From: Prognostic analysis of 2–5 cm diameter gastric stromal tumors with exogenous or endogenous growth
Factors | Univariate analysis PFS | Multivariate analysis PFS | ||
---|---|---|---|---|
HR (95% CI) | p-value | HR (95% CI) | p-value | |
Age | 0.070 | |||
≤ 65 | Reference | |||
> 65 | 1.041 (0.997 ~ 1.086) | |||
Gender | 0.659 | |||
Male | Reference | |||
Female | 1.234 (0.385 ~ 4.412) | |||
GI bleeding | ||||
No | Reference | 0.520 | ||
Yes | 1.374 (0.521 ~ 3.625) | |||
Growth pattern | 0.048 | 0.058 | ||
Exogenous | Reference | Reference | ||
Endogenous | 0.130 (0.017 ~ 0.986) | 7.070 (0.933 ~ 53.595) | ||
Tumor site | 0.887 | |||
Small bend | ||||
Large bend | Reference | |||
Fundus | 1.046 (0.562 ~ 1.945) | |||
Resection style | 0.041 | 0.045 | ||
Mesenchymal resection | Reference | Reference | ||
Distal gastrectomy | 0.121 (0.016 ~ 0.914) | 2.015 (0.190 ~ 14.438) | ||
Proximal gastrectomy | ||||
Total gastrectomy | ||||
Mitotic index | 0.802 | |||
≤ 5/HPF | Reference | |||
> 5/HPF | 1.261 (0.206 ~ 7.699) | |||
NIH risk grade | 0.798 | |||
Extremely low or low | Reference | |||
Moderate or high | 0.841 (0.224 ~ 3.162) | |||
CD117 | 0.747 | |||
( −) or ( +) | Reference | |||
(+ +) or (+ + +) | 0.590 (0.024 ~ 14.513) | |||
CD34 | 0.813 | |||
( −) or ( +) | Reference | |||
(+ +) or (+ + +) | 1.471 (0.060 ~ 36.235) | |||
Ki-67 index | 0.005 | 0.008 | ||
≤ 5% | Reference | Reference | ||
> 5% | 1.206 (1.057 ~ 1.376) | 1.070 (1.018 ~ 1.125) | ||
Basic disease | Reference | 0.788 | ||
1.144 (0.429 ~ 3.049) | ||||
Surgical history | Reference | 0.049 | Reference | 0.031 |
2.914 (1.004 ~ 8.461) | 3.066 (1.110 ~ 8.474) | |||
Adjuvant imatinib | Reference | 0.278 | ||
2.035 (0.564 ~ 7.342) |