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Table 4 Univariable and multivariable analysis for overall survival (OS)

From: The efficacy and safety of Nab-paclitaxel plus gemcitabine versus mFOLFIRINOX in the first-line treatment of metastatic pancreatic cancer: a retrospective study

Variables

Univariable analysis

Multivariable analysis

HR (95% CI)

P value

HR (95% CI)

P value

Treatment regimen

 FFX vs AG

1.193 (0.589–2.523)

0.621

  

Age (years)

  ≥ 60 vs < 60

0.742 (0.365–1.511)

0.411

  

Gender

 Male vs female

0.999 (0.465–2.146)

0.997

  

Baseline CA19-9, U/mL

 Elevated (> 37) vs normal

0.976 (0.449–2.121)

0.951

  

Baseline CEA, ng/mL

 Elevated (> 7.2) vs normal

0.731 (0.363–1.473)

0.381

  

Tumor site of pancreas

 Head/neck vs body/tail

0.724 (0.354–1.479)

0.375

  

Number of metastasis

  ≥ 2 vs 1

1.672 (0.818–3.416)

0.158

  

Liver metastasis

 Yes vs no

1.857 (0.844–4.085)

0.124

  

Combined with radiotherapy

 Yes vs no

0.697 (0.347–1.401)

0.311

  

PNI (prognostic nutrition index)

  < 43.7 vs ≥ 43.7

2.310 (1.098–4.858)

0.027*

2.252 (1.021–4.959)

0.044*