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Table 3 Comparison of malignancy-differentiating ability between FNAB and FNAB & BRAF among nodules with macrocalcification

From: Association between macrocalcification and papillary thyroid carcinoma and corresponding valuable diagnostic tool: retrospective study

 

FNAB

FNAB and BRAF V600E

P value

Area under the curve

0.84

0.94

0.03

Sensitivity (%)

67.2%

100.0%

<0.01

Specificity (%)

100.0%

88.9%

0.125

Diagnostic accuracy

80.0%

96.0%

<0.01

  1. Corresponding fourfold table and calculation formula can be found in Supplementary Tables 1 and 2
  2. Abbreviations: FNAB Fine needle aspiration biopsy, BRAF V600E Proto-Oncogene Proteins B-raf V600E
  3. †Chi-square test, ‡Z test, otherwise McNemar’s test with exact significance was used