Author | Year | Country | Sample size | Age (years) Median (range) | Study design | Study duration | Metastatic status | Treatment | Follow-up (months) | Cut-off value | Cut-off selection | Patients of low/high SII | Survival endpoints | Survival analysis type | Study center | NOS score |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bauckneht, M. | 2021 | Italy | 519 | 74 (50–90) | Retrospective | 2013–2020 | mCRPC | Radium-223 | 10.7 | 768.8 | ROC curve | 260/132 | OS | Multivariate | Multicenter | 7 |
Donate-Moreno, M. J. | 2020 | Spain | 80 | 72.7 | Prospective | 2014–2018 | mCRPC | Hormone therapy + chemotherapy | 19 | 535 | Literature | 47/33 | OS | Univariate | Single center | 9 |
Fan, L. | 2018 | China | 104 | 72 | Retrospective | 2013–2017 | mCRPC | Hormone therapy + chemotherapy | 19.2 | 200 | ROC curve | NR | OS, PFS | Multivariate | Single center | 6 |
Kobayashi, H. | 2022 | Japan | 144 | 71 | Retrospective | 2008–2018 | mCRPC | Chemotherapy | 3–36 | 636 | Median value | 72/72 | OS, PFS | Multivariate | Single center | 7 |
Lolli, C. | 2016 | Italy | 230 | 74 (45–90) | Retrospective | 2011–2015 | mCRPC | Hormone therapy + chemotherapy | 18 | 535 | X-tile software | 98/132 | OS | Univariate | Single center | 8 |
Man, Y. N. | 2019 | China | 179 | 70 (51–88) | Retrospective | 2010–2018 | mCRPC | Hormone therapy + chemotherapy | 24 (2–118) | 535 | Literature | 85/94 | OS | Multivariate | Single center | 8 |
Pan, Z. | 2020 | China | 126 | 64 (43–76) | Retrospective | 2013–2015 | Nonmetastatic PCa | Radical prostatectomy | To June 2019 | 617 | Mean value | 72/54 | OS | Multivariate | Single center | 7 |
Rajwa, P. | 2021 | Austria | 6,039 | 61 | Retrospective | 2000–2011 | Nonmetastatic PCa | Radical prostatectomy | 44 | 620 | ROC curve | 4,341/1698 | bRFS | Multivariate | Multicenter | 8 |
Wang, S. | 2022 | China | 291 | 66.13 | Retrospective | 2014–2019 | Nonmetastatic PCa | Radical prostatectomy | 48 | 528.54 | ROC curve | 129/162 | bRFS | Multivariate | Single center | 8 |
Zapala, P. | 2022 | Poland | 421 | 65 | Retrospective | 2012–2018 | Nonmetastatic PCa | Radical prostatectomy | 69 | 900 | ROC curve | 203/218 | OS | Multivariate | Single center | 8 |