Fig. 1

Mammogram and magnetic resonance imaging (MRI) showing ipsilateral breast cancer relapse before neoadjuvant antihormone therapy. a Mammogram of the right breast in a mediolateral oblique view with suspicion of a relapse BIRADS 4, ACRb. It shows increased parenchymal density of the upper right quadrant compared to the previous follow-ups, progressive microcalcifications medial to the clips (arrow), and progressive mamilla retraction. b T1-weighted transverse axial dynamic contrast-enhanced MRI with fat suppression showing asymmetric accumulation of contrast and restricted diffusion of the whole right breast including the mammilla. There is subcutaneous edema of the right breast, but no sign of lymph node metastases or distant metastases