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  1. Liver cancer is one of the most common tumors with the seventh-highest incidence and the third-highest mortality. Many studies have shown that small extracellular vesicles (sEVs) play an important role in live...

    Authors: Wei Dong, Zeyu Xia, Zehua Chai, Zhidong Qiu, Xuehong Wang, Zebin Yang, Junnan Wang, Tingrui Zhang, Qinqin Zhang and Junfei Jin
    Citation: World Journal of Surgical Oncology 2022 20:387
  2. Pulmonary sarcomatoid carcinoma (PSC) is a rare and unconventional non-small-cell lung cancer (NSCLC) that appears to be aggressive, with a poor prognosis and response to conventional treatment. Approximately ...

    Authors: Ying Wu, Zhecheng Yan, Juan Pan, Xiaona Chang, Bo Huang, Danju Luo, Rui Meng, Heshui Shi, Jun Fan and Xiu Nie
    Citation: World Journal of Surgical Oncology 2022 20:386
  3. Laparoscopic liver resections (LLR) have been shown a treatment approach comparable to open liver resections (OLR) in hepatocellular carcinoma (HCC). However, the influence of procedural type on body compositi...

    Authors: Ruoh-Yun Gau, Hsin-I Tsai, Ming-Chin Yu, Kun-Ming Chan, Wei-Chen Lee, Haw-En Wang, Sheng-Fu Wang, Mei-Ling Cheng, Chien-Chih Chiu, Hsin-Yi Chen and Chao-Wei Lee
    Citation: World Journal of Surgical Oncology 2022 20:385
  4. Multiple treatment options at glioblastoma progression exist, including reintervention, reirradiation, additional systemic therapy, and novel strategies. No alternative has been proven to be superior in terms ...

    Authors: Víctor González, Marta Brell, José Fuster, Lesmes Moratinos, Daniel Alegre, Sofía López and Javier Ibáñez
    Citation: World Journal of Surgical Oncology 2022 20:384
  5. The switch/sucrose nonfermentable (SWI/SNF) complex is an evolutionarily conserved chromatin remodeling complex that displays dysfunction in many tumors, especially undifferentiated carcinoma. Cancer stem cell...

    Authors: Zhenkun Zhang, Qiujing Li, Shanshan Sun, Zhe Li, Zheng Guo Cui, Menglan Zhang, Qian Liu, Yujie Zhang, Sili Xiong and Shukun Zhang
    Citation: World Journal of Surgical Oncology 2022 20:383
  6. CD97 is the most widely expressed G protein-coupled receptor in the epidermal growth factor seven-span transmembrane family. It plays a vital role in cell adhesion, migration, and cell connection regulation. W...

    Authors: Qiuming Su, Lu Li, Xiaokai Li, Wang Li, Xibing Zhang, Yun Dong, Lei Han, Duo Wang and Jianghua Ran
    Citation: World Journal of Surgical Oncology 2022 20:382
  7. An increasing number of studies have shown that microRNAs play an important role in the occurrence and development of small cell lung cancer, which mainly manifest as oncogenic and tumor inhibition. Therefore,...

    Authors: Jun Peng, Jinfeng Liu, Huining Liu, Yan Huang and Yingchun Ren
    Citation: World Journal of Surgical Oncology 2022 20:381
  8. To screen out potential biomarkers by analyzing fundamental nutrients in the bronchoalveolar lavage fluid (BALF) before confirming the lung cancer.

    Authors: Xiaojun Sun, Mengmin Xu, Liren Ding, Guobiao Yang, Jianlong Kong, Yafang Zhu, Xuefang Chen, Liang Xu, Yisha Shan and Yupin Xu
    Citation: World Journal of Surgical Oncology 2022 20:380
  9. Current research has shown a link between ABO blood group and many diseases. The purpose of this study aimed to investigate the influence of the ABO blood group on the risk of developing different pathological...

    Authors: Haotian Yang, Xianjun Zeng, Yu Zhang, Weilai Tong, Geliang Yao, Chunyu Lan, Jiaming Liu, Zhili Liu and Nanshan Zhong
    Citation: World Journal of Surgical Oncology 2022 20:379
  10. Excessive preoperative blood orders frequently occur during the preoperative planning of resections of sarcomas. We aimed to develop a prediction score model that would be able to identify a patient cohort in ...

    Authors: Farhad Farzaliyev, Hans-Ulrich Steinau, Atajan Halmyradov, Eugen Malamutmann, Arie Sleutel, Claudius Illg and Lars Erik Podleska
    Citation: World Journal of Surgical Oncology 2022 20:378
  11. Hepatocellular carcinoma (HCC) is still fatal even after surgical resection. The purpose of this study was to analyze the prognostic factors of 5-year survival rate and to establish a model to identify HCC pat...

    Authors: Jie Hu, Ni Gong, Dan Li, Youyuan Deng, Jiawei Chen, Dingan Luo, Wei Zhou and Ke Xu
    Citation: World Journal of Surgical Oncology 2022 20:377
  12. GISTs are rare tumors but the most frequent mesenchymal tumors of the digestive tract. Diagnosis and treatment are challenging in low-income countries due to relatively poor access to immunohistochemistry and ...

    Authors: Dansou Gaspard Gbessi, Freddy Houéhanou Rodrigue Gnangnon, Aboudou Raïmi Kpossou, Pacifique Prudent Gbetchedji, Falilatou Seidou, Yacoubou Imorou Souaïbou, Setondji Gilles Roger Attolou, Ismaïl Lawani, Marie-Christel Laleye, Flore Gangbo, Francis Moïse Dossou, Jean Sehonou and Delphin Kuassi Mehinto
    Citation: World Journal of Surgical Oncology 2022 20:247
  13. A new approach for laparoscopic gastric dissociation in minimally invasive esophagectomy (MIE) was attempted. This study aimed to evaluate the short-term outcomes, safety, and efficacy of two-port laparoscopy ...

    Authors: Huaguang Pan, Renquan Zhang, Ao Li, Hanlin Fang, Hao Zheng, Menglong Jiang, Wei Ge, Fan Zhou, Xiancheng Liu and Chuntong Yin
    Citation: World Journal of Surgical Oncology 2022 20:375
  14. Remnant gastric cancer (RGC) has been increasing for various reasons such as a longer life span, medical progress, and others. It generally has a poor prognosis, and its mechanism of occurrence is unknown. The...

    Authors: Yoshihiko Kakiuchi, Satoru Kikuchi, Shinji Kuroda, Shunsuke Kagawa and Toshiyoshi Fujiwara
    Citation: World Journal of Surgical Oncology 2022 20:374
  15. Recently, an increasing number of studies have been conducted on circular RNAs (circRNAs) that have demonstrated their different roles in a variety of biological processes. Moreover, a large number of circRNAs...

    Authors: Fan Zhang, Liying Li and Zhimin Fan
    Citation: World Journal of Surgical Oncology 2022 20:373
  16. Adjuvant chemoradiotherapy (CRT) has been shown to reduce the risk of recurrence for patients with risk factors after radical hysterectomy (RH). Early initiated CRT could result in superior oncological outcome...

    Authors: Qiying Zhang, Zi Liu, Yali Wang, Jing Zhang, Wen Li, Tao Wang, Juan Wang, Fan Shi and Jin Su
    Citation: World Journal of Surgical Oncology 2022 20:372
  17. Colorectal carcinoma with enteroblastic differentiation is a rare subtype of colorectal carcinomas expressing at least one characteristic immunohistochemical marker among α-fetoprotein, glypican-3, and spalt-like...

    Authors: Takako Kihara, Ryuichi Kuwahara, Kurando Kusunoki, Tomohiro Minagawa, Yuki Horio, Motoi Uchino, Hiroki Ikeuchi and Seiichi Hirota
    Citation: World Journal of Surgical Oncology 2022 20:371
  18. The role of lung surgery in initially unresectable non-small cell lung cancer (NSCLC) after tyrosine kinase inhibitor (TKI) treatment remains unclear. We aimed to assess the survival benefits of patients who u...

    Authors: Nguk Chai Diong, Chia-Chuan Liu, Chih-Shiun Shih, Mau-Ching Wu, Chun-Jen Huang and Chen-Fang Hung
    Citation: World Journal of Surgical Oncology 2022 20:370
  19. To assess the impact of malignant cystic renal masses (CRM) rupture on oncologic outcomes.

    Authors: Peirong Xu, Sihong Zhang, Bohong Cao, Jiaqi Huang, Yaohui Li, Jiangting Cheng, Wenyao Lin, Jie Cheng, Weijie Chen, Yanjun Zhu, Shuai Jiang, Xiaoyi Hu, Jianming Guo and Hang Wang
    Citation: World Journal of Surgical Oncology 2022 20:369
  20. This study aimed to investigate FAM84B expression in glioma tissues and explore the role of FAM84B in promoting the proliferation of glioma cells and the mechanism of regulating the cell cycle pathways.

    Authors: Deshuai Ren, Xiaoyu Zhuang, Yanxin Lv, Yun Zhang, Jiazhi Xu, Fengquan Gao, Dagang Chen and Yu Wang
    Citation: World Journal of Surgical Oncology 2022 20:368
  21. The debate surrounding systematic lymphadenectomy in the epithelial cancers of the ovary (EOC) was temporarily put to rest by the LION trial. However, there was a glaring disparity between the number of patien...

    Authors: Roli Purwar, Rakesh Ranjan, Kishan Soni, Manoj Pandey, Satyanshu K. Upadhyay, Esha Pai and Tarun Kumar
    Citation: World Journal of Surgical Oncology 2022 20:367
  22. The incidence of pancreatic neuroendocrine neoplasm (PNEN) has been increasing. Resection is typically indicated for PNEN, regardless of its size; however, the indications for its resection are controversial. ...

    Authors: Kodai Abe, Minoru Kitago, Eisuke Iwasaki, Hiroshi Yagi, Yuta Abe, Yasushi Hasegawa, Shutaro Hori, Masayuki Tanaka, Yutaka Nakano and Yuko Kitagawa
    Citation: World Journal of Surgical Oncology 2022 20:366
  23. Spontaneous rupture is a life-threatening complication of hepatocellular carcinoma (HCC). Recent trends in surgical treatments avoid emergency hepatectomy (EH) and favor emergency transarterial embolization (T...

    Authors: Wei Zhang, Zhangkan Huang and Xu Che
    Citation: World Journal of Surgical Oncology 2022 20:365
  24. Nonalcoholic fatty liver disease (NAFLD) as the leading chronic liver disease worldwide causes hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC). The aim of this study was to find potential aberra...

    Authors: Guizhi Zhang and Yinghui Hou
    Citation: World Journal of Surgical Oncology 2022 20:364
  25. In rectal cancer (RC) surgery, the complexity of total mesorectal excision (TME) in laparoscopic sphincter-preserving surgery (lap-SPS) for RC near the anus has been a critical issue. Recently, technical assis...

    Authors: Satoru Kagami, Kimihiko Funahashi, Takamaru Koda, Toshimitsu Ushigome, Tomoaki Kaneko, Takayuki Suzuki, Yasuyuki Miura, Yasuo Nagashima, Kimihiko Yoshida and Akiharu Kurihara
    Citation: World Journal of Surgical Oncology 2022 20:363
  26. Gastric cancer has a high incidence and mortality rate. Angiogenesis is necessary for tumor infiltration and metastasis and affects patient prognosis. YKL-39 has monocyte chemotactic activity and pro-angiogeni...

    Authors: Ling Xue, Wei Chu, Fangsheng Wan, Pingfan Wu, Xiaowen Zhao, Linna Ma, Yali She, Changtian Li and Yaling Li
    Citation: World Journal of Surgical Oncology 2022 20:362
  27. Many studies have reported the relationship between prognosis and Slug protein expression in breast cancer patients, but the results are discrepant. Therefore, there is a need for meta-analyses with high stati...

    Authors: Zhihao Zhang, Tian Fang and Yonggang Lv
    Citation: World Journal of Surgical Oncology 2022 20:361
  28. Pheochromocytomas (PCC) are rare and functional neuroendocrine tumors developing from adrenal chromaffin cells. Predicting malignant behavior especially in the absence of metastasis can be quite challenging ev...

    Authors: Sarah S. Tang, James W. K. Lee, Sujith Wijerethne, Shridhar Ganpathi Iyer, Susan Hue, Nga Min En and Rajeev Parameswaran
    Citation: World Journal of Surgical Oncology 2022 20:360
  29. The molecular mechanism of laryngeal squamous cell carcinoma (LSCC) is not completely clear, which leads to poor prognosis and treatment difficulties for LSCC patients. To date, no study has reported the exact...

    Authors: Fang-Cheng Jiang, Jia-Yuan Luo, Yi-Wu Dang, Hui-Ping Lu, Dong-Ming Li, Zhi-Guang Huang, Yu-Lu Tang, Ye-Ying Fang, Yu-Xing Tang, Ya-Si Su, Wen-Bin Dai, Shang-Ling Pan, Zhen-Bo Feng, Gang Chen and Juan He
    Citation: World Journal of Surgical Oncology 2022 20:359
  30. To report long-term oncological outcomes and organ preservation rate with a chemoradiotherapy-consolidation chemotherapy (CRT-CNCT) treatment for locally advanced rectal cancer (LARC).

    Authors: Oktar Asoglu, Alisina Bulut, Vusal Aliyev, Guglielmo Niccolò Piozzi, Koray Guven, Barıs Bakır and Suha Goksel
    Citation: World Journal of Surgical Oncology 2022 20:358
  31. To evaluate the feasibility and accuracy of near-infrared fluorescence imaging technology for assessing margins during breast-conserving surgery for breast cancer.

    Authors: Yabing Wang, Wei Jiao, Zhaocai Yin, Wanjun Zhao, Kai Zhao, Yong Zhou, Rui Fang, Bingbin Dong, Bin Chen and Zheng Wang
    Citation: World Journal of Surgical Oncology 2022 20:357
  32. Gastric neuroendocrine neoplasm (g-NEN) is a rare but heterogeneous neoplasm, with an increasing incidence yearly. Conventional prognostic markers of g-NEN remain limited which could only be detected after sur...

    Authors: Wenquan Liang, Xinxin Xu, Yuhua Liu, Jianxin Cui, Yunhe Gao, Chuang Wang, Ziwei Zhuang, Kecheng Zhang, Hongqing Xi, Aizhen Cai, Bo Wei and Lin Chen
    Citation: World Journal of Surgical Oncology 2022 20:356
  33. Laparoscopic radical distal gastrectomy (LDG) has been more frequently performed for locally advanced distal gastric cancer (AGC) than open distal gastrectomy (ODG). However, the benefits of LDG for elderly AG...

    Authors: Hung-Hsuan Yen, Chi-Chuan Yeh and I-Rue Lai
    Citation: World Journal of Surgical Oncology 2022 20:355
  34. This meta-analysis aims to explore the association between angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism and susceptibility to prostate cancer (PCa).

    Authors: Jianhui Du, Jianhua Lan, Hai Yang, Qiao Ying, Guohua Huang, Jian Mou, Jia Long, Zhenghua Qiao and Qiyi Hu
    Citation: World Journal of Surgical Oncology 2022 20:354
  35. Primary squamous cell carcinoma of thyroid gland (PSCCT) is a highly aggressive malignant tumor associated with a poor prognosis. Due to the rare case, there is a knowledge gap on the features of PSCCT. There ...

    Authors: Wanyun Yan, Huiying Chen, Jiangmiao Li, Ruifa Zhou and Jiping Su
    Citation: World Journal of Surgical Oncology 2022 20:352
  36. It has been previously reported that CD155 is often over-expressed in a variety of cancer types. In fact, it is known to be involved in cancer development, and its role in cancer has been widely established. H...

    Authors: Dan Zhang, Jingting Liu, Mengxia Zheng, Chunyan Meng and Jianhua Liao
    Citation: World Journal of Surgical Oncology 2022 20:351
  37. Malignant peritoneal mesothelioma (MPM) is a rare malignant tumor with a high mortality rate and extremely poor prognosis. In-depth pathological analysis is essential to assess tumor biological behaviors and e...

    Authors: He-liang Wu, Zhi-ran Yang, Yan-dong Su, Ru Ma, Xue-mei Du, Ying Gao and Yan Li
    Citation: World Journal of Surgical Oncology 2022 20:350
  38. High expression of immune checkpoint receptors (ICRs) in the tumor microenvironment regulates the anti-tumor response. In this study, the differential expressions of ICRs on tumor-infiltrating lymphocytes (TIL...

    Authors: Baran Mollavelioglu, Esin Cetin Aktas, Neslihan Cabioglu, Aykhan Abbasov, Semen Onder, Selman Emiroglu, Mustafa Tükenmez, Mahmut Muslumanoglu, Abdullah Igci, Gunnur Deniz and Vahit Ozmen
    Citation: World Journal of Surgical Oncology 2022 20:349
  39. This study focused on evaluating whether high-intensity interval training (HIIT) had an effect on aerobic capacity and fatigue among patients with prostate cancer (PCa) and exploring its effect on the immune s...

    Authors: Ming Chang, Junguo Wang, Hairul A. Hashim, Shihao Xie and Adam A. Malik
    Citation: World Journal of Surgical Oncology 2022 20:348
  40. Gelsolin-like capping actin protein (CapG) modulates actin dynamics and actin-based motility with a debatable role in tumorigenic progression. The motility-associated functions and potential molecular mechanis...

    Authors: Ying Fu, Xiuzhi Zhang, Xujun Liang, Yongheng Chen, Zhuchu Chen and Zhefeng Xiao
    Citation: World Journal of Surgical Oncology 2022 20:347
  41. The prognosis of hepatocellular carcinoma (HCC) varies considerably among patients with the same disease stage and characteristics, and only about two thirds show high levels of α-fetoprotein (AFP), a common p...

    Authors: Jie Zhang, Shang Dong Qin, Yan Li, Fei Lu, Wen Feng Gong, Jian Hong Zhong, Liang Ma, Jing Fei Zhao, Guo Hua Zhan, Peng Zhan Li, Bin Song and Bang De Xiang
    Citation: World Journal of Surgical Oncology 2022 20:346
  42. Robotic surgery has been widely used in the radical treatment of colonic cancer. However, it is unclear what advantages the robotic approach offers over other approaches in left colectomy. This study aims to e...

    Authors: Zhixiang Huang, Taiyuan Li, Genghua Zhang, Zhen Zhou, Haoran Shi, Cheng Tang, Lingling Yang and Xiong Lei
    Citation: World Journal of Surgical Oncology 2022 20:345
  43. Quality standards in postoperative outcomes have not yet been defined for gastric cancer surgery. Also, the effect of centralization of gastric cancer surgery on the improvement of postoperative outcomes conti...

    Authors: Francisco-Javier Lacueva, Javier Escrig-Sos, Roberto Marti-Obiol, Carmen Zaragoza, Fernando Mingol, Miguel Oviedo, Nuria Peris, Joaquin Civera and Amparo Roig
    Citation: World Journal of Surgical Oncology 2022 20:344
  44. Cervical carcinoma (CC) has been associated with high morbidity, poor prognosis, and high intratumor heterogeneity. Necroptosis is the significant cellular signal pathway in tumors which may overcome tumor cel...

    Authors: Kai Sun, Cheng Huang, Jing-zhang Li and Zhan-xiong Luo
    Citation: World Journal of Surgical Oncology 2022 20:342
  45. Pancreatic metastasis from colorectal cancer is extremely rare. Here, we report a case of colorectal cancer with lung and pancreatic metastasis and analyze the histopathology, immunohistochemistry, and next-ge...

    Authors: Xiang Wu, Shuping Zhou, Xinhua Zhou, Xiao Xu, Luoluo Wang, Yi Ruan, Jun Lu, Haili Li, Hongfeng Xu, Xinyi Ma and Hong Li
    Citation: World Journal of Surgical Oncology 2022 20:341
  46. The importance of stroma for tumor progression is recognized for many cancer types. In this study, we aim to evaluate the expression of types I (Col1) and IV (Col4) collagens, alpha-smooth muscle actin (a-SMA)...

    Authors: Haytham Bayadsi, George Barghout, Moa Gustafsson, Malin Sund and Joakim Hennings
    Citation: World Journal of Surgical Oncology 2022 20:340
  47. Laryngeal cancer is a common malignancy in otorhinolaryngological head and neck surgery, accounting for approximately one-third of all head and neck malignancies. Terahertz time-domain spectroscopy (THz-TDS) h...

    Authors: Jing Ke, Lifeng Jia, Yaqin Hu, Xu Jiang, Hailan Mo, Xiang An and Wei Yuan
    Citation: World Journal of Surgical Oncology 2022 20:339

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