Table 1 Characteristics between women with ovarian preservation and bilateral salpingo-oophorectomy
Variable | n = 116 | Ovary saved | ||
|---|---|---|---|---|
BSO | OP | P | ||
86 | 30 | |||
Age (%) | < 0.001 | |||
≤ 46 | 64 (55.2) | 34 (39.5) | 30 (100.0) | |
> 46 | 52 (44.8) | 52 (60.5) | 0 (0.0) | |
FIGO stage (%) | 0.227 | |||
I | 71 (61.2) | 48 (55.8) | 23 (76.7) | |
II | 13 (11.2) | 11 (12.8) | 2 (6.7) | |
III | 30 (25.9) | 25 (29.1) | 5 (16.7) | |
IV | 2 (1.7) | 2 (2.3) | 0 (0.0) | |
Tumor size (%) | 0.012 | |||
≤ 2.4 cm | 34 (32.7) | 19 (25.0) | 15 (53.6) | |
> 2.4 cm | 70 (67.3) | 57 (75.0) | 13 (46.4) | |
Preoperative HPV (%) | 1 | |||
Negative | 7 (8.9) | 5 (8.1) | 2 (11.8) | |
Positive | 72 (91.1) | 57 (91.9) | 15 (88.2) | |
Positive | ||||
Unknown specific type | 13 (18.1) | 10 (17.5) | 3 (20.0) | |
Known | ||||
With HPV16 | 14 (23.7) | 11 (23.4) | 3 (25.0) | |
With HPV18 | 46 (78.0) | 37 (78.7) | 9 (75.0) | |
Other 12 high-risk HPVs | 10 (16.9) | 8 (17.0) | 2 (16.7) | |
Histological heterogeneity (%) | 0.777 | |||
Pure | 47 (40.5) | 36 (41.9) | 11 (36.7) | |
Mix | 69 (59.5) | 50 (58.1) | 19 (63.3) | |
Mix | 69 | 0.395 | ||
NEC differentiation | 12 (17.4) | 7 (14.0) | 5 (26.3) | |
NECC dominant | 57 (82.6) | 43 (86.0) | 14 (73.7) | |
Mix | 69 | 0.3 | ||
Squamous | 12 (17.4) | 9 (18.0) | 3 (15.8) | |
Adenocarcinoma | 54 (78.3) | 40 (80.0) | 14 (73.7) | |
Both | 3 (4.3) | 1 (2.0) | 2 (10.5) | |
LNM (%) | 0.4 | |||
Negative | 84 (72.4) | 60 (69.8) | 24 (80.0) | |
Positive | 32 (27.6) | 26 (30.2) | 6 (20.0) | |
Positive | 32 | 0.732 | ||
Pelvic | 28 (87.5) | 22 (84.6) | 6 (100.0) | |
Pelvic & para-aortic | 4 (12.5) | 4 (15.4) | 0 (0.0) | |
Positive | 32 | 0.136 | ||
LNM ratio low | 21 (65.6) | 15 (57.7) | 6 (100.0) | |
LNM ratio high | 11 (34.4) | 11 (42.3) | 0 (0.0) | |
Parametrial involvement (%) | 0.09 | |||
Negative | 105 (90.5) | 75 (87.2) | 30 (100.0) | |
Positive | 11 (9.5) | 11 (12.8) | 0 (0.0) | |
Vaginal invasion (%) | 0.02 | |||
Negative | 91 (79.8) | 63 (74.1) | 28 (96.6) | |
Positive | 23 (20.2) | 22 (25.9) | 1 (3.4) | |
Incisal margin (%) | 0.251 | |||
Negative | 107 (93.9) | 78 (91.8) | 29 (100.0) | |
Positive | 7 (6.1) | 7 (8.2) | 0 (0.0) | |
LUSI (%) | 0.084 | |||
Negative | 94 (81.0) | 66 (76.7) | 28 (93.3) | |
Positive | 22 (19.0) | 20 (23.3) | 2 (6.7) | |
DIM (%) | 0.044 | |||
Superficial 1/3 | 32 (28.1) | 20 (23.8) | 12 (40.0) | |
Middle 1/3 | 38 (33.3) | 26 (31.0) | 12 (40.0) | |
Deep 1/3 | 44 (38.6) | 38 (45.2) | 6 (20.0) | |
LVSI (%) | 1 | |||
Negative | 17 (15.6) | 13 (15.9) | 4 (14.8) | |
Positive | 92 (84.4) | 69 (84.1) | 23 (85.2) | |
Radiotherapy (%) | 0.229 | |||
Unaccepted | 18 (18.0) | 11 (14.7) | 7 (28.0) | |
Accepted | 82 (82.0) | 64 (85.3) | 18 (72.0) | |