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Table 3 General information of sMPLCs before and after matching

From: Sublobar resection versus lobectomy in the treatment of synchronous multiple primary lung cancer

Factors

Pre-matching

After matching

Lobectomy (n = 65)

Sublobar

(n = 76)

Χ2/t

P

Lobectomy (n = 49)

Sublobar

(n = 49)

Χ2/t

P

Age, years ± SD

62.0 ± 7.4

57.0 ± 10.7

3.25

0.001

61.6 ± 7.6

59.3 ± 10.6

1.18

0.243

Sex, n (%)

  

3.06

0.080

  

0.40

0.527

 Male

28 (43.1%)

22 (28.9%)

  

19 (38.8%)

16 (32.7%)

  

 Female

37 (56.9%)

54 (71.1%)

  

30 (61.2%)

33 (67.3%)

  

Largest tumor size (mm)

22.0 ± 12.5

12.1 ± 7.6

17.7

0.000

17.1 ± 7.4

13.57 ± 8.9

2.14

0.035

 < 20 mm

29 (44.6%)

70 (92.1%)

38.8

0.000

29 (59.2%)

43 (87.8%)

10.26

0.001

 ≥ 20 mm

36 (55.4%)

6 (7.9%)

  

20 (40.8%)

6 (12.2%)

  

Secondary lesion size (mm)

11.7 ± 6.4

7.7 ± 3.3

4.77

0.000

10.0 ± 5.6

8.3 ± 3.5

1.83

0.071

 < 10 mm

26 (40.0%)

54 (71.1%)

15.2

0.000

25 (32.1%)

33 (66.7%)

2.12

0.146

 ≥ 10 mm

39 (60.0%)

22 (28.9%)

  

23 (59.2%)

16 (33.3%)

  

Tumor number

  

0.99

0.608

  

1.26

0.532

 2

54 (83.1%)

64 (84.2%)

  

40 (81.6%)

41 (83.7%)

  

 3

11 (16.9%)

11 (14.5%)

  

9 (18.4%)

7 (14.3%)

  

 ≥ 4

0 (0%)

1 (1.3%)

  

0 (0%)

1 (2.0%)

  

Main lesion staging

  

9.79

0.044

  

1.76

0.622

 IA

51 (78.5%)

72 (94.8%)

  

43 (87.8%)

46 (93.9%)

  

 IB

3 (4.6%)

0 (0%)

  

0 (0%)

0 (0%)

  

 IIA

3 (4.6%)

1 (1.3%)

  

1 (2.0%)

0 (0%)

  

 IIB

2 (3.1%)

0 (0%)

  

1 (2.0%)

1 (2.0%)

  

 IIIA

6 (9.2%)

3 (3.9%)

  

4 (8.2%)

2 (4.1%)

  

Smoking

  

1.2

0.273

  

0.08

0.779

 Yes

13 (20.0%)

10 (13.2%)

  

7 (14.3%)

8 (16.3%)

  

 No

52 (80.0%)

66 (76.8%)

  

42 (87.5%)

41 (84.7%)

  

Family history of lung cancer

  

0.01

0.918

  

0.71

0.399

 Yes

4 (6.1%)

5 (6.6%)

  

2 (4.1%)

4 (8.2%)

  

 No

61 (93.9%)

71 (93.4%)

  

47 (95.9%)

45 (91.8%)

  

Histologic type

  

6.43

0.169

  

7.12

0.870

 Double adenocarcinoma

54 (83.1%)

71 (93.5%)

  

43 (87.8%)

45 (91.9%)

  

 Double squamous

8 (12.3%)

2 (2.6%)

  

4 (8.2%)

2 (4.1%)

  

 Adenocarcinoma-squamous

1 (1.5%)

1 (1.3%)

  

1 (2.0%)

1 (2.0%)

  

 Squamous-adenocarcinoma

1 (1.5%)

0 (0%)

  

0 (0%)

0 (0%)

  

 Other

1 (1.5%)

2 (2.6%)

  

1 (2.0%)

1 (2.0%)

  

Differentiation

  

21.7

0.000

  

4.98

0.083

 High

25 (38.5%)

57 (75.0%)

  

25 (51.0%)

34 (69.4%)

  

 Moderate

18 (27.7%)

13 (17.1%)

  

11 (22.4%)

10 (20.4%)

  

 Poorly

22 (33.8%)

6 (7.9%)

  

13 (26.6%)

5 (10.2%)

  

Complications

  

3.69

0.297

  

7.49

0.112

 0

35 (53.8%)

31 (40.8%)

  

25 (51.0%)

16 (32.7%)

  

 1

17 (26.2%)

31 (40.8%)

  

12 (24.5%)

23 (46.9%)

  

 2

11 (16.9%)

11 (14.5%)

  

9 (18.4%)

8 (16.3%)

  

 ≥ 3

2 (3.1%)

3 (3.9%)

  

3 (6.1%)

2 (4.1%)

  

Simultaneous surgery

  

5.25

0.022

  

7.51

 

 Yes

51 (78.5%)

46 (60.5%)

  

38 (77.6%)

25 (51.0%)

 

0.006

 No

14 (21.5%)

30 (39.5%)

  

11 (22.4%)

24 (49.0%)

  

Second tumor surgery method

  

37.7

0.000

  

15.68

 

 Lobectomy

36 (55.4%)

6 (7.9%)

  

24 (49.0%)

6 (12.2%)

  

 Segmentectomy

7 (10.8%)

17 (22.4%)

  

6 (12.2%)

12 (24.5%)

  

 Wedge

22 (33.8%)

53 (69.7%)

  

19 (38.8%)

31 (63.3%)

  

Chemotherapy

  

5.01

0.025

  

1.10

0.294

 Yes

11 (16.9%)

4 (5.2%)

  

6 (12.2%)

3 (6.1%)

  

 No

54 (83.1%)

72 (94.8%)

  

43 (87.8%)

46 (93.9%)

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