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  1. The role of hypoxia-inducible factor-1α (HIF-1α) in primary colorectal cancer (CRC) and colorectal liver metastasis (CRLM) has remained unclear. The aim of this study was to investigate HIF-1α expression and i...

    Authors: Yuma Wada, Yuji Morine, Satoru Imura, Tetsuya Ikemoto, Yu Saito, Chie Takasu, Shinichiro Yamada and Mitsuo Shimada

    Citation: World Journal of Surgical Oncology 2020 18:241

    Content type: Research

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  2. Thyroid cancer (TC) is the most common endocrine malignancy; basigin (also known as BSG) plays a crucial role in tumor cell invasion, metastasis, and angiogenesis. This study was designed to identify the chang...

    Authors: Wan-Ping Guo, Deng Tang, Yu-Yan Pang, Xiao-Jiao Li, Gang Chen, Zhi-Guang Huang, Xiao-Zhun Tang, Qin-Qiao Lai, Jin-Yan Gan, Xiao-Li Huang, Xiao-Fan Liu, Zhi-Xiao Wei and Wei Ma

    Citation: World Journal of Surgical Oncology 2020 18:240

    Content type: Research

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  3. This study was designed to evaluate the effect of preoperative jaundice on long-term prognosis of gallbladder carcinoma (GBC) after radical resection (R0).

    Authors: Xin-wei Yang, Jun-yi Chen, Zhi-jian Wen, Yu-long Li, Fei-yu Wang, Liang Li, Jue Yang, Ping-hua Yang, Bao-hua Zhang and Feng Shen

    Citation: World Journal of Surgical Oncology 2020 18:239

    Content type: Research

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  4. Pancreatic cancer composed of acinar cell carcinoma (ACC) and ductal adenocarcinoma (DAC) is rare, and the clinicopathological characteristics of ACC with DAC have yet to be elucidated. Herein, we report a cas...

    Authors: Toshihisa Kimura, Shinsuke Tabata, Tamotsu Togawa, Hidetoshi Onchi, Atsushi Iida, Yasunori Sato and Takanori Goi

    Citation: World Journal of Surgical Oncology 2020 18:238

    Content type: Case report

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  5. Resection of colorectal liver metastases (CLM) has been established as the standard of care. This study aims to compare the change in clinicopathological characteristics of patients who underwent curative rese...

    Authors: Lionel Chen, Nicholas L. Syn, Brian K. P. Goh, Peng Chung Cheow, Prema Raj, Yexin Koh, Alexander Chung, Ser Yee Lee, London Lucien Ooi, Chung Yip Chan and Jin Yao Teo

    Citation: World Journal of Surgical Oncology 2020 18:237

    Content type: Research

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  7. Several randomized controlled trials (RCTs) have compared the treatment of acute lung injury (ALI) with omega-3 fatty, yet the results remained inconsistent. Therefore, we attempted this meta-analysis to analy...

    Authors: Zhongjie Huang, Jianming Zheng, Wencheng Huang, Meihao Yan, Liyue Hong, Yuancheng Hong, Runnv Jin, Xincheng Huang, Hongtao Fan, Huiling Chen, Heping Yang, Weiping Su and Xiaoping Huang

    Citation: World Journal of Surgical Oncology 2020 18:235

    Content type: Research

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  8. Pelvic exenteration (PE) may be associated with prolonged overall survival (OS) in selected patients with advanced or recurrent cervical cancer. However, the factors related to improved survival following PE a...

    Authors: Agnieszka Lewandowska, Sebastian Szubert, Krzysztof Koper, Agnieszka Koper, Grzegorz Cwynar and Lukasz Wicherek

    Citation: World Journal of Surgical Oncology 2020 18:234

    Content type: Research

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  9. The issue of whether or not splenic hilum lymph nodes (SHLN) should be excised in radical gastrectomy with D2 lymph node dissection remains controversial. In this study, we identified the clinicopathological f...

    Authors: Jun Du, Yangchao Shen, Wenwu Yan and Jinguo Wang

    Citation: World Journal of Surgical Oncology 2020 18:233

    Content type: Research

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  10. Neoadjuvant therapy can shrink tumors, increase anus preservation rate, and protect anal function. Radical surgery need cut off the diseased bowel, clean up the lymph nodes, and then restore bowel function. It...

    Authors: Guo-hua Zhao, Li Deng, Dong-man Ye, Wen-hui Wang, Yan Yan and Tao Yu

    Citation: World Journal of Surgical Oncology 2020 18:232

    Content type: Research

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  11. There have been very few reports of patients with early gastric cancer (EGC) and colorectal cancer combined with gastric gastrointestinal stromal tumors (GISTs).

    Authors: Sung Chul Lee, Kwangwoo Nam, Dajeong Nam, Min A Kwon and Dong-Wook Kim

    Citation: World Journal of Surgical Oncology 2020 18:231

    Content type: Case report

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    The Correction to this article has been published in World Journal of Surgical Oncology 2020 18:256

  12. The clinical significance of pre-sarcopenia in colorectal cancer obstruction has not yet been described. The present study aimed to determine the short- and long-term oncologic impacts of pre-sarcopenia in obs...

    Authors: Chul Seung Lee, Daeyoun David Won, Soon Nam Oh, Yoon Suk Lee, In Kyu Lee, In-Ho Kim, Moon Hyung Choi and Seong Taek Oh

    Citation: World Journal of Surgical Oncology 2020 18:230

    Content type: Research

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  13. Synchronous metastatic para-aortic lymph node (mPALN) dissectionin colorectal cancer has relatively good oncological outcomes, though many patients develop recurrence. Universal prognostic factor remain unclea...

    Authors: Hajime Ushigome, Masayoshi Yasui, Masayuki Ohue, Naoaki Haraguchi, Junichi Nishimura, Keijirou Sugimura, Kazuyoshi Yamamoto, Hiroshi Wada, Hidenori Takahashi, Takeshi Omori, Hiroshi Miyata and Shuji Takiguchi

    Citation: World Journal of Surgical Oncology 2020 18:229

    Content type: Research

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  14. Chordoma of the spine is a low-grade malignant tumor with vague and indolent symptoms; thus, large tumor mass is encountered at the time of diagnosis in almost cases and makes it difficult for en-bloc free-mar...

    Authors: Pongsthorn Chanplakorn, Thamrong Lertudomphonwanit, Wittawat Homcharoen, Prakrit Suwanpramote and Wichien Laohacharoensombat

    Citation: World Journal of Surgical Oncology 2020 18:228

    Content type: Research

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  15. Myxoid liposarcoma is well known to have an unusual proclivity for extrapulmonary metastasis. However, cardiac metastasis of myxoid liposarcoma is very rare, even in patients with advanced disease.

    Authors: Kunihiro Ikuta, Tomohisa Sakai, Hiroshi Koike, Tohru Okada, Shiro Imagama and Yoshihiro Nishida

    Citation: World Journal of Surgical Oncology 2020 18:227

    Content type: Case report

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  16. Current researches have revealed that delta-like protein 3 (DLL3) may be related with prognosis in patients with small cell lung cancer (SCLC). However, this finding remains controversial in small cell lung ca...

    Authors: Benchao Chen, Heng Li, Chao Liu, Shuting Wang, Feiyue Zhang, Li Zhang, Mingjie Li and Gaofeng Li

    Citation: World Journal of Surgical Oncology 2020 18:226

    Content type: Research

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  17. The cell proliferative markers are very important in breast cancer. Since SPAG5 and NuMA proteins play a significant role in the mitosis regulatory network and cell division, we aimed to study their mRNA level...

    Authors: Zeinab Mohamadalizadeh-Hanjani, Shirin Shahbazi and Loabat Geranpayeh

    Citation: World Journal of Surgical Oncology 2020 18:225

    Content type: Research

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  18. It is well established that retrieved lymph node (RLN) counts were positively correlated with better overall survival in gastric cancer (GC). But little is known about the relationship between RLN count and sh...

    Authors: Feng Sun, Song Liu, Peng Song, Chen Zhang, Zhijian Liu, Wenxian Guan and Meng Wang

    Citation: World Journal of Surgical Oncology 2020 18:224

    Content type: Research

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  19. Three-dimensional (3D) computed tomography (CT) reconstruction technology has gained attention owing to its potential in locating ground glass nodules in the lung. The 3D printing technology additionally allow...

    Authors: Yangming Chen, Jiguang Zhang, Qianshun Chen, Tian Li, Kai Chen, Qinghua Yu and Xing Lin

    Citation: World Journal of Surgical Oncology 2020 18:223

    Content type: Research

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  20. Although RNA-binding proteins play an essential role in a variety of different tumours, there are still limited efforts made to systematically analyse the role of RNA-binding proteins (RBPs) in the survival of...

    Authors: Xuehui Fan, Lili Liu, Yue Shi, Fanghan Guo, Haining Wang, Xiuli Zhao, Di Zhong and Guozhong Li

    Citation: World Journal of Surgical Oncology 2020 18:222

    Content type: Research

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  21. Sarcopenia is a prognostic factor in various cancers. However, the impact of sarcopenia in patients with recurrent pancreatic cancer remains unclear. This study evaluated the prognostic significance of sarcope...

    Authors: Teruhisa Sakamoto, Takuki Yagyu, Ei Uchinaka, Kozo Miyatani, Takehiko Hanaki, Kyoichi Kihara, Tomoyuki Matsunaga, Manabu Yamamoto, Naruo Tokuyasu, Soichiro Honjo and Yoshiyuki Fujiwara

    Citation: World Journal of Surgical Oncology 2020 18:221

    Content type: Research

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  23. Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver, and its morbidity and mortality have been increasing in recent years. The early diagnosis and prompt treatment of small HCC are c...

    Authors: Xue-Qin Li, Xing Wang, Da-Wei Zhao, Jun Sun, Jiao-Jiao Liu, Dong-Dong Lin, Guang Yang, Hui Liu, Zhen-Ying Xia, Cui-Yu Jia and Hong-Jun Li

    Citation: World Journal of Surgical Oncology 2020 18:219

    Content type: Review

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  24. Adenocarcinoma of the pancreatic body and tail is associated with a dismal prognosis. As patients frequently present themselves with locally advanced tumors, extended surgery including multivisceral resection ...

    Authors: Oliver Beetz, Akin Sarisin, Alexander Kaltenborn, Jürgen Klempnauer, Michael Winkler and Gerrit Grannas

    Citation: World Journal of Surgical Oncology 2020 18:218

    Content type: Research

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  26. Transurethral resection of the bladder tumour (TUR) is associated with a risk of bladder perforation. The underlying mechanisms and risk factors are not fully understood. The aim of this study was to determine...

    Authors: Sławomir Poletajew, Tomasz Ilczuk, Wojciech Krajewski, Grzegorz Niemczyk, Agata Cyran, Łukasz Białek, Piotr Radziszewski, Barbara Górnicka and Piotr Kryst

    Citation: World Journal of Surgical Oncology 2020 18:216

    Content type: Research

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  27. Natural orifice specimen extraction surgery is a novel technique of minimally invasive surgery. The purpose of this study was to compare the safety of laparoscopic anterior resection with natural orifice speci...

    Authors: Jun He, Hai-Bo Yao, Chang-Jian Wang, Qin-Yan Yang, Jian-Ming Qiu, Jin-Ming Chen, Zhong Shen and Guan-Gen Yang

    Citation: World Journal of Surgical Oncology 2020 18:215

    Content type: Research

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  28. Recently, a novel surgical procedure, named as laparoscopic proximal gastrectomy (LPG) with double-tract reconstruction (DTR), has been reported to provide surgical benefits in the treatment of proximal early ...

    Authors: Yixin Xu, Jie Gao, Yibo Wang, Yulin Tan, Cheng Xi, Nianyuan Ye, Dapeng Wu and Xuezhong Xu

    Citation: World Journal of Surgical Oncology 2020 18:214

    Content type: Review

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  29. Lymph node staging of ductal adenocarcinoma of the pancreatic head (PDAC) by cross-sectional imaging is limited. The aim of this study was to determine the diagnostic accuracy of expanded criteria in nodal sta...

    Authors: Florian N. Loch, Patrick Asbach, Matthias Haas, Hendrik Seeliger, Katharina Beyer, Christian Schineis, Claudius E. Degro, Georgios A. Margonis, Martin E. Kreis and Carsten Kamphues

    Citation: World Journal of Surgical Oncology 2020 18:213

    Content type: Research

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  30. Laparoscopic tumor-specific mesorectal excision (TSME) preserving the left colic artery and superior rectal artery is still a technically challenging procedure. We conducted this study to demonstrate the feasi...

    Authors: Chi Zhang, Hao-tang Wei, Wenqing Hu, Yueming Sun, Qinyuan Zhang, Masanobu Abe, Zhuoran Du, Yingying Xu, Liang Zong and Xiang Hu

    Citation: World Journal of Surgical Oncology 2020 18:212

    Content type: Research

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  31. Cowden’s syndrome is an autosomal dominant disease with variable penetrance, involving the tumor suppressor phosphatase and tension homolog gene, located on chromosome 10q22-23, responsible for cell proliferat...

    Authors: Sofia Miguelote, Roberto Silva, J. L. Fougo, L. E. Barbosa and J. P. Araújo Teixeira

    Citation: World Journal of Surgical Oncology 2020 18:211

    Content type: Case report

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  32. Ischemia–reperfusion injury is harmful in partial nephrectomy (PN) in renal cell carcinoma. Choosing an appropriate surgical method is important to reduce ischemia–reperfusion injury. This study aimed to compa...

    Authors: Jinhong Xu, Shuxiong Xu, Biao Yao, Run Xu, Yuangao Xu, Fa Sun, Qian Qiu and Hua Shi

    Citation: World Journal of Surgical Oncology 2020 18:210

    Content type: Research

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  33. Angiopoietin-Tie2 and nitric oxide pathway is crucial in tumor angiogenesis and closely correlates with tumor development, growth, and metastasis. This study aimed to investigate the angiopoietin-Tie2 and nitr...

    Authors: Hsiang-Ling Wu, You-Hsiang Chu, Ying-Hsuan Tai, Mei-Yung Tsou, Cheng-Hsien Wu, Wen-Liang Lo, Shyh-Kuan Tai, Chun-Chang Yeh and Chih-Cherng Lu

    Citation: World Journal of Surgical Oncology 2020 18:209

    Content type: Research

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  34. Pancreatic neuroendocrine tumors (PNET) are rare, with a significant malignant potential. This study aimed to determine outcomes of patients with resected PNETs according to the cystic component and confirm th...

    Authors: Ange Khalil, Jacques Ewald, Ugo Marchese, Aurélie Autret, Jonathan Garnier, Patricia Niccoli, Gilles Piana, Flora Poizat, Marc Giovannini, Jean-Robert Delpero and Olivier Turrini

    Citation: World Journal of Surgical Oncology 2020 18:208

    Content type: Research

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  35. One of the most severe complications of low anterior rectal resection is anastomotic leakage (AL). The creation of a loop ileostomy (LI) reduces the prevalence of AL requiring surgical intervention. However, u...

    Authors: Marcin Zeman, Marek Czarnecki, Andrzej Chmielarz, Adam Idasiak, Maciej Grajek and Agnieszka Czarniecka

    Citation: World Journal of Surgical Oncology 2020 18:207

    Content type: Research

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  36. The role of renal artery embolization (RAE) in the therapeutic armamentarium is always controversial. The present study aimed to assess the safety and the surgical outcomes of the instant renal artery emboliza...

    Authors: Guangxin Tang, Xiaoxu Chen, Jianwei Wang, Wei He and Zhihong Niu

    Citation: World Journal of Surgical Oncology 2020 18:206

    Content type: Research

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  37. Anastomotic leakage (AL) significantly impairs short-term outcomes. The impact on the long-term outcomes remains unclear. This study aimed to identify the risk factors for AL and the impact on long-term surviv...

    Authors: Marius Kryzauskas, Augustinas Bausys, Austeja Elzbieta Degutyte, Vilius Abeciunas, Eligijus Poskus, Rimantas Bausys, Audrius Dulskas, Kestutis Strupas and Tomas Poskus

    Citation: World Journal of Surgical Oncology 2020 18:205

    Content type: Research

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  38. Due to the controversy over the prognostic significance of Borrmann type in patients with gastric cancer (GC), the present study was to investigate the clinical value of Borrmann type in advanced GC.

    Authors: Xiao-Hai Song, Wei-Han Zhang, Kai-Liu, Xiao-Long Chen, Lin-Yong Zhao, Xin-Zu Chen, Kun-Yang, Zong-Guang Zhou and Jian-Kun Hu

    Citation: World Journal of Surgical Oncology 2020 18:204

    Content type: Research

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  39. Morphologically, osteofibrous dysplasia-like adamantinoma is thought to be intermediate between osteofibrous dysplasia and adamantinoma. Its treatment is not well established owing to its rarity.

    Authors: Yuji Yamamura, Makoto Emori, Nobuyuki Takahashi, Mitsumasa Chiba, Junya Shimizu, Yasutaka Murahashi, Shintaro Sugita, Kousuke Iba, Tadashi Hasegawa and Toshihiko Yamashita

    Citation: World Journal of Surgical Oncology 2020 18:203

    Content type: Case report

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  40. Thymic epithelial tumors are rare neoplasias. There are no internationally accepted standards to treat this complex oncological disease. The studies on which our knowledge is based frequently have methodologic...

    Authors: Marius Kemper, Mona Moradzadeh, Eugen Bellon, Ahmad S. Bahar, Rainer Grotelüschen, Matthias Reeh, Jakob R. Izbicki and Kai Bachmann

    Citation: World Journal of Surgical Oncology 2020 18:202

    Content type: Research

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  41. To estimate the prognostic value of positive surgical margins (PSM) location and perineural invasion (PNI) for biochemical recurrence (BCR) in patients undergoing radical prostatectomy (RP).

    Authors: Zhenpeng Lian, Hongtuan Zhang, Zhaowei He, Shenfei Ma, Xiaoming Wang and Ranlu Liu

    Citation: World Journal of Surgical Oncology 2020 18:201

    Content type: Research

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  42. Recent phase III randomized trials have suggested that neoadjuvant chemotherapy followed by interval debulking surgery (NACT-IDS) is a treatment option for patients with advanced epithelial ovarian cancer. Thi...

    Authors: Kazuto Nakamura, Yoshikazu Kitahara, Toshio Nishimura, Soichi Yamashita, Keiko Kigure, Ikuro Ito and Tatsuya Kanuma

    Citation: World Journal of Surgical Oncology 2020 18:200

    Content type: Research

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  43. Several randomized controlled trials (RCTs) compared the effects of laparoscopic hepatectomy (LH) and radiofrequency ablation (RFA) for the treatment of hepatocellular carcinoma (HCC), but the results have rem...

    Authors: Shan Jin, Shisheng Tan, Wen Peng, Ying Jiang and Chunshan Luo

    Citation: World Journal of Surgical Oncology 2020 18:199

    Content type: Review

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  44. To assess the feasibility and short-term outcomes of neoadjuvant chemoradiotherapy (CCRT) followed by transanal total mesorectal excision assisted by single-port laparoscopic surgery (TaTME-SPLS) for low-lying...

    Authors: Yen-Jung Lu, Chien-Hsin Chen, En-Kwang Lin and Szu-Yuan Wu

    Citation: World Journal of Surgical Oncology 2020 18:198

    Content type: Research

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  45. Systemic immune-inflammation index (SII) has been suggested to be effective to reflect the inflammatory status and thus may be an underlying biomarker for prognosis prediction. This hypothesis has been demonst...

    Authors: Yongfang Ji and Haiyan Wang

    Citation: World Journal of Surgical Oncology 2020 18:197

    Content type: Review

    Published on:

  46. Patients with stage II deficient mismatch repair (dMMR) show a better prognosis than patients with colorectal cancer (CRC) with proficient mismatch repair (pMMR). However, this beneficial effect is decreased i...

    Authors: Bingyan Wang, Fei Li, Limei Guo, Siyi Lu, Junren Ma, Yanpeng Ma, Yan Meng, Junwei Wang, Xin Zhou and Wei Fu

    Citation: World Journal of Surgical Oncology 2020 18:196

    Content type: Research

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  47. Although hereditary non-polyposis colorectal cancer (HNPCC) could be subtyped into proficient or deficient mismatch repair gene expression (pMMR or dMMR), distinct clinical features between these two subgroups...

    Authors: Ci-Yuan Sun, Jy-Ming Chiang, Tse-Ching Chen, Hsin-Yun Hung and Jeng-Fu You

    Citation: World Journal of Surgical Oncology 2020 18:195

    Content type: Research

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  48. Frailty results in a high risk for disability, hospitalization, and mortality. This study aimed to investigate perioperative details of frail patients who underwent pancreatectomy and whether frailty can be a ...

    Authors: Yutaka Nakano, Yuki Hirata, Tatsuya Shimogawara, Toru Yamada, Koki Mihara, Ryo Nishiyama, Shin Nishiya, Hideki Taniguchi and Tomohisa Egawa

    Citation: World Journal of Surgical Oncology 2020 18:194

    Content type: Research

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  49. The impact of primary tumor resection (PTR) on the prognosis of unresectable metastatic colorectal cancer (mCRC) patients remains debatable. We aimed to develop several prognostic nomograms which could be usef...

    Authors: Yi Yang, Yujie Lu, Wen Jiang, Jinzhou Zhu and Su Yan

    Citation: World Journal of Surgical Oncology 2020 18:193

    Content type: Research

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  50. Several studies have reported the Cyclooxygenase 2 (COX-2) rs689466 polymorphism as a susceptibility locus of colorectal cancer (CRC), but their findings are inconsistent. Thus, this meta-analysis was performe...

    Authors: Yong-Chen Zhang, Hui Zhao, Chen Chen and Mohammad Amzad Ali

    Citation: World Journal of Surgical Oncology 2020 18:192

    Content type: Research

    Published on:

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