Table 2 Univariate and multifactorial analysis in 256 cases of esophageal cancer
From: A possible combined appraisal pattern: predicting the prognosis of patients after esophagectomy
Variable | Overall survival | Recurrence-free survival | ||||||
|---|---|---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | |||||
HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
Age (years) | 1.03 (0.99–1.07) | 0.10 | 1.04 (0.99–1.09) | 0.10 | 0.99 (0.95–1.05) | 0.95 | ||
Sex (female vs male) | 1.69 (0.99–2.89) | 0.06 | 1.38 (0.74–2.58) | 0.31 | 2.66 (1.05–6.77) | 0.04 | 1.56 (0.59–4.11) | 0.37 |
ACCI | 0.16 | 0.72 | ||||||
3–4 vs 1–2 | 0.98 (0.62–1.54) | 0.92 | 1.02 (0.61–1.72) | 0.93 | 0.82 (0.43–1.57) | 0.55 | ||
5–7 vs 1–2 | 1.67 (0.91–3.06) | 0.10 | 1.58 (0.75–3.32) | 0.23 | 1.13 (0.44–2.90) | 0.80 | ||
Size (cm) | 1.18 (1.04–1.32) | 0.01 | 1.07 (0.93–1.24) | 0.35 | 1.20 (1.01–1.43) | 0.04 | 0.84 (0.67–1.06) | 0.14 |
TNM | 0.00 | 0.00 | 0.01 | |||||
II vs I | 1.14 (0.67–1.92) | 0.64 | 1.03 (0.58–1.86) | 0.91 | 1.06 (0.43–2.62) | 0.90 | 0.34 (0.12–0.99) | 0.04 |
III vs I | 2.24 (1.36–3.66) | 0.00 | 1.56 (0.82–2.95) | 0.17 | 4.24 (1.98–9.10) | 0.00 | 1.22 (0.47–3.19) | 0.69 |
Bleeding (< 140 vs ≥ 140) | 1.41 (0.94–2.12) | 0.10 | 1.07 (0.67–1.69) | 0.79 | 1.54 (0.85–2.80) | 0.16 | 1.45 (0.78–2.71) | 0.24 |
Vascular invasion (no vs yes) | 2.14 (1.19–3.84) | 0.01 | 1.45 (0.75–2.80) | 0.27 | 2.43 (1.08–5.47) | 0.03 | 0.85 (0.33–2.23) | 0.75 |
Complications | 0.08 | 0.04 | 0.36 | |||||
Mild vs no | 0.73 (0.44–1.19) | 0.20 | 1.04 (0.60–1.81) | 0.88 | 1.24 (0.62–2.46) | 0.54 | 1.12 (0.53–2.35) | 0.78 |
Severe vs no | 1.56 (0.88–2.75) | 0.13 | 1.40 (0.75–2.64) | 0.29 | 2.76 (1.26–6.02) | 0.11 | 2.91 (1.28–6.62) | 0.01 |
Chemoradiotherapy (no vs yes) | 1.60 (1.07–2.40) | 0.02 | 0.86 (0.48–1.55) | 0.62 | 8.36 (4.01–17.42) | 0.00 | 12.69 (4.75–33.90) | 0.00 |
Metastasis (no vs yes) | 2.34 (1.50–3.66) | 0.00 | 2.15 (1.16–4.00) | 0.02 | ||||
NC (109/L) | 1.17 (1.04–1.31) | 0.01 | 1.02 (0.86–1.20) | 0.86 | 1.12 (0.94–1.34) | 0.22 | ||
Hospital stay (D) | 1.03 (0.99–1.07) | 0.16 | 1.02 (0.99–1.06) | 0.25 | 1.03 (0.97–1.10) | 0.34 | ||
PLR (< 154.9 vs ≥ 154.9) | 1.55 (0.99–2.43) | 0.06 | 1.42 (0.80–2.51) | 0.23 | 1.45 (0.74–2.83) | 0.27 | ||
SMI (height vs low) | 0.09 (0.06–0.14) | 0.00 | 0.62 (0.32–1.21) | 0.16 | ||||
CIN (< 51.6 vs ≥ 51.6) | 0.43 (0.27–0.69) | 0.00 | 0.90 (0.43–1.89) | 0.77 | 0.83 (0.35–1.98) | 0.69 | ||
CAS | 0.00 | 0.00 | 0.02 | 0.00 | ||||
G2 vs G1 | 4.96 (2.84–8.86) | 0.00 | 4.77 (2.59–8.80) | 0.00 | 1.97 (1.50–1.86) | 0.02 | 1.75 (1.38–1.48) | 0.01 |
G3 vs G1 | 8.60 (4.57–16.21) | 0.00 | 8.36 (4.19–16.67) | 0.00 | 3.31 (1.83–7.92) | 0.01 | 4.75 (1.78–12.69) | 0.00 |