Increased D-dimer level was a poor predictor of neuroblastoma, especially in the high-risk group

Table 1 Baseline clinical characteristics of 365 patients with NB

Variable	N	%	D-dimer median (mg/L)	P
Gender
Male	212	58.08	1.64	0.427
Female	153	41.92	0.89	0.427
Age (months)
≤ 18	118	32.33	0.80	0.002
> 18	247	67.67	2.24	0.002
Tumor site
Mediastinal tumor	69	18.90	0.35	< 0.001
Other position tumor	296	81.10	1.52	< 0.001
Pathology classification
FH	147	44.55	0.47	< 0.001
UFH	183	55.45	2.85
Unknown	35	/
Bone marrow metastasis
Yes	130	35.62	3.83	< 0.001
No	235	64.38	0.56	< 0.001
Bone metastasis
Yes	103	29.60	4.00	< 0.001
No	245	70.40	0.75
Unknown	17	/
NMYC status
Amplified	68	20.80	6.00	< 0.001
Not amplified	259	79.20	0.91
Unknown	38	/
INSS stage
1,2,4s	64	17.53	0.34	< 0.001
3,4	301	82.47	1.64	< 0.001
COG risk classification
Non-high risk	142	38.90	0.42	< 0.001
High risk	223	61.10	2.88	< 0.001

FH favorable histology, UFH unfavorable histology, INSS International Neuroblastoma Staging System

ISSN: 1477-7819