Table 4 Univariable and multivariable analyses of RFS before and after PSM

Age

0.994

0.974–1.015

0.577

0.999

0.973–1.026

0.970

Gender, female vs. male

0.680

0.445–1.039

0.075

0.533

0.296–0.958

0.036

0.649

0.386–1.093

0.104

BMI

0.945

0.881–1.014

0.115

0.953

0.875–1.037

0.261

ASA score, high vs low

0.919

0.384–2.195

0.849

0.861

0.293–2.528

0.785

Cirrhosis, yes vs. no

1.057

0.586–1.906

0.854

1.083

0.514–2.286

0.833

Hepatitis B, yes vs. no

1.261

0.764–2.082

0.364

1.261

0.678–2.346

0.463

TBIL, high vs low

1.071

0.592–1.939

0.820

1.285

0.626–2.637

0.494

ALB, low vs high

0.714

0.464–1.098

0.125

0.719

0.427–1.211

0.215

PT, high vs low

1.124

0.595–2.121

0.719

1.023

0.437–2.395

0.958

PLT, low vs high

1.688

1.049–2.718

0.031

2.291

1.259–4.168

0.007

1.453

0.807–2.616

0.213

AFP, high vs low

1.558

0.676–3.590

0.298

1.569

0.620–3.967

0.341

CEA, high vs low

1.114

0.685–1.810

0.664

0.934

0.504–1.730

0.828

CA19-9, high vs low

1.538

0.956–2.475

0.076

1.367

0.731–2.559

0.328

1.715

0.967–3.041

0.065

1.171

0.584–2.346

0.657

CA12-5, high vs low

1.785

1.103–2.887

0.018

1.057

0.565–1.978

0.863

1.766

0.992–3.143

0.053

0.710

0.312–1.615

0.414

Child–Pugh, high vs low

0.753

0.347–1.633

0.473

0.349

0.048–2.542

0.299

Surgical operation, open vs laparoscopic

1.181

0.726–1.919

0.503

1.320

0.761–2.288

0.323

Anatomical liver resection, yes vs. no

0.868

0.545–1.382

0.550

0.942

0.535–1.660

0.837

Extent of resection, major vs minor

1.102

0.938–1.295

0.238

1.147

0.941

1.398

Lymphadenectomy ≥ 6, yes vs. no

1.388

0.907–2.124

0.131

1.396

0.825–2.363

0.214

Operation time

1.002

1.000–1.003

0.069

0.999

0.997–1.002

0.603

1.001

0.999–1.004

0.251

Blood transfusion, yes vs. no

1.518

0.991–2.325

0.055

0.875

0.466–1.641

0.676

1.676

1.003–2.801

0.049

1.244

0.601–2.575

0.556

Blood loss

1.000

1.000–1.000

0.311

1.000

1.000–1.000

0.319

Tumor sizes

1.133

1.052–1.221

0.001

1.139

1.027–1.264

0.014

1.116

1.020–1.220

0.016

1.074

0.933–1.235

0.322

No. of tumors, multiple vs solitary

2.470

1.492–4.090

< 0.001

1.763

0.948–3.279

0.074

3.435

1.687–6.996

0.001

3.501

1.540–7.957

0.003

Clavien-Dindo classification, major vs minor/none

1.039

0.575–1.877

0.900

0.757

0.104–5.509

0.784

Postoperative hospital stay

1.016

1.003–1.030

0.016

1.010

0.992–1.029

0.271

1.019

1.001–1.038

0.036

1.019

0.998–1.040

0.070

Tumor differentiation, low vs. high

1.232

0.905–1.678

0.185

1.151

0.788–1.681

0.467

Lymph node metastasis, yes vs. no

2.573

1.634–4.051

< 0.001

2.140

1.220–3.752

0.008

2.781

1.597–4.846

< 0.001

2.427

1.284–4.589

0.006

Nerve invasion, yes vs. no

2.217

1.371–3.585

0.001

2.451

1.286–4.674

0.006

2.412

1.285–4.525

0.006

2.227

0.891–5.568

0.087

R0 resection, yes vs. no

1.215

0.491–3.006

0.673

0.559

0.219–1.426

0.224