Clinical characteristics and outcomes of gastrointestinal stromal tumor patients receiving surgery with or without TKI therapy: a retrospective real-world study

Table 1 Clinical characteristics of 204 intermediate- and 331 high-risk GIST patients

Characteristic		Middle (n = 204)	High(n = 331)	P value
Age	≤ 60	102	174	0.565
	> 60	102	157
Sex	Male	90	196	0.001
	Female	114	135
BMI (kg/m²)	≤ 22.78	101	139	0.908
	> 22.78	103	19
Anemia	Yes	22	34	0.401
	No	182	277
Primary tumor site	Stomach	140	141	< 0.001
	DU + SM	51	154
	Others	13	36
Tumor size(cm)	< 5	70	47	< 0.001
	5–10	133	176
	> 10	1	108
Histological variant	Spindle	162	207	0.032
	Epithelioid	25	71
	Mixed	17	53
Mitotic rate	< 5	134	94	< 0.001
	5–10	68	152
	> 10	2	85
Ki-67 index(%)	< 5	104	80	< 0.001
	5–10	77	89
	> 10	23	152
TKI therapy	Regular	133	281	< 0.001
	Irregular	30	41
	No drug	41	9

ISSN: 1477-7819