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  1. Gastric cancer (GC), a common malignancy of the human digestive system, represents the second leading cause of cancer-related deaths worldwide. Early detection of GC has a significant impact on clinical outcom...

    Authors: Dinglian Mei, Yalong Qi, Yuanyuan Xia, Jun Ma, Hao Hu, Jun Ai, Liqiang Chen, Ning Wu and Daixiang Liao

    Citation: World Journal of Surgical Oncology 2021 19:311

    Content type: Research

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  2. D3 or complete mesocolic excision (CME) surgery has become a common surgical procedure for the treatment of colon cancer metastasis. Clinical misuse and overuse of lymph node dissection bring unnecessary burde...

    Authors: Jiangrui Liu, Yibin Su, Xing Liu, Jinfu Zhuang, Yuanfeng Yang and Guoxian Guan

    Citation: World Journal of Surgical Oncology 2021 19:310

    Content type: Research

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  3. Ectopic pancreas is basically a benign disease and is not always necessary to be removed. However, all types of neoplasms occurring in the normal pancreas such as ductal adenocarcinomas and intraductal papilla...

    Authors: Naoko Nambu, Takashi Yamasaki, Nami Nakagomi, Tsutomu Kumamoto, Tatsuro Nakamura, Akio Tamura, Toshihiko Tomita, Hiroto Miwa, Hisashi Shinohara and Seiichi Hirota

    Citation: World Journal of Surgical Oncology 2021 19:309

    Content type: Case report

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  4. Rectal cancer, one of most common neoplasms, is characterized by an overall survival rate exceeding 60%. Nonetheless, local recurrence (LR) following surgery for rectal cancer remains a formidable clinical pro...

    Authors: Michal Jankowski, Wojciech M. Wysocki, Manuela Las-Jankowska, Karol Tkaczyński, Dorian Wiśniewski, Dariusz Bała and Wojciech Zegarski

    Citation: World Journal of Surgical Oncology 2021 19:308

    Content type: Research

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  5. To evaluate the immune function of gastric cancer patients after single-incision laparoscopic distal gastrectomy (SIDG) or multiport laparoscopic distal gastrectomy (MLDG) guided by enhanced recovery after sur...

    Authors: Junfeng Zhou, Sheng Lin, Sida Sun, Chengying Zheng, Jiaxing Wang and Qingliang He

    Citation: World Journal of Surgical Oncology 2021 19:307

    Content type: Research

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  6. Sentinel lymph node biopsy is the gold standard surgical technique for axillary staging in patients with clinically node-negative. However, it is still uncertain what is the optimal number of sentinel lymph no...

    Authors: Calogero Cipolla, Antonio Galvano, Salvatore Vieni, Federica Saputo, Simona Lupo, Mario Latteri, Giuseppa Graceffa and Maria Rosaria Valerio

    Citation: World Journal of Surgical Oncology 2021 19:306

    Content type: Research

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  7. Some clinical researchers have reported that patients with cCR (clinical complete response) status after neoadjuvant chemoradiotherapy (nCRT) could adopt the watch-and-wait (W&W) strategy. Compared with total ...

    Authors: Guilin Yu, Wenqing Lu, Zhouguang Jiao, Jun Qiao, Shiyang Ma and Xin Liu

    Citation: World Journal of Surgical Oncology 2021 19:305

    Content type: Research

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  8. The characteristics of immune-related long non-coding ribonucleic acids (ir-lncRNAs), regardless of their specific levels, have important implications for the prognosis of patients with bladder cancer.

    Authors: Zhenzhen Gao, Dongjuan Wu, Wenwen Zheng, Taohong Zhu, Ting Sun, Lianhong Yuan, Faming Fei and Peng Fu

    Citation: World Journal of Surgical Oncology 2021 19:304

    Content type: Research

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  9. The role of unresected small lymph nodes (LNs) which may contain metastases for thoracic esophageal squamous cell carcinoma (TESCC) has not been addressed. The aim of the study was to investigate the role of u...

    Authors: Yi Wang, Ping Xiao, Ningjing Yang, Xiang Wang, Ke Ma, Lei Wu, Wei Zhang, Xiang Zhuang, Tianpeng Xie, Qiang Fang, Mei Lan, Qifeng Wang and Lin Peng

    Citation: World Journal of Surgical Oncology 2021 19:303

    Content type: Research

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  10. Prokineticin 1 (PROK1) was reported as an angiogenic factor, which is associated with tumor progression, cell invasion, and metastasis in colorectal cancer. Although the association between PROK1 expression in...

    Authors: Noriyuki Tagai, Takanori Goi, Michiaki Shimada and Hidetaka Kurebayashi

    Citation: World Journal of Surgical Oncology 2021 19:302

    Content type: Research

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  11. The effects and safety of laparoscopic nerve‑sparing radical hysterectomy (LNSRH) and laparoscopic radical hysterectomy (LRH) in cervical cancer treatment remain unclear. This article aims to evaluate the role...

    Authors: Linlin Ma, Qiwei Li, Ying Guo, Xiaoyu Tan, Mengying Wang and Qi Qi

    Citation: World Journal of Surgical Oncology 2021 19:301

    Content type: Research

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  12. Tumor-infiltrating lymphocytes (TILs) are major participants in the tumor microenvironment. The prognostic value of TILs in patients with pancreatic cancer is still controversial.

    Authors: Lingyu Hu, Mingyuan Zhu, Yiyu Shen, Zhengxiang Zhong and Bin Wu

    Citation: World Journal of Surgical Oncology 2021 19:300

    Content type: Research

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  13. Emerging evidence reveals that the initiation and development of human cancers, including colorectal cancer (CRC), are associated with the deregulation of circular RNAs (circRNAs). Our study intended to disclo...

    Authors: Lei Zhang, Ranran Yu, Chunhua Li, Yu Dang, Xiaoyu Yi and Lei Wang

    Citation: World Journal of Surgical Oncology 2021 19:299

    Content type: Research

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  14. Although pembrolizumab has shown clinical benefit in patients with small-cell lung cancer (SCLC), its actual efficacy in combination with a conventional chemotherapy drug has not been determined. We performed ...

    Authors: Qiangyun Liu, Yixuan Zhang, Miaowen Liu, Ruoxin Xu, Fengming Yi, Yiping Wei, Shuqiang Zhu and Wenxiong Zhang

    Citation: World Journal of Surgical Oncology 2021 19:298

    Content type: Review

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  15. Inflammation markers have an important effect on tumor proliferation, invasion, and metastasis. Oligometastatic disease (OMD) is an intermediate state between widespread metastases and locally confined disease...

    Authors: Xiaojuan Huang, Jin Cui, Xiaohui Li, Chao Liu, Jujie Sun and Jinbo Yue

    Citation: World Journal of Surgical Oncology 2021 19:297

    Content type: Research

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  16. To investigate the lymph node metastasis pattern and significance of dissection of the left gastric artery lymph nodes in radical en bloc esophagectomy for esophageal squamous carcinomas based on the lymphatic...

    Authors: Xiu-Mei Deng, Tian-Yu Zhu, Guo-Jun Wang, Bu-Lang Gao, Jing-Tao Wang, Rui-Xin Li, Yun-Fei Zhang and Heng-Xuan Ding

    Citation: World Journal of Surgical Oncology 2021 19:296

    Content type: Research

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  17. Laennec’s capsule has been found for about 200 years. However, laparoscopic anatomical right and left hemihepatectomy (LARH and LALH) using Laennec’s approach are rarely reported.

    Authors: Wei Hu, Gongming Zhang, Meng Chen, Chengcheng Zhong, Mingxu Li, Xitai Sun, Kai Li and Zhong Wang

    Citation: World Journal of Surgical Oncology 2021 19:295

    Content type: Research

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  18. Breast cancer (BC) has a high incidence and mortality rate in females. Its conventional clinical characteristics are far from accurate for the prediction of individual outcomes. Therefore, we aimed to develop ...

    Authors: Menglin He, Cheng Hu, Jian Deng, Hui Ji and Weiqian Tian

    Citation: World Journal of Surgical Oncology 2021 19:294

    Content type: Research

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  19. Transcatheter arterial chemoembolization has been widely used in patients with hepatocellular carcinoma. However, double blood supply and the existence of portal vein tumor thrombus influence the efficacy of t...

    Authors: Zhiying Shao, Xin Liu, Chanjuan Peng, Liping Wang and Dong Xu

    Citation: World Journal of Surgical Oncology 2021 19:293

    Content type: Review

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  20. Axillary lymph node involvement is one important prognostic factor in breast cancer, but the way to access this information has been modified over the years. This study evaluated if axillary ultrasound (US) co...

    Authors: Isabela Panzeri Carlotti Buzatto, Francisco José Cândido dos Reis, Jurandyr Moreira de Andrade, Tamara Cristina Gomes Ferraz Rodrigues, Jéssica Maria Camargo Borba, Amanda Homse Netto, Marina Sconzo Polydoro and Daniel Guimarães Tiezzi

    Citation: World Journal of Surgical Oncology 2021 19:292

    Content type: Research

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  21. The incidence of remnant gastric cancer (RGC) after distal gastrectomy is 1–5%. However, as the survival rate of patients with gastric cancer improves due to early detection and treatment, more patients may de...

    Authors: Kentaro Matsuo, Sang-Woong Lee, Ryo Tanaka, Yoshiro Imai, Kotaro Honda, Kohei Taniguchi, Hideki Tomiyama and Kazuhisa Uchiyama

    Citation: World Journal of Surgical Oncology 2021 19:291

    Content type: Research

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  22. To evaluate the usefulness of surveillance-abbreviated magnetic resonance imaging (AB-MRI) for the detection of ipsilateral local tumor recurrence (LTR) in patients who underwent oncoplastic breast-conserving ...

    Authors: Mi Young Kim, Young Jin Suh and Yeong Yi An

    Citation: World Journal of Surgical Oncology 2021 19:290

    Content type: Research

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  23. Myeloid sarcoma (MS) is a tumor secondary to myeloid leukemia that consists of immature granulocytes with or without mature granulocytes and is a rare extramedullary manifestation of acute myeloid leukemia (AML).

    Authors: Chengmin Huang, Shengqi Fei, Jiang Yao, Panpan Chen, Jiaqing Luo, Yaqi Wang, Jie Li and Weilan Wang

    Citation: World Journal of Surgical Oncology 2021 19:289

    Content type: Case report

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  24. Minimally invasive surgery for early cervical cancer is debated. We developed this new vaginal-assisted gasless laparoendoscopic single-site radical hysterectomy for early cervical cancer, and we aimed to eval...

    Authors: Xiaojuan Wang, Junwei Li, Keqin Hua and Yisong Chen

    Citation: World Journal of Surgical Oncology 2021 19:288

    Content type: Research

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  25. lncRNA-CDKN2B antisense RNA 1 (ANRIL) and SRY-box transcription factor 9 (SOX9) has abnormal expression in many tumors including glioma, but the underlying molecular mechanism is unclear. This study set out to...

    Authors: Youlu Sun, Yuesong Jing and Yuxin Zhang

    Citation: World Journal of Surgical Oncology 2021 19:287

    Content type: Research

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  26. To investigate the effect of Helicobacter pylori (H. pylori) eradication on the prognosis of postoperative early gastric cancer (EGC).

    Authors: Liang Wang, Jinfeng Wang, Sha Li, Fei Bai, Hailong Xie, Hanguo Shan, Zhuo Liu, Tiexiang Ma, Xiayu Tang, Haibing Tang, Ang Qin, Sanlin Lei and Chaohui Zuo

    Citation: World Journal of Surgical Oncology 2021 19:285

    Content type: Research

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  27. To determine the potential of the combination of DCE-MRI imaging method with DWI and serum CA125 and CA199 levels in the evaluation of the efficacy of neoadjuvant chemotherapy in breast cancer patients.

    Authors: Jun Zhang, Yongbo Huang, Jianghui Chen, Xia Wang and Hongyu Ma

    Citation: World Journal of Surgical Oncology 2021 19:284

    Content type: Research

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  28. To study the clinical value of miR-135 and miR-20a combined with multi-detector computed tomography (MDCT) in the diagnosis of gastric cancer (GC).

    Authors: Wenwen Han, Xiangzhen Bu, Yanli Liu, Fang Liu, Yujie Ren, Yongsheng Cui and Shuhong Kong

    Citation: World Journal of Surgical Oncology 2021 19:283

    Content type: Research

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  29. To explore the clinical outcomes and effect on intraoperative blood loss and postoperative pain of patients undergoing the retroperitoneal laparoscopic partial nephrectomy (RLPN) for complex renal tumors.

    Authors: Yansong Guo, Qian Xu, Baochun Chen, Lifeng Liu, Yuanyuan Wang, Ai Zhu and Longjiang Tian

    Citation: World Journal of Surgical Oncology 2021 19:282

    Content type: Research

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  30. The administration of postoperative radiotherapy remains controversial in pN1 oral cavity cancer patients without extranodal extension. The aim is to determine whether postoperative radiotherapy reduces the ne...

    Authors: Tsung-You Tsai, Yenlin Huang, Andrea Iandelli, Shiao-Fwu Tai, Shao-Yu Hung, Huang-Kai Kao and Kai-Ping Chang

    Citation: World Journal of Surgical Oncology 2021 19:279

    Content type: Research

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  31. We conducted a study to explore the relationship between pathological cytomorphologic features and the percentage of anaplastic lymphoma kinase (ALK)-positive cells to better predict pulmonary adenocarcinoma p...

    Authors: Fenge Jiang, Congcong Wang, Ping Yang, Ping Sun and Jiannan Liu

    Citation: World Journal of Surgical Oncology 2021 19:278

    Content type: Research

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  32. Skin autofluorescence (SAF) reflects accumulation of advanced glycation end-products (AGEs). The aim of this study was to evaluate predictive usefulness of SAF measurement in prediction of acute kidney injury ...

    Authors: Maciej Krasnodębski, Karolina Grąt, Marcin Morawski, Jan Borkowski, Piotr Krawczyk, Andriy Zhylko, Michał Skalski, Piotr Kalinowski, Krzysztof Zieniewicz and Michał Grąt

    Citation: World Journal of Surgical Oncology 2021 19:276

    Content type: Research

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  33. Squamous cell carcinoma (SCC) is a disease with distinct management complexities as it displays a remarkably heterogeneous molecular subtype. However, the landscape of angiogenesis for SCC is not fully investi...

    Authors: Fanglu Qin, Shenghua Lin, Kun Deng, Junqi Qin, Zhanyu Xu, Liqiang Yuan, Jiangbo Wei, Yu Sun, Tiaozhan Zheng and Shikang Li

    Citation: World Journal of Surgical Oncology 2021 19:275

    Content type: Research

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  34. Dihydropyrimidinase like 2 (DPYSL2) has been linked to tumor metastasis. However, the function of DPSY2L in lung adenocarcinoma (LUAD) is yet to be explored.

    Authors: Yang-Jie Wu, Ai-Tao Nai, Gui-Cheng He, Fei Xiao, Zhi-Min Li, San-Yuan Tang, Yan-Ping Liu and Xiao-Hong Ai

    Citation: World Journal of Surgical Oncology 2021 19:274

    Content type: Research

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  35. Breast cancer is the most common malignancy in women. Cancer driver gene-mediated alterations in the tumor microenvironment are critical factors affecting the biological behavior of breast cancer. The purpose ...

    Authors: Xiao-wei Du, Gao Li, Juan Liu, Chun-yan Zhang, Qiong Liu, Hao Wang and Ting-song Chen

    Citation: World Journal of Surgical Oncology 2021 19:273

    Content type: Research

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  36. To evaluate whether the addition of taxanes to platinum and fluoropyrimidines in adjuvant chemotherapy would result in longer survival than platinum plus fluoropyrimidines in gastric cancer patients who receiv...

    Authors: Lili Wu, Ying Feng, Zhijun Wu, Hui Xu, Cheng Zhang, Jie Ning, Rong Wang, Jianqiong Chen, Minmin Xie, Yi Zhang, Lijia Bu, Jiqing Hao and Tai Ma

    Citation: World Journal of Surgical Oncology 2021 19:272

    Content type: Research

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  37. The safety and efficacy of indocyanine green (ICG) imaging navigational laparoscopic gastrectomy remain controversial. This study is to evaluate the short-term and long-term outcomes of ICG-guided laparoscopic...

    Authors: Xiaofeng Lu, Song Liu, Xuefeng Xia, Feng Sun, Zhijian Liu, Jiafeng Wang, Xianghui Li, Zhengyang Yang, Xing Kang, Shichao Ai and Wenxian Guan

    Citation: World Journal of Surgical Oncology 2021 19:271

    Content type: Research

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  38. The abnormal expression of microRNA (miRNA) has been proved to be closely related to the occurrence and progression of tumors. A unique expression of multiple miRNAs has been found in different types of tumors...

    Authors: Qizhi Zhang, Ying Wang, Yinting Zhou, Qiujuan Zhang and Chuan Xu

    Citation: World Journal of Surgical Oncology 2021 19:270

    Content type: Research

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  39. Pedunculated polyps are more likely to be amenable to complete resection than non-pedunculated early colorectal cancers and rarely require additional surgery. We encountered a patient with a pedunculated early...

    Authors: Hiroka Kondo, Shimpei Ogawa, Takeshi Ohki, Yoshiko Bamba, Yuka Kaneko, Kurodo Koshino, Ryosuke Nakagawa, Kimitaka Tani, Fumi Maeda, Hisako Aihara, Fumiaki Tokito, Shuji Fujikawa, Tomoko Yamamoto, Yoji Nagashima, Yuji Inoue, Michio Itabashi…

    Citation: World Journal of Surgical Oncology 2021 19:269

    Content type: Case report

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  40. Circular RNA 0029803 (circ_0029803) was found to be upregulated in colorectal cancer (CRC) tissues, but its function and underlying molecular mechanism are not studied in CRC.

    Authors: Linfei Huang, Lei Zhu, Sheng Pan, Jing Xu, Miao Xie, Wei Wang and Ganlin Xia

    Citation: World Journal of Surgical Oncology 2021 19:268

    Content type: Research

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  41. Extraskeletal osteosarcoma (ESOS) is a rare mesenchymal malignancy, which produces osteoid, bone, or chondroid material and is located in the soft tissue without attachment to skeletal bones and periosteum. On...

    Authors: Xinyang Nie, Weihua Fu, Chuan Li, Li Lu and Weidong Li

    Citation: World Journal of Surgical Oncology 2021 19:267

    Content type: Case report

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  42. MicroRNA-140 (miR-140) is one of the most widely investigated miRNAs in cell carcinogenesis and cancer development. Despite present proposals of employing miR-140 as a candidate biomarker for cancer prognosis,...

    Authors: Mengxia Zheng, Jingting Liu, Chunyan Meng, Kaifeng Tang and Jianhua Liao

    Citation: World Journal of Surgical Oncology 2021 19:266

    Content type: Review

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  43. Colorectal cancer (CRC) is one of the most frequent neoplasms in the world. Based on the emerging role of noncoding RNAs, particularly circular RNAs in pathogenesis of cancers, we designed this study to inspec...

    Authors: Sepideh Kadkhoda, Reza Taslimi, Farshid Noorbakhsh, Farzaneh Darbeheshti, Javad Tavakkoly Bazzaz, Soudeh Ghafouri-Fard and Abbas Shakoori

    Citation: World Journal of Surgical Oncology 2021 19:265

    Content type: Research

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  44. Studies on PD-L1 expression in breast cancer have gained importance in recent years, especially in triple-negative breast cancer (TNBC). Our aim was to analyze the differential expression of PD-L1 to explore i...

    Authors: Gizem Oner, Semen Önder, Hüseyin Karatay, Naziye Ak, Mustafa Tükenmez, Mahmut Müslümanoğlu, Abdullah İğci, Ahmet Dincçağ, Vahit Özmen, Adnan Aydiner, Ekrem Yavuz and Neslihan Cabioğlu

    Citation: World Journal of Surgical Oncology 2021 19:264

    Content type: Research

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  45. Frozen section (FS) pathology has multiple limitations, and different institutions report variable experiences with the use of FS for diagnosis of tumor involvement. We aimed to compare the FS accuracy with th...

    Authors: Zahra Mehdipour Namdar, Navid Omidifar, Peyman Arasteh, Majid Akrami, Sedigheh Tahmasebi, Aida Salehi Nobandegani, Sogol Sedighi, Vahid Zangouri and Abdolrasoul Talei

    Citation: World Journal of Surgical Oncology 2021 19:261

    Content type: Research

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