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  1. Neuroendocrine carcinoma is an aggressive neoplasm that mainly affects elderly Caucasians and typically arises in sun-exposed areas of the skin. The disease is rather rare and only a relatively few cases prese...

    Authors: Van Boghossian, Ira D Owen, Balakrishna Nuli and Philip Q Xiao

    Citation: World Journal of Surgical Oncology 2007 5:117

    Content type: Case report

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  2. The most common tumours of the adrenal gland are adenoma, pheochromocytoma, adrenocortical carcinoma, and metastases. Although the imaging features of these tumours are established, the imaging characteristics...

    Authors: Izhar N Bagwan, Gary Cook, Satvinder Mudan and Andrew Wotherspoon

    Citation: World Journal of Surgical Oncology 2007 5:116

    Content type: Technical innovations

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  3. Presacral masses are unusual growths that have a limited differential diagnosis, typically not including neuroendocrine tumors (NETs). Classically, NETs are well-differentiated gastroenteropancreatic tumors of...

    Authors: Tad Kim, Stephen R Grobmyer, Chen Liu and Steven N Hochwald

    Citation: World Journal of Surgical Oncology 2007 5:115

    Content type: Case report

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  4. Different molecular therapies like the EGFR-inhibiting antibody cetuximab have come into clinical practice. Cetuximab is EMEA-approved for metastatic colorectal cancer and advanced squamous-cell head and neck ...

    Authors: Michael Knauer, Anton Haid, Karlheinz Ammann, Alois Lang, Felix Offner, Martina Türtscher, Peter Cerkl and Etienne Wenzl

    Citation: World Journal of Surgical Oncology 2007 5:114

    Content type: Case report

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  5. Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited disease. It is relatively recent that type 2C was identified as a separate group solely presenting with pheochromocytomas. As an illustration,...

    Authors: Jennifer M J Schreinemakers, Bernard A Zonnenberg, Jo W M Höppener, Frederik J Hes, Inne H M Borel Rinkes and Cornelis J M Lips

    Citation: World Journal of Surgical Oncology 2007 5:112

    Content type: Case report

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  6. Simple or unicameral bone cysts are common benign fluid-filled lesions usually located at the long bones of children before skeletal maturity.

    Authors: Anastasios D Kanellopoulos, Andreas F Mavrogenis, Panayiotis J Papagelopoulos and Panayotis N Soucacos

    Citation: World Journal of Surgical Oncology 2007 5:111

    Content type: Technical innovations

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  7. Caveolin-1 is thought to have an important impact on both signal transduction and mediation of intracellular processes. Furthermore, it has been suggested that Caveolin-1 may contribute to certain steps of car...

    Authors: Cornelia Liedtke, Christian Kersting, Horst Bürger, Ludwig Kiesel and Pia Wülfing

    Citation: World Journal of Surgical Oncology 2007 5:110

    Content type: Research

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  8. Leiomyosarcomas typically originate within smooth muscle cells. Leiomyosarcomas arising from the adrenal vein are rare malignancies associated with delayed diagnosis and poor prognosis. The most common vascula...

    Authors: Tracy S Wang, Idris Tolgay Ocal, Ronald R Salem, John Elefteriades and Julie A Sosa

    Citation: World Journal of Surgical Oncology 2007 5:109

    Content type: Technical innovations

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  9. The cost effective treatment of cancer in developing countries remains challenging. In the elderly with possible limited life expectancy, the health expenditure associated with standard treatment regimes shoul...

    Authors: Lukas J Wasserman, Justus P Apffelstaedt and Jacobus de V Odendaal

    Citation: World Journal of Surgical Oncology 2007 5:108

    Content type: Research

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  10. Inflammatory pseudotumor of the kidney or inflammatory myofibroblastic tumor (IMT) is composed of spindle cells admixed with variable amount of proliferating myofibroblasts, fibroblasts, extracellular collagen...

    Authors: David R Selvan, Joe Philip, Ramaswamy Manikandan, Timothy R Helliwell, Gabriel H R Lamb and Anthony D Desmond

    Citation: World Journal of Surgical Oncology 2007 5:106

    Content type: Case report

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  11. As a result of improvements in diagnostic accuracy, the primary source of the tumour is identified in more than 99% of cases presenting with a malignancy. Whilst the axial skeleton is a common site of metastas...

    Authors: Elizabeth Ball, Gareth Morris-Stiff, Mari Coxon and Michael H Lewis

    Citation: World Journal of Surgical Oncology 2007 5:105

    Content type: Case report

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  12. Seroma formation following modified radical mastectomy with axillary lymph node dissection for breast cancer is a most common wound complication. In our experience seroma occurs in approximately 50% of patient...

    Authors: Marek Stanczyk, Bartlomiej Grala, Tomasz Zwierowicz and Marek Maruszynski

    Citation: World Journal of Surgical Oncology 2007 5:104

    Content type: Case report

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  13. Cystic neoplasms of the pancreas comprise 10%–15% of pancreatic cystic lesions, with the serous cystadenoms being the commonest. The association of exocrine and endocrine tumours of the pancreas unrelated to V...

    Authors: Ahmed Alzaraa, Valeri Udom, Husam Mousa, Abdulhalem Alzein, Abduljalil Benhamida and Neha Dalal

    Citation: World Journal of Surgical Oncology 2007 5:103

    Content type: Case report

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  14. Women that carry germ-line mutations for BRCA1 or BRCA2 genes are at an increased risk of developing breast, ovarian and peritoneal cancer. Primary peritoneal carcinoma is a rare tumour histologically identical t...

    Authors: Manish Chand, Patrick J Moore, Andrew D Clarke, Guy F Nash and Tamas Hickisk

    Citation: World Journal of Surgical Oncology 2007 5:102

    Content type: Case report

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  15. Breast cancer is usually associated with metastases to lungs, bones and liver. Breast carcinoma metastasizing to the gallbladder is very rare.

    Authors: Flora Zagouri, Theodoros N Sergentanis, Dimitra Koulocheri, Afroditi Nonni, Aggeliki Bousiotou, Philip Domeyer, Nikolaos V Michalopoulos, Dimitrios Dardamanis, Manousos M Konstadoulakis and George C Zografos

    Citation: World Journal of Surgical Oncology 2007 5:101

    Content type: Case report

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  16. Eccrine carcinoma is a quite rare malignant tumor that typically arises from a normal sweat gland and that features a rather high recurrence rate subsequent to simple excision. Given its rather poor response t...

    Authors: Tsz-Ho Leung, Henry Hsin-Chung Lee and Shih-Chang Chang

    Citation: World Journal of Surgical Oncology 2007 5:100

    Content type: Case report

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  17. Doppler ultrasonography (US) is increasingly being utilized as an imaging modality in breast cancer. It is used to study the vascular characteristics of the tumor. Neoadjuvant chemotherapy is the standard moda...

    Authors: Anand Kumar, Seema Singh, Satyajit Pradhan, Ram C Shukla, Mumtaz A Ansari, Tej B Singh, Rohit Shyam and Saroj Gupta

    Citation: World Journal of Surgical Oncology 2007 5:99

    Content type: Technical innovations

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  18. Although intraductal papillary mucinous neoplasm (IPMN) of the pancreas is acceptable as a distinct disease entity, the concept of mucin-secreting biliary tumors has not been fully established.

    Authors: Yo-ichi Yamashita, Kengo Fukuzawa, Akinobu Taketomi, Shinichi Aishima, Tomoharu Yoshizumi, Hideaki Uchiyama, Eiji Tsujita, Norifumi Harimoto, Noboru Harada, Kenzo Wakasugi and Yoshihiko Maehara

    Citation: World Journal of Surgical Oncology 2007 5:98

    Content type: Case report

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  19. Gastrointestinal stromal tumors (GIST) represent the most common mesenchymal tumors of the digestive tract. Over the last ten years the management of GISTs has dramatically altered but their coexistence with o...

    Authors: Papalambros Efstathios, Petrou Athanasios, Ioannis Papaconstantinou, Papalambros Alexandros, Sigala Frangisca, Georgopoulos Sotirios, Felekouras Evangelos and Giannopoulos Athanasios

    Citation: World Journal of Surgical Oncology 2007 5:96

    Content type: Case report

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  20. The choice of operation for tumours at or around the gastro-oesophageal junction remains controversial with little evidence to support one technique over another. This study examines the prevalence of margin i...

    Authors: Stuart A Suttie, Alan GK Li, Martha Quinn and Kenneth GM Park

    Citation: World Journal of Surgical Oncology 2007 5:95

    Content type: Research

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  21. Anastomotic recurrence is often experienced at colocolic or colorectal anastomoses. Tumor cell implantation has been reported as the mechanism of anastomotic recurrence. However, anastomotic recurrence occurri...

    Authors: Kimihiko Funahashi, Junichi Koike, Naoyasu Saito, Hiroyuki Shiokawa, Kentaro Shirasaka and Tatsuo Teramoto

    Citation: World Journal of Surgical Oncology 2007 5:91

    Content type: Case report

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  22. Colorectal cancer is the third commonest cause of cancer death in UK. It commonly metastasises to the liver but rarely to small bones.

    Authors: Nishith NB Patel, Parin R Shah, Eliie Wilson and Puthcode N Haray

    Citation: World Journal of Surgical Oncology 2007 5:90

    Content type: Case report

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  23. Malignant gliomas recur even after extensive surgery and chemo-radiotherapy. Although a relatively novel chemotherapeutic agent, temozolomide (TMZ), has demonstrated promising activity against recurrent glioma...

    Authors: Takamitsu Fujimaki, Hisato Ishii, Akira Matsuno, Hajime Arai and Tadayoshi Nakagomi

    Citation: World Journal of Surgical Oncology 2007 5:89

    Content type: Case report

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  24. The skeletal muscle is an unusual site for metastasis from renal cell carcinoma (RCC). Metastatic RCC must be differentiated from benign primary soft-tissue tumors because aggressive surgical resection is nece...

    Authors: Akio Sakamoto, Tatsuya Yoshida, Suguru Matsuura, Kazuhiro Tanaka, Shuichi Matsuda, Yoshinao Oda, Yoshifumi Hori, Akira Yokomizo and Yukihide Iwamoto

    Citation: World Journal of Surgical Oncology 2007 5:88

    Content type: Case report

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  25. Extra-adrenal, intra-abdominal paraganglioma constitutes a rare neoplasm and, moreover, its location in the greater omentum is extremely infrequent.

    Authors: Fotios Archontovasilis, Haridimos Markogiannakis, Christina Dikoglou, Panagiotis Drimousis, Konstantinos G Toutouzas, Dimitrios Theodorou and Stilianos Katsaragakis

    Citation: World Journal of Surgical Oncology 2007 5:87

    Content type: Case report

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  26. Solitary involvement of the sphenoid sinus has rarely been reported in non-Hodgkin's lymphoma. Isolated oculomotor nerve palsy is uncommon as an initial presentation of malignant tumors of the sphenoid sinus.

    Authors: Young Mok Park, Jun Hyung Cho, Jae Yong Cho, Ji Soon Huh and Jung Yong Ahn

    Citation: World Journal of Surgical Oncology 2007 5:86

    Content type: Case report

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  27. Dermoid cyst of the pancreas is a benign, well-differentiated, extremely rare germ cell neoplasm. Published data indicate that differential diagnosis of cystic lesions of the pancreas is challenging and althou...

    Authors: Gianfranco Tucci, Marco Gallinella Muzi, Casimiro Nigro, Federica Cadeddu, Dalia Amabile, Francesca Servadei and Attilio M Farinon

    Citation: World Journal of Surgical Oncology 2007 5:85

    Content type: Review

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  28. Previous studies suggest that chemokines (chemotactic cytokines) promote and regulate neoplastic progression including metastasis and angiogenesis. The chemokine eotaxin-1 is a powerful eosinophil attractant b...

    Authors: Dick Wågsäter, Sture Löfgren, Anders Hugander, Olaf Dienus and Jan Dimberg

    Citation: World Journal of Surgical Oncology 2007 5:84

    Content type: Research

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  29. Minimally invasive breast biopsy technology is now considered a standard of care for the diagnostic evaluation of suspicious breast lesions. The aim of the current study was to present a comprehensive evaluati...

    Authors: Stephen P Povoski and Rafael E Jimenez

    Citation: World Journal of Surgical Oncology 2007 5:83

    Content type: Research

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  30. The relationship between radiation exposure for treatment of cancer and occurrence of a second primary cancer at the irradiated site is well known. This phenomenon is however rare in prostate.

    Authors: Saleh M Abbas and Andrew G Hill

    Citation: World Journal of Surgical Oncology 2007 5:82

    Content type: Case report

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  31. The purpose of this study was to combine intraoperative gamma probe (GP) detection with preoperative fluorine 18-fluoro-2-deoxy-glucose positron emission tomography (18F FDG-PET) imaging in order to improve detec...

    Authors: Ismet Sarikaya, Stephen P Povoski, Osama H Al-Saif, Ergun Kocak, Mark Bloomston, Steven Marsh, Zongjian Cao, Douglas A Murrey, Jun Zhang, Nathan C Hall, Michael V Knopp and Edward W Martin Jr

    Citation: World Journal of Surgical Oncology 2007 5:80

    Content type: Research

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  32. Alpha-fetoprotein (AFP)-producing gastric cancer is known to frequently cause multiple liver metastases and to have an extremely poor prognosis.

    Authors: Hiromitsu Takeyama, Hirozumi Sawai, Takehiro Wakasugi, Hiroki Takahashi, Yoichi Matsuo, Nobuo Ochi, Akira Yasuda, Mikinori Sato, Yuji Okada, Hitoshi Funahashi, Yoshimi Akamo and Tadao Manabe

    Citation: World Journal of Surgical Oncology 2007 5:79

    Content type: Case report

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  33. Gastrointestinal stromal tumours (GIST) are rare tumours, now more frequently identified with the new imaging modalities like computerised tomography (CT) and magnetic resonance imaging (MRI). We report a rare...

    Authors: Solomon KP John, Sanjoy Basu, Richard J Lawrance and Nick Davies

    Citation: World Journal of Surgical Oncology 2007 5:78

    Content type: Case report

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  34. Extremely rare cases of paraneoplastic syndromes or ectopic production of proteins associated with liposarcoma are reported in literature. Production of Granulocyte-Colony Stimulating Factor, alpha-fetoprotein...

    Authors: Francesco Tartaglia, Sara Blasi, Monica Sgueglia, Paolo Polichetti, Luciana Tromba and Alberto Berni

    Citation: World Journal of Surgical Oncology 2007 5:76

    Content type: Case report

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  35. The stomach is an infrequent site of breast cancer metastasis. It may prove very difficult to distinguish a breast cancer metastasis to the stomach from a primary gastric cancer on the basis of clinical, endos...

    Authors: Gregory E Jones, Dirk C Strauss, Matthew J Forshaw, Harriet Deere, Ula Mahedeva and Robert C Mason

    Citation: World Journal of Surgical Oncology 2007 5:75

    Content type: Review

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  36. Metastases to the breast occur rarely, but may be increasing in incidence as patients live longer with malignant diseases. The aim of this study is to characterize metastatic disease to the breast and to descr...

    Authors: Aislinn Vaughan, Jill R Dietz, Jeffrey F Moley, Mary K DeBenedetti, Rebecca L Aft, William E Gillanders, Timothy J Eberlein, Jon Ritter and Julie A Margenthaler

    Citation: World Journal of Surgical Oncology 2007 5:74

    Content type: Research

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  37. This study evaluates the surgical morbidity and long-term outcome of colorectal cancer surgery in an unselected group of patients treated over the period 1994–2003.

    Authors: Bruno Andreoni, Antonio Chiappa, Emilio Bertani, Massimo Bellomi, Roberto Orecchia, MariaGiulia Zampino, Nicola Fazio, Marco Venturino, Franco Orsi, Angelica Sonzogni, Ugo Pace and Lorenzo Monfardini

    Citation: World Journal of Surgical Oncology 2007 5:73

    Content type: Research

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  38. Primary leptomeningeal astrocytomas are rare intracranial tumors. These tumors are believed to originate from cellular nests which migrate by means of aberration, ultimately settling in the leptomeningeal stru...

    Authors: Antonio De Tommasi, Giuseppe Occhiogrosso, Claudio De Tommasi, Sabino Luzzi, Antonella Cimmino and Pasqualino Ciappetta

    Citation: World Journal of Surgical Oncology 2007 5:72

    Content type: Case report

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  39. Dysgerminoma is the most common malignant germ cell tumor of the ovary. This malignancy can be associated with pure gonadal dysgenesis or Swyer syndrome, mixed gonadal dysgenesis and partial gonadal dysgenesis.

    Authors: Nadereh Behtash and Mojgan Karimi Zarchi

    Citation: World Journal of Surgical Oncology 2007 5:71

    Content type: Review

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  40. The efficacy of operative resection of liver metastasis from colorectal cancer has been established. However, a treatment for liver metastasis from gastric cancer has not yet been established. In this study, w...

    Authors: Hitoshi Ojima, Sayaka Ootake, Takehiko Yokobori, Yasushi Mochida, Yasuo Hosouchi, Yasuji Nishida and Hiroyuki Kuwano

    Citation: World Journal of Surgical Oncology 2007 5:70

    Content type: Research

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  41. Cavernous lymphangioma is a rare lesion in the breast of adults. Only a few cases have been documented in literature.

    Authors: Gabriel O Ogun, O Oyetunde and EffiongE Akang

    Citation: World Journal of Surgical Oncology 2007 5:69

    Content type: Case report

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