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Table 3 Cox proportional-hazard regression model analysis for PFS

From: Prognostic analysis of 2–5 cm diameter gastric stromal tumors with exogenous or endogenous growth

Factors

Univariate analysis

PFS

Multivariate analysis

PFS

HR (95% CI)

p-value

HR (95% CI)

p-value

Age

 

0.070

  

  ≤ 65

Reference

   

  > 65

1.041 (0.997 ~ 1.086)

   

Gender

 

0.659

  

 Male

Reference

   

 Female

1.234 (0.385 ~ 4.412)

   

GI bleeding

    

 No

Reference

0.520

  

 Yes

1.374 (0.521 ~ 3.625)

   

Growth pattern

 

0.048

 

0.058

 Exogenous

Reference

 

Reference

 

 Endogenous

0.130 (0.017 ~ 0.986)

 

7.070 (0.933 ~ 53.595)

 

Tumor site

 

0.887

  

 Small bend

    

 Large bend

Reference

   

 Fundus

1.046 (0.562 ~ 1.945)

   

Resection style

 

0.041

 

0.045

 Mesenchymal resection

Reference

 

Reference

 

 Distal gastrectomy

0.121 (0.016 ~ 0.914)

 

2.015 (0.190 ~ 14.438)

 

 Proximal gastrectomy

    

 Total gastrectomy

    

Mitotic index

 

0.802

  

  ≤ 5/HPF

Reference

   

  > 5/HPF

1.261 (0.206 ~ 7.699)

   

NIH risk grade

 

0.798

  

 Extremely low or low

Reference

   

 Moderate or high

0.841 (0.224 ~ 3.162)

   

CD117

 

0.747

  

 ( −) or ( +)

Reference

   

 (+ +) or (+ + +)

0.590 (0.024 ~ 14.513)

   

CD34

 

0.813

  

 ( −) or ( +)

Reference

   

 (+ +) or (+ + +)

1.471 (0.060 ~ 36.235)

   

Ki-67 index

 

0.005

 

0.008

  ≤ 5%

Reference

 

Reference

 

  > 5%

1.206 (1.057 ~ 1.376)

 

1.070 (1.018 ~ 1.125)

 

Basic disease

Reference

0.788

  

1.144 (0.429 ~ 3.049)

   

Surgical history

Reference

0.049

Reference

0.031

2.914 (1.004 ~ 8.461)

 

3.066 (1.110 ~ 8.474)

 

Adjuvant imatinib

Reference

0.278

  

2.035 (0.564 ~ 7.342)