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Table 4 Cox proportional-hazard regression model analysis for OS

From: Prognostic analysis of 2–5 cm diameter gastric stromal tumors with exogenous or endogenous growth

Factors

Univariate analysis

RFS

Multivariate analysis

RFS

HR (95% CI)

p-value

HR (95% CI)

p-value

Age

 

0.162

  

  ≤ 65

Reference

   

  > 65

0.951 (0.886 ~ 1.020)

   

Gender

 

0.614

  

 Male

Reference

   

 Female

0.672 (0.144 ~ 3.144)

   

GI bleeding

 No

Reference

0.044

Reference

0.179

 Yes

0.293 (0.088 ~ 0.968)

 

 − 1.348 (− 14.456 ~ 2.707)

 

Growth pattern

 

0.938

  

 Exogenous

Reference

   

 Endogenous

0.000 (0.000 ~ 7.291E)

   

Tumor site

 

0.839

  

 Small bend

    

 Large bend

Reference

   

 Fundus

1.099 (0.442 ~ 2.734)

   

Resection style

 

0.695

  

 Mesenchymal resection

Reference

   

 Distal gastrectomy

0.728 (0.149 ~ 3.757)

   

 Proximal gastrectomy

    

 Total gastrectomy

    

Mitotic index

 

0.128

  

  ≤ 5/HPF

Reference

   

  > 5/HPF

0.001 (0.000 ~ 8.248)

   

NIH risk grade

 

0.117

  

 Extremely low or low

Reference

   

 Moderate or high

50.034 (0.224 ~ 3.162)

   

CD117

 

0.925

  

 ( −) or ( +)

Reference

   

 (+ +) or (+ + +)

0.849 (0.027 ~ 26.498)

   

CD34

 

0.249

  

 ( −) or ( +)

Reference

   

 (+ +) or (+ + +)

7.801 (0.237 ~ 257.082)

   

Ki-67 index

 

0.806

  

  ≤ 5%

Reference

   

  > 5%

0.970 (0.760 ~ 1.237)

   

Basic disease

Reference

0.036

Reference

0.588

0.276 (0.083 ~ 0.921)

 

0.558 (− 7.005 ~ 12.538)

 

Surgical history

Reference

0.693

  

1.363 (0.293 ~ 6.348)

   

Adjuvant imatinib

Reference

0.686

  

1.289 (0.378 ~ 4.397)