Table 1 Comparison of patient clinical characteristics
Primary angiosarcoma, n (%) | Secondary angiosarcoma, n (%) | p value | |
|---|---|---|---|
Total | 100 | 147 | |
Median age | 50–54 | 70–74 | |
< 65 | 64 (64.0) | 38 (25.9) | |
≥ 65 | 36 (36.0) | 109 (74.1) | p < 0.001 |
Race | |||
White | 79 (79.0) | 133 (90.5) | |
Non-whitea | 21 (21.0) | 14 (9.5) | p = 0.011 |
Site | |||
Centralb | 4 (4.0) | 13 (8.9) | |
Inner quandrant | 13 (13.0) | 14 (9.5) | |
Outer quandrant | 16 (16.0) | 24 (16.3) | |
Overlap | 31 (31.0) | 26 (17.7) | |
NOSc | 36 (36.0) | 70 (47.6) | p = 0.058 |
Grade | |||
G1 | 21 (21.0) | 10 (6.8) | |
G2 | 28 (28.0) | 19 (12.9) | |
G3 | 27 (27.0) | 47 (32.0) | |
Gxd | 24 (24.0) | 71 (48.3) | p < 0.001 |
Tumour size | |||
< 5 cm | 49 (49.0) | 79 (53.8) | |
5-10 cm | 33 (33.0) | 54 (36.7) | |
> 10 cm | 18 (18.0) | 14 (9.5) | p = 0.15 |
Tumour spread | |||
Local | 74 (74.0) | 67 (45.6) | |
Regional | 18 (18.0) | 74 (50.3) | |
Distant | 8 (8.0) | 6 (4.1) | p < 0.001 |
Tumour extension | |||
Confined | 79 (79.0) | 68 (46.3) | |
Local infiltration | 10 (10.0) | 41 (27.9) | |
Deep | 11 (11.0) | 38 (25.8) | p < 0.001 |
Total number | |||
1 | 75 (75.0) | 0 (0) | |
2 | 21 (21.0) | 96 (65.3) | |
≥ 3 | 4 (4.0) | 51 (34.7) | p < 0.001 |
Chemotherapy | |||
Yes | 37 (37.0) | 32 (21.8) | |
No | 63 (63.0) | 115 (78.2) | p = 0.09 |
Radiation | |||
Yes | 31 (31.0) | 25 (17.0) | |
No | 69 (69.0) | 122 (83.0) | p = 0.01 |
Surgery | |||
Yes | 96 (96.0) | 146 (99.3) | |
No | 4 (4.0) | 1 (0.7) | p < 0.001 |