The purpose of this study was to introduce ultrasound-guided intranodal lymphangiography and embolisation techniques for pos...

    Authors: Xingwei Sun, Feng Zhou, Xuming Bai, Qiang Yuan, Mingqing Zhang, Liang Ma and Yong Jin

    Citation: World Journal of Surgical Oncology 2021 19:32

    Content type: Technical innovations

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  30. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival in selected patients with peritoneal metastasis (PM) from colorectal cancer (CRC). However, little ...

    Authors: Yasuyuki Kamada, Koya Hida, Haruaki Ishibashi, Shouzou Sako, Akiyoshi Mizumoto, Masumi Ichinose, Naveen Padmanabhan, Shinya Yoshida and Yutaka Yonemura

    Citation: World Journal of Surgical Oncology 2021 19:31

    Content type: Research

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  31. The identification of the homogeneous and heterogeneous risk factors for different types of metastases in colorectal cancer (CRC) may shed light on the aetiology and help individualize prophylactic treatment. ...

    Authors: Tianwen Luo, Yutong Wang, Xuefeng Shan, Ye Bai, Chun Huang, Guangcan Li and Hongmei Wang

    Citation: World Journal of Surgical Oncology 2021 19:30

    Content type: Research

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  32. This study aimed to evaluate the computed tomography (CT) features of solitary pulmonary nodule (SPN), which can be a non-invasive diagnostic tool to differentiate between primary lung cancer (LC) and solitary...

    Authors: Jong Eun Lee, Won Gi Jeong and Yun-Hyeon Kim

    Citation: World Journal of Surgical Oncology 2021 19:28

    Content type: Research

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  33. The aim of this study was to establish a regression equation model of serum bone metabolism markers. We analyzed the diagnostic value of bone metastases in lung cancer and provided laboratory evidence for the ...

    Authors: Zhongliang Zhu, Guangyu Yang, Zhenzhen Pang, Jiawei Liang, Weizhong Wang and Yonglie Zhou

    Citation: World Journal of Surgical Oncology 2021 19:27

    Content type: Research

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  34. Although the morbidity of gastric cancer has decreased, the incidence of adenocarcinoma of the esophagogastric junction (AEG) is increasing. Furthermore, no consensus exists on which surgical approach should b...

    Authors: Wei Pang, Gang Liu, Yan Zhang, Yun Huang, Xinpu Yuan, Zhanwei Zhao and Chaojun Zhang

    Citation: World Journal of Surgical Oncology 2021 19:26

    Content type: Research

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  35. An emerging prediction tool, the Controlling Nutritional Status (CONUT) score, has shown good assessment ability of postoperative outcomes in cancer patients. This study evaluated the role of the preoperative ...

    Authors: Yun Qian, Huaying Liu, Junhai Pan, Weihua Yu, Jiemin Lv, Jiafei Yan, Jiaqi Gao, Xianfa Wang, Xiaolong Ge and Wei Zhou

    Citation: World Journal of Surgical Oncology 2021 19:25

    Content type: Research

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  36. Multiple myeloma causes different types of renal injury. C3 glomerulonephritis (C3GN) is characterised by an abnormal deposition of complement C3 in the glomeruli due to abnormal activation of the alternative ...

    Authors: Junhui Xu, Xiaojuan Yu, Suxia Wang, Miao Yan, Mangju Wang, Jinping Ou, Lihong Wang, Huihui Liu and Xinan Cen

    Citation: World Journal of Surgical Oncology 2021 19:24

    Content type: Case report

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  37. The use of 3-dimensional (3D) endoscopic thyroidectomy (ET) has been increasing, but its feasibility and safety have not been well documented for thyroidectomy. Hence, to systematically investigate the compara...

    Authors: Zigao Huang, Haiquan Qin, Jiankun Liao, Linghou Meng, Yongjie Qin, Baojia Li, Hao Lai and Xianwei Mo

    Citation: World Journal of Surgical Oncology 2021 19:23

    Content type: Review

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  38. Peutz–Jeghers syndrome (PJS) is a very rare autosomal dominant genetic disorder characterized by hamartomatous polyps in the gastrointestinal tract and hyperpigmentation of the lips, hands, and feet. The hamar...

    Authors: Masaaki Yamamoto, Kazuya Iwamoto, Rei Suzuki, Yosuke Mukai, Tomohira Takeoka, Kei Asukai, Naoki Shinno, Hisashi Hara, Takashi Kanemura, Nozomu Nakai, Shinichiro Hasegawa, Keijiro Sugimura, Naotsugu Haraguchi, Junichi Nishimura, Hiroshi Wada, Hidenori Takahashi…

    Citation: World Journal of Surgical Oncology 2021 19:22

    Content type: Case report

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  39. Colorectal cancer patients undergoing surgical resection are at increased short-term risk of post-operative adverse events. However, specific predictors for long-term major adverse cardiac and cerebrovascular ...

    Authors: Chieh Yang Koo, Bee-Choo Tai, Dedrick Kok Hong Chan, Li Ling Tan, Ker Kan Tan and Chi-Hang Lee

    Citation: World Journal of Surgical Oncology 2021 19:21

    Content type: Research

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  40. As a common malignancy, gastric cancer (GC) remains an important threat to human’s health. The incidence of synchronous multiple gastric cancer (SMGC) has increased obviously with technical advances of endosco...

    Authors: Liang Chen, Chao Yue, Gang Li, Xuezhi Ming, Rongmin Gu, Xu Wen, Bin Zhou, Rui Peng, Wei Wei and Huanqiu Chen

    Citation: World Journal of Surgical Oncology 2021 19:20

    Content type: Research

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  41. Primary hyperparathyroidism is an endocrine pathology that affects calcium metabolism. Patients with primary hyperparathyroidism have high concentrations of serum calcium or high concentrations of parathyroid ...

    Authors: Alessandro Galani, Riccardo Morandi, Mira Dimko, Sarah Molfino, Carla Baronchelli, Silvia Lai, Federico Gheza, Carlo Cappelli and Claudio Casella

    Citation: World Journal of Surgical Oncology 2021 19:19

    Content type: Research

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  42. The aim of this study was to investigate the overall survival (OS) between proximal gastric cancer (PG) and distal gastric cancer (DG) patients after gastrectomy.

    Authors: Jiaming Xue, Huiliang Yang, Shanshan Huang, Tingting Zhou, Xiangwen Zhang and Guo Zu

    Citation: World Journal of Surgical Oncology 2021 19:17

    Content type: Review

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  43. Oral squamous cell carcinoma (OSCC) accounts for more than 90% of the oral carcinomas and has a high fatality rate. This study aimed to identify potentially diagnostic biomarkers of OSCC through integrated ana...

    Authors: Le Chen and Dong Wang

    Citation: World Journal of Surgical Oncology 2021 19:16

    Content type: Research

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  44. Pancreatic serous cystadenoma (SCA) is a benign, cystic lesion with an indolent growth pattern. Complications such as spontaneous hemorrhage or malignant transformation from SCA are extremely rare. Our case re...

    Authors: Da Eun Cha, Callie Horn and Michael Passeri

    Citation: World Journal of Surgical Oncology 2021 19:15

    Content type: Case report

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