From: Prognostic analysis of 2–5 cm diameter gastric stromal tumors with exogenous or endogenous growth
Factors | Univariate analysis RFS | Multivariate analysis RFS | ||
---|---|---|---|---|
HR (95% CI) | p-value | HR (95% CI) | p-value | |
Age | 0.162 | |||
≤ 65 | Reference | |||
> 65 | 0.951 (0.886 ~ 1.020) | |||
Gender | 0.614 | |||
Male | Reference | |||
Female | 0.672 (0.144 ~ 3.144) | |||
GI bleeding | ||||
No | Reference | 0.044 | Reference | 0.179 |
Yes | 0.293 (0.088 ~ 0.968) | − 1.348 (− 14.456 ~ 2.707) | ||
Growth pattern | 0.938 | |||
Exogenous | Reference | |||
Endogenous | 0.000 (0.000 ~ 7.291E) | |||
Tumor site | 0.839 | |||
Small bend | ||||
Large bend | Reference | |||
Fundus | 1.099 (0.442 ~ 2.734) | |||
Resection style | 0.695 | |||
Mesenchymal resection | Reference | |||
Distal gastrectomy | 0.728 (0.149 ~ 3.757) | |||
Proximal gastrectomy | ||||
Total gastrectomy | ||||
Mitotic index | 0.128 | |||
≤ 5/HPF | Reference | |||
> 5/HPF | 0.001 (0.000 ~ 8.248) | |||
NIH risk grade | 0.117 | |||
Extremely low or low | Reference | |||
Moderate or high | 50.034 (0.224 ~ 3.162) | |||
CD117 | 0.925 | |||
( −) or ( +) | Reference | |||
(+ +) or (+ + +) | 0.849 (0.027 ~ 26.498) | |||
CD34 | 0.249 | |||
( −) or ( +) | Reference | |||
(+ +) or (+ + +) | 7.801 (0.237 ~ 257.082) | |||
Ki-67 index | 0.806 | |||
≤ 5% | Reference | |||
> 5% | 0.970 (0.760 ~ 1.237) | |||
Basic disease | Reference | 0.036 | Reference | 0.588 |
0.276 (0.083 ~ 0.921) | 0.558 (− 7.005 ~ 12.538) | |||
Surgical history | Reference | 0.693 | ||
1.363 (0.293 ~ 6.348) | ||||
Adjuvant imatinib | Reference | 0.686 | ||
1.289 (0.378 ~ 4.397) |