Fig. 1

HIPEC treatment influences postoperative CRP levels. CRP levels after CRS/HIPEC do not return to normal, even without any infectious complication (A). With any infectious complication, CRP increases after HIPEC performed with any of the three protocols (B). In absence of infectious complications, CRP increases after mitomycinC and cisplatin based HIPEC (C), while returning to normal values after HIPEC performed with oxaliplatin (C). The graphs illustrates the postoperative CRP values, plotted as median and IQR